LAVADOS GERMAIN, PABLO MANUEL
Preferred name
LAVADOS GERMAIN, PABLO MANUEL
Main Affiliation
Email
p.lavados@udd.cl
ORCID
0000-0002-9118-9093
Scopus Author ID
57188955599
153 results
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Item type:Publication, Abstract P84: Covid-19 and Stroke in the Latin American Stroke Registry (LASE)(2021)2 - Some of the metrics are blocked by yourconsent settings
Item type:Publication, REGIONAL DIFFERENCES IN EARLY BP MANAGEMENT AFTER ACUTE STROKE IN INTERNATIONAL RANDOMIZED CONTROLLED TRIALS OF 5000 PATIENTS 1 of 1 REGIONAL DIFFERENCES IN EARLY BP MANAGEMENT AFTER ACUTE STROKE IN INTERNATIONAL RANDOMIZED CONTROLLED TRIALS OF 5000 PATIENTS(2020); 12 - Some of the metrics are blocked by yourconsent settings
Item type:Publication, Stroke in Latin America: A systematic review of the incidence, prevalence and case-fatality between 1997-2021(2022); ; 6 - Some of the metrics are blocked by yourconsent settings
Item type:Publication, 1 - Some of the metrics are blocked by yourconsent settings
Item type:Publication, Epidemiology and risk factors of stroke in the Americas: a comprehensive narrative literature review(Elsevier BV, 2026-06)3Scopus© Citations 1 - Some of the metrics are blocked by yourconsent settings
Item type:Publication, Optimal achieved blood pressure in acute intracerebral hemorrhage INTERACT2(2015)13Scopus© Citations 89 - Some of the metrics are blocked by yourconsent settings
Item type:Publication, Scopus© Citations 2410 1 - Some of the metrics are blocked by yourconsent settings
Item type:Publication, WHY DO CHINESE PATIENTS HAVE BETTER OUTCOME AFTER ICH? INTERACT2 RESULTS(2021); 1 - Some of the metrics are blocked by yourconsent settings
Item type:Publication, Validation of transcranial Doppler in the diagnosis of brain death(2010-04); ; ; Roldán, Andrés1 - Some of the metrics are blocked by yourconsent settings
Item type:Publication, Patient centered outcomes in stroke: utility-weighted modified Rankin Scale results in a community-based study(Frontiers Media SA, 2025-03-21); ; Background and aims</jats:title><jats:p>The transformation of modified Rankin Scale (mRS) scores based on the corresponding utilities of health-related quality of life questionnaires can facilitate the capture of Patient-Centered Outcomes (PCO) in stroke. We aimed to derive utility-weighted modified Rankin Scale (UW-mRS) values by mapping mRS functional status to EQ-5D-3L scores in a population-based cohort of stroke patients.</jats:p></jats:sec><jats:sec><jats:title>Methods</jats:title><jats:p>The UW-mRS was obtained by analyzing the EQ5-D-3 L and mRS scores at 180 days after any stroke in the ÑANDU study, a large prospective community-based study in Chile. The mRS prediction was estimated using a linear regression adjusted by the EQ-5D-3L value. Generalized linear and binary logistic regression models were constructed to determine influencing factors of the UW-mRS, using STATA software (version 18.0).</jats:p></jats:sec><jats:sec><jats:title>Results</jats:title><jats:p>We included 773 patients presenting with any stroke during 2015–2016: 48% were female, with a mean age of 71 years (SD 13.8), and 85% had an acute ischemic stroke (AIS). 82% of patients had a low socioeconomic status, 50% had less than 12 years of formal education, and only 32% lived in urban areas. UW-mRS values for mRS categories 0–6 at 180 days were 0.913, 0.694, 0.425, 0.249, −0.102, −0.347 and 0, respectively. Multivariable analysis identified age &gt; 70 years (Coefficient <jats:italic>β</jats:italic> [β] -0.038 [Standard error SE 0.018], <jats:italic>p</jats:italic> = 0.032), prior mRS score 3–5 (<jats:italic>β</jats:italic> −0.556 [SE 0.197], <jats:italic>p</jats:italic> &lt; 0.001), ischemic stroke (β −0.066 [SE 0.025], <jats:italic>p</jats:italic> = 0.010), and National Institutes of Health Stroke Scale (NIHSS) at admission&gt;5 (<jats:italic>β</jats:italic> −0.015 [SE 0.002], <jats:italic>p</jats:italic> &lt; 0.001) as significant predictors of worse UW-mRS scores (R<jats:sup>2</jats:sup> = 70%) in the overall group. Sex-disaggregated analysis showed that age &gt; 70 years was a significant predictor in males (β −0.069 [SE 0.024], <jats:italic>p</jats:italic> = 0.006), while presenting an AIS had a greater impact on female’s worse UW-mRS score (β −0.087 [SE 0.033], <jats:italic>p</jats:italic> = 0.010).</jats:p></jats:sec><jats:sec><jats:title>Conclusion</jats:title><jats:p>These results present UW-mRS values derived from a population-based stroke study. Key determinants of health-related quality of life in post-stroke patients included age, prior disability, and stroke severity. Sex-disaggregated analysis revealed age being significant for males and AIS for females. Incorporating PCO as UW-mRS in stroke research can provide a more nuanced understanding of the impact of stroke on survivors, offering valuable insights for clinical decision-making and rehabilitation strategies across diverse healthcare contexts.<Scopus© Citations 1 6