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    Women with polycystic ovary syndrome (PCOS): Likelihood of cooccurring neuropsychiatric conditions and the dual hit hypothesis
    (Elsevier BV, 2025-04)
    Juan Pablo Del Río
    ;
    Alexandros Tsompanidis
    ;
    Pablo A. Gaspar
    ;
    Alejandro Maturana-Hurtado
    ;
    Gonzalo M. Rojas-Costa
    Scopus© Citations 7  6
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    Oscillatory activity underlying cognitive performance in children and adolescents with autism: a systematic review
    (2024)
    SOTO ICAZA, PATRICIA  
    ;
    Patricio Soto-Fernández
    ;
    Leonie Kausel
    ;
    MÁRQUEZ RODRÍGUEZ, VÍCTOR JULIO  
    ;
    CARVAJAL PAREDES, PATRICIO ALEJANDRO  
    <jats:p>Autism spectrum disorder (ASD) is a neurodevelopmental condition that exhibits a widely heterogeneous range of social and cognitive symptoms. This feature has challenged a broad comprehension of this neurodevelopmental disorder and therapeutic efforts to address its difficulties. Current therapeutic strategies have focused primarily on treating behavioral symptoms rather than on brain psychophysiology. During the past years, the emergence of non-invasive brain stimulation techniques (NIBS) has opened alternatives to the design of potential combined treatments focused on the neurophysiopathology of neuropsychiatric disorders like ASD. Such interventions require identifying the key brain mechanisms underlying the symptomatology and cognitive features. Evidence has shown alterations in oscillatory features of the neural ensembles associated with cognitive functions in ASD. In this line, we elaborated a systematic revision of the evidence of alterations in brain oscillations that underlie key cognitive processes that have been shown to be affected in ASD during childhood and adolescence, namely, social cognition, attention, working memory, inhibitory control, and cognitive flexibility. This knowledge could contribute to developing therapies based on NIBS to improve these processes in populations with ASD.</jats:p>
      9Scopus© Citations 11
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    Towards a comprehensive approach to mentalization-based treatment for children with autism: integrating attachment, neurosciences, and mentalizing
    (2023)
    Stefanella Costa-Cordella
    ;
    SOTO ICAZA, PATRICIA  
    ;
    Karin Borgeaud
    ;
    Aitana Grasso-Cladera
    ;
    Norka T. Malberg
    Autism spectrum disorder (ASD) is diagnosed based on socio-communicative difficulties, which are believed to result from deficits in mentalizing, mainly evidenced by alterations in recognizing and responding to the mental states of others. In recent years, efforts have been made to develop mentalization-based treatment (MBT) models for this population. These models focus on enhancing individuals’ ability to understand and reflect on their own mental states, as well as those of others. However, MBT approaches for people with ASD are limited by their existing theoretical background, which lacks a strong foundation grounded in neuroscience-based evidence properly integrated with attachment, and mentalizing. These are crucial aspects for understanding psychological processes in autism, and as such, they play a pivotal role in shaping the development of tailored and effective therapeutic strategies for this specific population. In this paper we review evidence related to the neurobiological, interpersonal, and psychological dimensions of autism and their implications for mentalizing processes. We also review previous mentalization-based frameworks on the psychosis continuum to provide a comprehensive understanding of attachment, neurobiology, and mentalization domains in therapeutic approaches for autism. After presenting a synthesis of the literature, we offer a set of clinical strategies for the work with children with autism. Finally, we provide recommendations to advance the field towards more robust models that can serve as a basis for evidence-based therapeutic strategies.
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      1Scopus© Citations 6  1