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    EFFECTIVENESS AND SAFETY OF THE TETRAVALENT TAK-003 DENGUE VACCINE: A SYSTEMATIC REVIEW
    (2024)
    Ramos-rojas José
    ;
    Bengolea, Agustin
    ;
    Scigliano, Clara
    ;
    ;
    Catalano Hugo N.
      1
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    Early developmental screening tools constructed in Latin American countries: umbrella review
    (Publicidad Permanyer, SLU, 2025-04-09) ;
    Antonia Valdés
    ;
    Ilan Oppenheimer
    ;
    Antonio Rizzoli-Córdoba
    ;
    Rolando Rivera
      2Scopus© Citations 2
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    The Presence of Associated Injuries in Pediatric Radial Neck Fractures: A Systematic Review of the Literature and Meta-Analysis of Pooled Individual Patient Data
    (MDPI AG, 2025-02-27)
    Lisette C. Langenberg
    ;
    Joyce L. Benner
    ;
    ;
    Christiaan J. A. van Bergen
    ;
    Joost W. Colaris
    <jats:p>Background: Pediatric radial neck fractures (pRNFs) can occur in isolation or in association with concomitant injuries. It is unknown whether the presence of associated injuries should influence the choice of treatment. The aim of this study is to assess the incidence of associated injuries in pRNF and their correlation with fracture angulation (Judet grade) or the patient’s age (under or over ten years of age). Methods: A systematic literature review was performed following PRISMA-IPD guidelines, including case series on pRNF with a minimum of five cases of children until 16 years of age. The quality assessment included a risk of bias analysis and evaluation using the MINORS criteria. Individual patient data on age, Judet classification and associated injuries were extracted from the included studies and pooled for the meta-analysis. The correlation between the presence of associated injury and the patient’s age or Judet classification was depicted in two forest plots. Results: A total of 20 articles published sufficient individual patient data (n = 371) on associated injuries. All but one were retrospective case series. Fifteen articles had MINORS scores of 8 or higher. The incidence of associated injuries was 33% (123 of 371 cases). Almost half of the associated injuries included an olecranon fracture (61/123). There was no correlation between Judet classification (p = 0.243) and incidence nor between patient age and the incidence of associated injuries (p = 0.694). Conclusions: Surgeons should be aware of potential associated injuries in over a third of pRNF cases, regardless of the patient’s age or fracture angulation. Deduction of the trauma mechanism may be a more useful tool for assessing the potential presence of associated injuries than the most frequently used fracture classification or the patient’s age. More research is needed regarding the requirements for enhanced diagnostic imaging, specific treatment or follow-up adaptations in children with pRNFs and associated injuries.</jats:p>
      4Scopus© Citations 1
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    Instruments for Measuring Hedonic and Eudaimonic Well-Being of Adolescents in the Latin American School Contexts: a Systematic Review
    (Springer Science and Business Media LLC, 2025-03-10)
    Mónica Bravo-Sanzana
    ;
    Ferran Casas
    ;
    Matías E. Rodríguez-Rivas
    ;
    Xavier Oriol
    ;
      3
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    A Systematic Literature Review on the Use of Clays for Arsenic Removal
    (MDPI AG, 2025-05-07)
    Lorenzo Reyes-Bozo
    ;
    Eduardo Vyhmeister
    ;
    Gabriel G. Castane
    ;
    Juan Chirinos
    ;
    Jeannette Zárraga
    Arsenic contamination in water remains a critical global challenge, particularly in rural and resource-limited regions. Clays have been widely studied as cost-effective and efficient adsorbents for arsenic removal. This systematic review provides a comprehensive analysis of the application of clays in arsenic adsorption, focusing on clay types, operational units, and study methodologies. The review classifies the adsorption mechanisms, highlights key factors influencing adsorption performance—such as pH, ionic strength, and surface modifications—and examines the effectiveness of various modifications. Furthermore, the study categorizes adsorption research into kinetic, iso-thermal, thermodynamic, and efficiency studies, providing insights into the state of the art and the experimental conditions that govern arsenic removal. It also discusses the scalability and practical application of clay-based adsorption technologies, emphasizing gaps in field validation, regeneration studies, and large-scale implementation. The findings highlight the potential of natural and modified clays in arsenic remediation, while underscoring the need for further research to optimize adsorption conditions and enhance sustainability in water treatment systems.
      2
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    Efficacy of platelet-rich-fibrin for the treatment of alveolar osteitis: a systematic review and meta-analysis
    (Medicina Oral, S.L., 2025)
    C. Ávila-Oliver
    ;
    V. Veloso
    ;
    G. Laissle
    ;
    AM. Rojas
    ;
    F. Verdugo-Paiva
      2
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    Early high-sensitivity troponin elevation and short-term mortality in sepsis: a systematic review with meta-analysis
    (Springer Science and Business Media LLC, 2025-02-14)
    Abraham I. J. Gajardo
    ;
    Santiago Ferrière-Steinert
    ;
    Joaquín Valenzuela Jiménez
    ;
    Sebastián Heskia Araya
    ;
    Thomas Kouyoumdjian Carvajal
    Abstract Background Serum cardiac troponin (cTn) elevation is a well-established phenomenon in sepsis. However, the clinical signifcance of this phenomenon with high-sensitivity (hs) assays and the current sepsis defnition needs to be settled. Research Question What is the association between early serum cTn levels measured by hs-assays and the risk of short-term mortality in septic patients? Study Design and Methods We conducted a systematic review using a comprehensive PubMed, Scopus, and Embase search. Studies were eligible if they reported association data on early hs-cTn and mortality in an adult sample with sepsis that met the Sepsis-3 defnition. For the synthesis of the efect of hs-cTn on mortality, we applied random efect models on the pooled unadjusted and adjusted odds ratio (OR and aOR, respectively) of elevated vs. normal hs-cTn serum values, and on the crude standardized mean diference (SMD) of hs-cTn between survivors and non-survivors. Results In total, 6242 patients from 17 studies were included, with short-term mortality rates ranging from 16.9% to 53.8%. Using a crude analysis, non-survivor patients showed higher hs-cTn than survivors (SMD of 0.87, 95%CI: 0.41–1.33). Elevated hs-cTn was associated with increased mortality (OR=1.78, 95% CI: 1.41–2.25). However, this prognostic efect was absent in studies that adjusted for diferent confounders (aOR=1.06, 95% CI: 0.99–1.14). Discussion and Conclusions Non-survivors of sepsis exhibited signifcantly elevated hs-cTn levels. While elevated hs-cTn levels are associated with an increased risk of mortality, they are not independently associated with this outcome in sepsis
      1Scopus© Citations 19
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    Conventional Radiotherapy Timing and Wound Complication Avoidance After Surgery for Metastatic Spine Disease. A LatAm Modified Delphi Study
    (Elsevier BV, 2025-03)
    Federico Landriel
    ;
    Kevin White
    ;
    Fernando Padilla Lichtenberger
    ;
    Alfredo Guiroy
    ;
    Alisson Teles
      2
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    Scopus© Citations 1  2