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  4. 4-Hydroxynonenal induces Cx46 hemichannel inhibition through its carbonylation
Details

4-Hydroxynonenal induces Cx46 hemichannel inhibition through its carbonylation

Journal
Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids
ISSN
1388-1981
Date Issued
2020
Author(s)
Mauricio A. Retamal  
Facultad de Medicina Clínica Alemana Universidad del Desarrollo  
Mariana C. Fiori
Ainoa Fernandez-Olivares
Facultad de Medicina Clínica Alemana Universidad del Desarrollo  
Sergio Linsambarth
Francisca Peña
Daisy Quintana
Jimmy Stehberg
Guillermo A. Altenberg
Type
Resource Types::text::journal::journal article
Scopus ID
2-s2.0-85082962355
WoS ID
WOS:000537835800003
DOI
10.1016/j.bbalip.2020.158705
URL
https://investigadores.udd.cl/handle/123456789/5155
URL Institutional Repository
http://hdl.handle.net/11447/4144
Cite this document
Retamal, M. A., Fiori, M. C., Fernandez-Olivares, A., Linsambarth, S., Peña, F., Quintana, D., Stehberg, J., & Altenberg, G. A. (2020). 4-Hydroxynonenal induces Cx46 hemichannel inhibition through its carbonylation. Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids, 1865(8), 158705. https://doi.org/10.1016/j.bbalip.2020.158705
Project(s)
Carbon monoxide inhibits Cx46 HCs through a lipid peroxidation-dependent process which increases Cx46- Ca2+ sensitivity  
Subjects
carbonylation

; 

cataract

; 

connexin

; 

lipid peroxide

; 

post-translational modification

; 

aldehydes

; 

animals

; 

connexins

; 

hela cells

; 

humans

; 

protein carbonylation

; 

rats

; 

rats, sprague-dawley

; 

xenopus laevis

; 

4 hydroxynonenal

; 

connexin 46

; 

cysteine

; 

dithiothreitol

; 

green fluorescent protein

; 

4-hydroxy-2-nonenal

; 

aldehyde

; 

connexin 46

; 

gap junction protein

; 

animal cell

; 

animal experiment

; 

animal model

; 

article

; 

cataract

; 

controlled study

; 

female

; 

hela cell line

; 

human

; 

human cell

; 

immunoblotting

; 

nonhuman

; 

oocyte

; 

priority journal

; 

protein carbonylation

; 

protein expression

; 

rat

; 

xenopus laevis

; 

animal

; 

drug effect

; 

metabolism

; 

protein carbonylation

; 

sprague dawley rat
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