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    Exploring the feasibility and effectiveness of a naturalistic family centered intervention to enhance early interactions in toddlers with Down syndrome
    (Springer Science and Business Media LLC, 2025-04-09)
    Ana Mendoza-García
    ;
    Andrés Aparicio
    ;
    Paulina Sofía Arango
    ;
    TENORIO DELGADO, MARCELA  
    This study analyses the feasibility and effectiveness of BabyMICARE, a manualised intervention programme aimed at improving the interactions between caregivers and infants and toddlers with Down syndrome. The programme’s goal is to enhance caregivers’ sensitivity and reduce directivity during early interactions, particularly during play and daily routines. A pre-test and post-test design was used with 40 dyads of infants with Down syndrome and their caregivers, who were divided into a control group (n = 20) and an intervention group (n = 20), based on baseline scores in key interaction subscales. Sessions were conducted over 10 weeks by trained psychologists. Parent-infant interaction was assessed using the MACI coding system, which measures aspects such as sensitive responsiveness, directivity and the level of reciprocity between the parent and the child. The programme showed high feasibility, with a 100% attendance rate but some rescheduling. Caregivers evaluated it positively. The intervention group demonstrated significant improvements in five of eight MACI scales, particularly in sensitive responsiveness and nondirectiveness, while no changes were observed in the control group. The results suggest that BabyMICARE is a feasible and effective intervention for promoting more responsive, less directive interactions, which may be crucial in fostering children’s development.
      3
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    Your baby has down syndrome: a reflexive thematic analysis of breaking the news to parents
    (Springer Science and Business Media LLC, 2025-05-06)
    TENORIO DELGADO, MARCELA  
    ;
    Johanna Sagner-Tapia
    ;
    Renata Garibaldi
    ;
    Vaso Totsika
    Scopus© Citations 1  6
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    Early parenting interventions to prevent internalising problems in children and adolescents: a global systematic review and network meta-analysis
    (2023)
    Ilaria Costantini
    ;
    José A López‐López
    ;
    Deborah Caldwell
    ;
    Amy Campbell
    ;
    Veronica Hadjipanayi
    <jats:sec><jats:title>Question</jats:title><jats:p>We compared the effectiveness of different types of parenting interventions based on an a priori taxonomy, and the impact of waitlists versus treatment as usual (TAU), in reducing child internalising problems.</jats:p></jats:sec><jats:sec><jats:title>Study selection and analysis</jats:title><jats:p>We conducted a systematic review and network meta-analysis of published and unpublished randomised controlled trials (RCTs) until 1 October 2022 that investigated parenting interventions with children younger than 4 years. Exclusion criteria: studies with children born preterm, with intellectual disabilities, or families receiving support for current abuse, neglect, and substance misuse. We assessed the certainty of evidence using the Confidence in Network Meta-Analysis framework. We used random-effects network meta-analysis to estimate standardised mean differences (SMDs) with 95% credible intervals (CrIs).</jats:p></jats:sec><jats:sec><jats:title>Findings</jats:title><jats:p>Of 20 520 citations identified, 59 RCTs (18 349 participants) were eligible for the network meta-analysis. Parenting interventions focusing on the dyadic relationship (SMD: −0.26, 95% CrI: −0.43 to −0.08) and those with mixed focus (−0.09, –0.17 to −0.02) were more effective in reducing internalising problems than TAU at the first time point available. All interventions were more effective than waitlist, which increased the risk of internalising problems compared with TAU (0.36, 0.19 to 0.52). All effects attenuated at later follow-ups. Most studies were rated as with ‘high risk’ or ‘some concerns’ using the Risk of Bias Assessment Tool V.2. There was no strong evidence of effect modification by theoretically informed components or modifiers.</jats:p></jats:sec><jats:sec><jats:title>Conclusions</jats:title><jats:p>We found preliminary evidence that relationship-focused and mixed parenting interventions were effective in reducing child internalising problems, and the waitlist comparator increased internalising problems with implications for waiting times between referral and support. Considering the high risk of bias of most studies included, the findings from this meta-analysis should be interpreted with caution.</jats:p><jats:p><jats:bold>PROSPERO registration number</jats:bold>CRD42020172251.</jats:p></jats:sec>
      4Scopus© Citations 8
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    Trajectories of Parental Daily Stress: An Ecological Momentary Assessment Study during the COVID-19 Lockdown
    (2023)
    ALDONEY RAMIREZ, DANIELA  
    ;
    Andrés Muñoz-Najar
    ;
    COO CALCAGNI, SOLEDAD  
    ;
    PÉREZ EWERT, JANET CAROLA  
    ;
    Manuel Montemurro
    <jats:p>The COVID-19 pandemic was a source of significant stress due to health and safety concerns and measures to control the virus’ spread, such as mobility restrictions. This measure was especially demanding for parents with school aged children, who had to find new work–family balance as their children participate in online education while attempting to work remotely. To evaluate parents’ stress trajectories during the pandemic, we conducted Ecological Momentary Assessments (EMAs) during lockdown for 29 days in 68 families in Santiago, Chile. In addition, we evaluated the role of educational level and income, co-parenting, and number of children in parents’ stress trajectories. Our results showed that during the first weeks of lockdown expected protective factors (i.e., income and co-parental support) were not able to influence parents’ daily stress management. Moreover, parents with higher educational levels reported worse stress adaptation than less educated parents. On the other hand, co-parental conflict was significantly associated with parent’s stress. Our study captured an acute response to COVID-19 related challenges. This study contributes to understanding how parents adjust to stress during adverse circumstances such as the COVID-19 pandemic.</jats:p>
      18  1Scopus© Citations 2
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      1Scopus© Citations 10  1
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      8  1Scopus© Citations 17
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      25  1Scopus© Citations 21
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    Attention deficit hyperactivity disorder and its association with heavy metals in children from northern Chile
    (2020)
    María Pía Muñoz
    ;
    RUBILAR RAMIREZ, PAOLA  
    ;
    Macarena Valdés
    ;
    María Teresa Muñoz-Quezada
    ;
    Andrea Gómez
      5Scopus© Citations 38
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    Interacciones entre las madres y sus bebés prematuros moderados durante la hospitalización
    (2022)
    MIRA OLIVOS, ANDREA  
    ;
    COO CALCAGNI, SOLEDAD  
    ;
    Rodolfo Bastías
    ;
    Ricardo González
    <jats:p>Los recién nacidos prematuros moderados son fisiológicamente inmaduros, su cerebro tiene que madurar y adaptarse al entorno extrauterino, lo que puede afectar su desarrollo neurológico. La interacción con sus cuidadores es crucial para su desarrollo, no obstante, estos pueden evidenciar problemáticas de salud mental como sintomatología depresiva y estrés parental. Objetivo: evaluar cómo la sintomatología depresiva y la percepción del estrés de las madres de bebés prematuros moderados durante la hospitalización puede afectar la interacción de la díada. Pacientes y Método: participaron 85 díadas. Durante la segunda y tercera semana de hospitalización, las madres completaron un cuestionario sociodemográfico, la escala de estrés parental y la Edinburgh postnatal depression scale (EPDS). La interacción madre-hijo fue evaluada y codificada con la Escala de Observación del Vínculo Madre-Bebé Hospitalizados. Resultados: las madres de bebés prematuros moderados hospitalizados en una unidad de neonatología pueden presentar una importante sintomatología depresiva y ésta se correlaciona con el estrés experimentado por la madre. El estrés parental y el ser pequeño para la edad gestacional evidenciaron una asociación negativa con las interacciones de las diadas. Conclusiones: El tener un bebé prematuro moderado puede impactar la salud mental de las madres y esto a su vez se relaciona con las interacciones que tienen con sus hijos/as. Del mismo modo se detectaron variables relacionadas con los bebés que también pueden disminuir las interacciones y contacto entre la diada.</jats:p>
      1Scopus© Citations 2  1
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    Childhood adversity increases risk of psychotic experiences in patients with substance use disorder
    (2022)
    Ignacio Bórquez-Infante
    ;
    Javiera Vasquez
    ;
    Sofía Dupré
    ;
    Eduardo A. Undurraga
    ;
    Nicolás A. Crossley
    Scopus© Citations 10  4