STECHER GUZMAN, XIMENA PATRICIA
Preferred name
STECHER GUZMAN, XIMENA PATRICIA
Main Affiliation
Email
xstecher@udd.cl
ORCID
0000-0002-7962-9519
Scopus Author ID
56394442700
27 results
Now showing 1 - 10 of 27
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Item type:Product, Dataset - Coupling between neural oscillations and white matter integrity reveals cognitive computational profiles following COVID-19(OpenEuro, 2026); ; ;MATÍAS IRIARTE CARTER ;VÍCTOR MÁRQUEZMARIA PAZ DE LOS ANGELES MARTINEZ MOLINA - Some of the metrics are blocked by yourconsent settings
Item type:Publication, STatin TReatment for COVID-19 to Optimise NeuroloGical recovERy (STRONGER): study protocol for a randomised, open label clinical trial in patients with persistent neurological symptoms after COVID-19 infection(BMJ, 2025-04) ;Carlos Delfino ;Cheryl Carcel ;Xiaolei Lin; Sharon L Naismith<jats:sec> <jats:title>Introduction</jats:title> <jats:p>Increasing awareness of the high frequency, wide spectrum and disabling nature of symptoms that can persist following COVID-19 infection has prompted the investigation of management strategies. Our study aims to determine the effectiveness of atorvastatin on cognitive function, physical activity, mood, health-related quality of life and features of neurovascular impairment and neuroinflammation in adults with ongoing neurological symptoms after COVID-19 infection.</jats:p> </jats:sec> <jats:sec> <jats:title>Methods and analysis</jats:title> <jats:p>The STatin TReatment for COVID-19 to Optimise NeuroloGical recovERy study is an ongoing international, investigator-initiated and conducted, multicentre, prospective, randomised, open label, blinded endpoint trial with fixed time points for outcome assessments. A total of 410 participants with long covid neurological symptoms were planned to be randomly assigned to either the intervention group to receive 40 mg atorvastatin for 12 months or to a control group of no treatment, on top of usual care.</jats:p> </jats:sec> <jats:sec> <jats:title>Ethics and dissemination</jats:title> <jats:p>This study protocol was designed, implemented and reported, in accordance with the International Conference on Harmonisation guidelines for Good Clinical Practice, the National Health and Medical Research Council of Australia, the National Statement on Ethical Conduct in Human Research and with the ethical principles laid down in the World Medical Association Declaration of Helsinki. Central ethics committee approval was obtained from Sydney Local Health District Royal Prince Alfred Hospital Ethics (No: X21-0113 and 2021/ETH00777 10) in Australia. Site-specific ethics committee approvals were obtained elsewhere before any local study activities. All participants provided written informed consent.</jats:p> </jats:sec> <jats:sec> <jats:title>Trial registration number</jats:title> <jats:p>The study protocol is registered at Clinicaltrials.gov (<jats:ext-link xmlns:xlink="http://www.w3.org/1999/xlink" ext-link-type="clintrialgov" xlink:href="NCT04904536">NCT04904536</jats:ext-link>).</jats:p> </jats:sec>3 - Some of the metrics are blocked by yourconsent settings
Item type:Product, Dataset - White matter volume and microstructural integrity are associated with fatigue in relapsing multiple sclerosis(GITHUB, 2025) ;FIGUEROA VARGAS, ALEJANDRA; ; ; PAULO CESAR FIGUEROA TAIBA1 - Some of the metrics are blocked by yourconsent settings
Item type:Publication, A novel ITPA variant causes epileptic encephalopathy with multiple-organ dysfunction(2020) ;Masamune Sakamoto ;Den Kouhei ;Muzhirah Haniffa ;Sebastián SilvaMónica Troncoso9Scopus© Citations 16 - Some of the metrics are blocked by yourconsent settings
Item type:Publication, Neonatal brain microstructure correlates of neurodevelopment and gait in preterm children 18-22 mo of age: an MRI and DTI study(2015) ;Irene T. Ma ;Suzanne McConaghy ;Kopperuncholan Namachivayam ;Brian A. HalloranAshish R. KurundkarScopus© Citations 46 1 - Some of the metrics are blocked by yourconsent settings
Item type:Publication, Lateral Prefrontal Theta Oscillations Reflect Proactive Cognitive Control Impairment in Males With Attention Deficit Hyperactivity Disorder(2020) ;Francisco Zamorano ;Leonie Kausel ;ALBORNOZ, CARLOS ;Claudio LavinScopus© Citations 11 2 - Some of the metrics are blocked by yourconsent settings
Item type:Publication, RM de encéfalo sin anestesia en pacientes recién nacidos: Experiencia inicial en Clínica Alemana de Santiago(2014) ;Nicolás Sánchez D ;María Francesca Castoldi LScopus© Citations 2 1 - Some of the metrics are blocked by yourconsent settings
Item type:Publication, Lateral prefrontal activity as a compensatory strategy for deficits of cortical processing in Attention Deficit Hyperactivity Disorder(2017-12-01) ;ZAMORANO MENDIETA, FRANCISCO JAVIER; ;Kausel, Leonie ;Larrain, JosefinaAttention Deficit Hyperactivity Disorder (ADHD) is the most common neuropsychiatric disorder in childhood and is characterized by a delay of cortical maturation in frontal regions. In order to investigate interference control, which is a key function of frontal areas, a functional MRI study was conducted on 17 ADHD boys and 17 typically developing (TD) boys, while solving the multi source interference task (MSIT). This task consists of two conditions, a "congruent condition" and an "incongruent condition". The latter requires to inhibit information that interferes with task-relevant stimuli. Behavioral results showed that ADHD subjects committed more errors than TD children. In addition, TD children presented a larger MSIT effect -A greater difference in reaction times between the incongruent and the congruent conditions- than ADHD children. Associated to the MSIT effect, neuroimaging results showed a significant enhancement in the activation of the right lateral prefrontal cortex (rlPFC) in ADHD than in TD subjects. Finally, ADHD subjects presented greater functional connectivity between rlPFC and bilateral orbitofrontal cortex than the TD group. This difference in connectivity correlated with worse performance in both groups. Our results could reflect a compensatory strategy of ADHD children resulting from their effort to maintain an adequate performance during MSIT.3Scopus© Citations 15 - Some of the metrics are blocked by yourconsent settings
Item type:Product, Dataset - Patients recovering from COVID-19 who presented with anosmia during their acute episode have behavioral, functional, and structural brain alterations(OpenNeuro, 2024) ;LEONIE MARGARITA KAUSEL KAMP; ; ; 4 - Some of the metrics are blocked by yourconsent settings
Item type:Publication, White matter volume and microstructural integrity are associated with fatigue in relapsing multiple sclerosis(Springer Science and Business Media LLC, 2025-05-12); ;Sebastián Navarrete-Caro ;Claudia Cárcamo ;Ethel CiampiMacarena Vásquez-Torres10
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