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Item type:Publication, Cost-effectiveness of screening, decolonisation and isolation strategies for carbapenem-resistant Enterobacterales and methicillin-resistant Staphylococcus aureus infections in hospitals: a sex-stratified mathematical modelling study(Elsevier BV, 2025-03) ;Kasim Allel ;Patricia Garcia ;Anne Peters; Eduardo A. Undurraga2 - Some of the metrics are blocked by yourconsent settings
Item type:Publication, Gut Microbiota‐Derived Extracellular Vesicles Influence Alcohol Intake Preferences in Rats(Wiley, 2025-03) ;Macarena Díaz‐Ubilla ;Aliosha I. Figueroa‐Valdés ;Hugo E. Tobar ;María Elena QuintanillaEugenio Díaz<jats:title>ABSTRACT</jats:title><jats:p>Growing preclinical and clinical evidence suggests a link between gut microbiota dysbiosis and problematic alcohol consumption. Extracellular vesicles (EVs) are key mediators involved in bacteria‐to‐host communication. However, their potential role in mediating addictive behaviour remains unexplored. This study investigates the role of gut microbiota‐derived bacterial extracellular vesicles (bEVs) in driving high alcohol consumption. bEVs were isolated from the gut microbiota of a high alcohol‐drinking rat strain (UChB rats), either ethanol‐naïve or following chronic alcohol consumption and administered intraperitoneally or orally to alcohol‐rejecting male and female Wistar rats. Both types of UChB‐derived bEVs increased Wistar's voluntary alcohol consumption (three bottle choice test) up to 10‐fold (<jats:italic>p</jats:italic> < 0.0001), indicating that bEVs are able and sufficient to transmit drinking behaviour across different rat strains. Molecular analysis revealed that bEVs administration did not induce systemic or brain inflammation in the recipient animals, suggesting that the increased alcohol intake triggered by UChB‐derived bEVs operates through an inflammation‐independent mechanism. Furthermore, we demonstrate that the vagus nerve mediates the bEV‐induced increase in alcohol consumption, as bilateral vagotomy completely abolished the high drinking behaviour induced by both intraperitoneally injected and orally administered bEVs. Thus, this study identifies bEVs as a novel mechanism underlying gut microbiota‐induced high alcohol intake in a vagus nerve‐dependent manner.</jats:p>7 - Some of the metrics are blocked by yourconsent settings
Item type:Publication, Risk and impact of stroke across 38 countries and territories of the Americas from 1990 to 2021: a population-based trends analysis from the Global Burden of Disease Study 2021(Elsevier BV, 2025-03) ;Ramón Martinez; ;Pedro Ordunez ;Felipe FregniCarlos AbantoScopus© Citations 22 3 - Some of the metrics are blocked by yourconsent settings
Item type:Publication, Rethinking the Schenck Classification for Multiligament Knee Injuries: Evaluating Whether the Schenck KD Grade Is Associated With the Presence of Vascular or Neurological Injuries in a Multicenter Study With 144 Patients(SAGE Publications, 2025-03) ;Enrique Sanchez-Munoz ;Beatriz Lozano Hernanz ;Renato Andrade ;Cristina ValenteJoão Espregueira-MendesScopus© Citations 2 1 - Some of the metrics are blocked by yourconsent settings
Item type:Publication, Early developmental screening tools constructed in Latin American countries: umbrella review(Publicidad Permanyer, SLU, 2025-04-09); ;Antonia Valdés ;Ilan Oppenheimer ;Antonio Rizzoli-CórdobaRolando Rivera2Scopus© Citations 2 - Some of the metrics are blocked by yourconsent settings
Item type:Publication, Safety and efficacy of low-intensity versus standard monitoring following intravenous thrombolytic treatment in patients with acute ischaemic stroke (OPTIMISTmain): an international, pragmatic, stepped-wedge, cluster-randomised, controlled non-inferiority trial(Elsevier BV, 2025-05) ;Craig S Anderson ;Debbie Summers ;Menglu Ouyang ;Yi SuiBrenda Johnson2Scopus© Citations 15 - Some of the metrics are blocked by yourconsent settings
Item type:Publication, Polygenic score analysis identifies distinct genetic risk profiles in Alzheimer’s disease comorbidities(Springer Science and Business Media LLC, 2025-04-03) ;Carlos F. Hernández ;Camilo Villaman ;Costin Leu ;Dennis LalIgnacio Mata4 - Some of the metrics are blocked by yourconsent settings
Item type:Publication, Efficacy of platelet-rich-fibrin for the treatment of alveolar osteitis: a systematic review and meta-analysis(Medicina Oral, S.L., 2025) ;C. Ávila-Oliver ;V. Veloso ;G. Laissle ;AM. RojasF. Verdugo-Paiva2 - Some of the metrics are blocked by yourconsent settings
Item type:Publication, Getting long-term oxygen therapy right(Elsevier BV, 2025-06) ;Masooma Aqeel; ;Ayham Daher ;Mike HessChidiamara Maria NjokuScopus© Citations 1 2 - Some of the metrics are blocked by yourconsent settings
Item type:Publication, Cáncer de vesícula: ¿Es momento de modificar el GES?(SciELO Agencia Nacional de Investigacion y Desarrollo (ANID), 2024-10) ;Camila P. Samaniego ;Xabier de Aretxabala ;Felipe Castillo ;Álvaro ParedesM. Trinidad González14