MUÑOZ VENTURELLI, PAULA ANDREA
Preferred name
MUÑOZ VENTURELLI, PAULA ANDREA
Main Affiliation
Email
paumunoz@udd.cl
ORCID
0000-0003-1869-2255
Scopus Author ID
56071369200
118 results
Now showing 1 - 10 of 118
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Item type:Product, Dataset - Post-COVID-19 condition: a sex-based analysis of clinical and laboratory trends(2024) ;DELFINO, CARLOS; ; ; RIVIOTTA, AMY LISA3 - Some of the metrics are blocked by yourconsent settings
Item type:Publication, STatin TReatment for COVID-19 to Optimise NeuroloGical recovERy (STRONGER): study protocol for a randomised, open label clinical trial in patients with persistent neurological symptoms after COVID-19 infection(BMJ, 2025-04) ;Carlos Delfino ;Cheryl Carcel ;Xiaolei Lin; Sharon L Naismith<jats:sec> <jats:title>Introduction</jats:title> <jats:p>Increasing awareness of the high frequency, wide spectrum and disabling nature of symptoms that can persist following COVID-19 infection has prompted the investigation of management strategies. Our study aims to determine the effectiveness of atorvastatin on cognitive function, physical activity, mood, health-related quality of life and features of neurovascular impairment and neuroinflammation in adults with ongoing neurological symptoms after COVID-19 infection.</jats:p> </jats:sec> <jats:sec> <jats:title>Methods and analysis</jats:title> <jats:p>The STatin TReatment for COVID-19 to Optimise NeuroloGical recovERy study is an ongoing international, investigator-initiated and conducted, multicentre, prospective, randomised, open label, blinded endpoint trial with fixed time points for outcome assessments. A total of 410 participants with long covid neurological symptoms were planned to be randomly assigned to either the intervention group to receive 40 mg atorvastatin for 12 months or to a control group of no treatment, on top of usual care.</jats:p> </jats:sec> <jats:sec> <jats:title>Ethics and dissemination</jats:title> <jats:p>This study protocol was designed, implemented and reported, in accordance with the International Conference on Harmonisation guidelines for Good Clinical Practice, the National Health and Medical Research Council of Australia, the National Statement on Ethical Conduct in Human Research and with the ethical principles laid down in the World Medical Association Declaration of Helsinki. Central ethics committee approval was obtained from Sydney Local Health District Royal Prince Alfred Hospital Ethics (No: X21-0113 and 2021/ETH00777 10) in Australia. Site-specific ethics committee approvals were obtained elsewhere before any local study activities. All participants provided written informed consent.</jats:p> </jats:sec> <jats:sec> <jats:title>Trial registration number</jats:title> <jats:p>The study protocol is registered at Clinicaltrials.gov (<jats:ext-link xmlns:xlink="http://www.w3.org/1999/xlink" ext-link-type="clintrialgov" xlink:href="NCT04904536">NCT04904536</jats:ext-link>).</jats:p> </jats:sec>3 - Some of the metrics are blocked by yourconsent settings
Item type:Publication, Search Results for WOS:001330264900057 (Accession Number) Recommendations for Implementing the INTERACT3 Care Bundle for Intracerebral Haemorrhage in Latin America: A delphi Study 1 of 1 Recommendations for Implementing the INTERACT3 Care Bundle for Intracerebral Haemorrhage in Latin America: A delphi Study(2024) ;ALLENDE, MARÍA IGNACIA; ;GONZALEZ MC CAWLEY, FRANCISCA ;Francisca Bascur GutierrezStuart Craig4 - Some of the metrics are blocked by yourconsent settings
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Item type:Product, Dataset - Coupling between neural oscillations and white matter integrity reveals cognitive computational profiles following COVID-19(OpenEuro, 2026); ; ;MATÍAS IRIARTE CARTER ;VÍCTOR MÁRQUEZMARIA PAZ DE LOS ANGELES MARTINEZ MOLINA - Some of the metrics are blocked by yourconsent settings
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Item type:Publication, Quality of Functional Outcome and its determinants in ICH. Insights from the INTERACT3 trial(2025) ;CARLOS DELFINO; Anderson, Craig2 - Some of the metrics are blocked by yourconsent settings
Item type:Publication, Scopus© Citations 8 1 - Some of the metrics are blocked by yourconsent settings
Item type:Publication, Addressing sex and gender differences in stroke risk and management: A scientific statement from the World Stroke Organization(SAGE Publications, 2025-10-23) ;Cheryl Carcel ;Else Charlotte Sandset ;Mariam Ali ;Maria Ignacia Allende EchanezMaria Giulia Mosconi<jats:p>This World Stroke Organization Scientific Statement highlights how sex and gender differences shape stroke risk, treatment, care, and research. Estrogen confers a relative protection before menopause, with risk increasing thereafter. Beyond shared cardiovascular determinants (hypertension, atrial fibrillation, and diabetes), women face sex-specific risks—hypertensive disorders of pregnancy, menopause, and hormone therapy, with clear implications for stroke prevention and management. Despite comparable efficacy of acute and secondary stroke therapies in women and men, women are less likely to receive timely acute treatment and often experience delays in recognition and access. The statement recommends gender-responsive prevention and care pathways; systematic consideration of pregnancy-related and menopausal factors; and public and professional education to improve stroke symptom recognition and purposeful inclusion of women across the research continuum. By integrating evidence from epidemiology, acute care, and secondary prevention, this statement provides clear and timely guidance for reducing inequities and shaping future research and policy to achieve equitable stroke care globally.</jats:p>1 - Some of the metrics are blocked by yourconsent settings
Item type:Publication, Dysphagia screening and risks of pneumonia and adverse outcomes after acute stroke: An international multicenter study(2020) ;Menglu Ouyang ;Elizabeth Boaden ;Hisatomi Arima ;Pablo M LavadosLaurent BillotDysphagia is associated with aspiration pneumonia after stroke. Data are limited on the influences of dysphagia screen and assessment in clinical practice. </jats:p></jats:sec><jats:sec><jats:title>Aims</jats:title><jats:p> To determine associations between a “brief” screen and “detailed” assessment of dysphagia on clinical outcomes in acute stroke patients. </jats:p></jats:sec><jats:sec><jats:title>Methods</jats:title><jats:p> A prospective cohort study analyzed retrospectively using data from a multicenter, cluster cross-over, randomized controlled trial (Head Positioning in Acute Stroke Trial [HeadPoST]) from 114 hospitals in nine countries. HeadPoST included 11,093 acute stroke patients randomized to lying-flat or sitting-up head positioning. Herein, we report predefined secondary analyses of the association of dysphagia screening and assessment and clinical outcomes of pneumonia and death or disability (modified Rankin scale 3–6) at 90 days. </jats:p></jats:sec><jats:sec><jats:title>Results</jats:title><jats:p> Overall, 8784 (79.2%) and 3917 (35.3%) patients were screened and assessed for dysphagia, respectively, but the frequency and timing for each varied widely across regions. Neither use of a screen nor an assessment for dysphagia was associated with the outcomes, but their results were compared to “screen-pass” patients, those who failed had higher risks of pneumonia (adjusted odds ratio [aOR] = 3.00, 95% confidence interval [CI] = 2.18–4.10) and death or disability (aOR = 1.66, 95% CI = 1.41–1.95). Similar results were evidence for the results of an assessment for dysphagia. Subsequent feeding restrictions were related to higher risk of pneumonia in patients failed dysphagia screen or assessment (aOR = 4.06, 95% CI = 1.72–9.54). </jats:p></jats:sec><jats:sec><jats:title>Conclusions</jats:title><jats:p> Failing a dysphagia screen is associated with increased risks of pneumonia and poor clinical outcome after acute stroke. Further studies concentrate on determining the effective subsequent feeding actions are needed to improve patient outcomes.1Scopus© Citations 46