MATURANA PEREA, ANDRES

Preferred name
MATURANA PEREA, ANDRES
Main Affiliation
Email
amaturana@udd.cl
ORCID
0000-0002-9219-9146
Scopus Author ID
57205356806

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    Economic evaluation of HIV screening in pregnant women attending antenatal clinics in India
    (2006-07-01)
    Kumar, Manoj
    ;
    Birch, Stephen
    ;
    MATURANA PEREA, ANDRES  
    ;
    Gafni, Amiran
    Objective: With prevalence of HIV rising in pregnant women in India, pediatric HIV/AIDS is emerging as a public health problem. We evaluated the additional costs to the health care system and the additional health outcomes of introducing a voluntary primary care HIV screening program for pregnant women in India. Methods: The analysis was conducted from the government perspective. We analyzed two scenarios: a programme of universal screening nation-wide and a programme of screening restricted to high prevalence states. Health benefits were measured by the number of perinatal HIV cases prevented and the reduction in the potential years of life lost (PYLL). Findings: Nation-wide screening would cost the government Rs. 254.78 million and would prevent 9880 cases of perinatal HIV resulting in savings of 131,700 life years (average cost per HIV case prevented Rs. 25,787; per year reduction in PYLLs Rs. 1935). Implementing the program in only the high prevalence states would achieve 45% of these reductions in cases and life years lost at only 20% of this cost, at an average of Rs. 12,091 per HIV case prevented or Rs. 907 per year reduction in PYLLs (44 Indian rupees = US$ 1). In sensitivity analysis, the cost of the program was influenced mainly by antenatal coverage, the cost of the HIV test, the lifetime costs of treatment of a HIV infected child and the overhead costs. Conclusions: We provide an estimate of the additional costs and health effects of two approaches to introducing HIV screening among pregnant women in India. Decision-makers would have to demonstrate that the resources used for its implementation would result in more health benefits than from the alternative uses of those resources. © 2005 Elsevier Ireland Ltd. All rights reserved.
      8Scopus© Citations 12
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    Profesionalismo y auto cuidado de los residentes, ¿cómo debemos enfocar su formación?
    (2021)
    Carla Benaglio
    ;
    MATURANA PEREA, ANDRES  
    ;
    Luigina Mortari
    ;
    Arnoldo Riquelme
    <jats:p>El profesionalismo es una competencia bien definida en la educación de los residentes, sin embargo, es un constructo complejo, sensible a variables sociales y culturales. Puede definirse como el nivel de destreza, buen juicio y comportamiento adecuado esperable de personas entrenadas para realizar bien su trabajo. Es una competencia que no se mantiene estable en el tiempo y decae cuando el profesional está sometido a altos niveles de estrés y se asocia a calidad de cuidado, educación, ética, moral, filosofía y humanismo. Es una competencia esencial en el profesional por lo cual debemos replantear los currículos para incluir formas de enseñar y evaluar el profesionalismo. Es fundamental pensar en programas que logren equilibrar la carga de trabajo con el bienestar de los futuros profesionales. Debemos generar un clima adecuado de aprendizaje donde el profesional en entrenamiento sea un protagonista activo, y el auto cuidado sea visibilizado como una competencia esencial para mantener el equilibrio entre la vida personal y profesional. Este articulo plantea una revisión y reflexión de este tema que cobra cada vez mas importancia en la formación de postgrado de futuros especialistas.</jats:p>
      22Scopus© Citations 1
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    Association of Cow's Milk Protein Allergy Prevalence With Socioeconomic Status in a Cohort of Chilean Infants
    (2020)
    María E. Arancibia
    ;
    LUCERO, YALDA  
    ;
    Isabel Miquel
    ;
    Pamela Marchant
    ;
    Lorena Rodriguez
      7  1Scopus© Citations 18
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    Animal-Derived Surfactants Versus Past and Current Synthetic Surfactants: Current Status
    (2007-03-01)
    Moya, Fernando
    ;
    MATURANA PEREA, ANDRES  
    In this review, the authors assess major outcomes resulting from head-to-head comparison trials of animal-derived surfactants with previous and newer synthetic surfactants and among them. They also pay special attention to issues of study design and quality of the trials reviewed. Animal-derived surfactants that contain surfactant proteins (Survanta, Infasurf, and Curosurf) perform clinically better than Exosurf, a synthetic surfactant containing only phospholipids, primarily in outcomes related to acute management of respiratory distress syndrome (RDS; faster weaning and pneumothorax) but not in overall mortality or incidence of bronchopulmonary dysplasia (BPD). Trials comparing various animal-derived surfactants that provide different amounts of surface protein B (SP-B) or phospholipids have shown minor differences in outcomes related to the management of RDS or none at all. The exception is the suggestion of better survival using a high initial dose of Curosurf when compared with Survanta. This observation is based on analysis of trials of relatively lesser quality that have included a smaller number of infants than other surfactant comparisons, however. Data from recent trials comparing a new-generation synthetic surfactant that contains a peptide mimicking the action of SP-B, Surfaxin, have shown that it performs better than Exosurf (faster weaning and less BPD) and at least as well as the animal-derived surfactants Survanta and Curosurf. The ideal surfactant comparison trial to demonstrate which surfactant is better has yet to be conducted. Future surfactant comparison trials should pay particular attention to study design, be appropriately sized, and include long-term follow-up. © 2007 Elsevier Inc. All rights reserved.
      6Scopus© Citations 42
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    Predictive Validity of Developmental Screening Questionnaires for Identifying Children With Later Cognitive or Educational Difficulties: A Systematic Review
    (2021)
    SCHONHAUT, LUISA  
    ;
    MATURANA PEREA, ANDRES  
    ;
    Olenkha Cepeda
    ;
    Pamela Serón
    <jats:p><jats:bold>Context:</jats:bold> Parent/caregiver completing developmental screening questionnaires (DSQs) for children before 5 years of age is currently recommended. The DSQs recommended by the American Academy of Pediatrics (AAP) are the Ages and Stages Questionnaires (ASQ), Parents' Evaluation of Developmental Status (PEDS), and the Survey of Well-being of Young Children (SWYC). Nevertheless, their predictive validity has not been well-established.</jats:p><jats:p><jats:bold>Objective:</jats:bold> To assess in the current literature, the value of AAP-recommended DSQs (ASQ, PEDS, SWYC) administered between 0 and 5 years of age, for predicting long-term cognitive achievement and/or school performance (CA/SP), after 1 year or more of evaluation and at/or after age 5 years, in the general population.</jats:p><jats:p><jats:bold>Data Sources:</jats:bold> Cochrane, MEDLINE PubMed, CINAHL, EMBASE, Web of Science, Scielo, and Scopus databases (until March 2021).</jats:p><jats:p><jats:bold>Study Selection:</jats:bold> Two authors selected the studies. Forward and backward citation follow-up was done; authors of DSQ were contacted to identify additional studies.</jats:p><jats:p><jats:bold>Data Extraction:</jats:bold> Cohorts were identified, and authors of selected studies were contacted to corroborate and complete extracted data.</jats:p><jats:p><jats:bold>Results:</jats:bold> Thirty-two publications, corresponding to 10 cohorts, were included. All cohorts used ASQ. Only cohort using PEDS was identified but did not meet the inclusion criteria. No cohorts conducted with SWYC were identified. Associations between ASQ and CA/SP were extracted for eight cohorts. The odds ratios were <jats:underline>&amp;gt;</jats:underline>3, and the area under the curve was 0.66–0.87. A trade-off between sensitivity and specificity was observed.</jats:p><jats:p><jats:bold>Limitations:</jats:bold> Heterogeneity in population characteristics and in DSQ adaptations.</jats:p><jats:p><jats:bold>Conclusions:</jats:bold> A positive association between ASQ and later CA/SP was found in different social, cultural, and economic settings. Additional studies are necessary to determine the impact factors in the predictive capacity of DSQs.</jats:p><jats:p><jats:bold>Systematic Review Registration:</jats:bold> PROSPERO, identifier: CRD42020183883.</jats:p>
    Scopus© Citations 8  1  1