RUBILAR RAMIREZ, PAOLA ANDREA

Preferred name

Main Affiliation

Facultad de Medicina Clínica Alemana Universidad del Desarrollo

pramirez@udd.cl

ORCID

0000-0003-3578-459X

Scopus Author ID

57031794200

Goggle Scholar

https://scholar.google.com/citations?hl=es&user=rYIiQ2kAAAAJ

Now showing 1 - 10 of 24

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Dataset - From the Atacama to Patagonia: Understanding the Effects of Extreme Temperatures on Birth Weight Across Climate Regions in Chile
(GitHUB, 2025)
RUBILAR RAMIREZ, PAOLA ANDREA
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MATUTE WILLEMSEM, MARIA ISABEL
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Post-COVID-19 symptoms in a community sample: Exploratory study in two Chilean cities, 2023–2024
(Elsevier BV, 2025-11)
Xaviera Molina
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Camila Awad
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Muriel Ramírez-Santana
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RUBILAR RAMIREZ, PAOLA ANDREA
;
Loreto Nunez-Franz
1
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Overcoming Health Inequities: Spatial Analysis of Seroprevalence and Vaccination Against COVID-19 in Chile
(2024)
Muriel Ramírez-Santana
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Juan Correa
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Loreto Núñez Franz
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APABLAZA SALINAS, MAURICIO IVÁN
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RUBILAR RAMIREZ, PAOLA ANDREA
Scopus© Citations 1 6
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Seroprevalence, spatial distribution, and social determinants of SARS-CoV-2 in three urban centers of Chile
(2022)
VIAL CLARO, PABLO AGUSTIN
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GONZALEZ WIEDMAIER, CLAUDIA MARTA
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Gloria Icaza
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Muriel Ramirez-Santana
;
Rubén Quezada-Gaete
<jats:title>Abstract</jats:title><jats:sec> <jats:title>Background</jats:title> <jats:p>Seroprevalence studies provide an accurate measure of SARS-CoV-2 spread and the presence of asymptomatic cases. They also provide information on the uneven impact of the pandemic, pointing out vulnerable groups to prioritize which is particularly relevant in unequal societies. However, due to their high cost, they provide limited evidence of spatial spread of the pandemic specially in unequal societies. Our objective was to estimate the prevalence of SARS-CoV-2 antibodies in Chile and model its spatial risk distribution.</jats:p> </jats:sec><jats:sec> <jats:title>Methods</jats:title> <jats:p>During Oct–Nov 2020, we conducted a population-based serosurvey in Santiago, Talca, and Coquimbo–La Serena (2493 individuals). We explored the individual association between positive results and socio-economic and health-related variables by logistic regression for complex surveys. Then, using an Empirical Bayesian Kriging model, we estimated the infection risk spatial distribution using individual and census information, and compared these results with official records.</jats:p> </jats:sec><jats:sec> <jats:title>Results</jats:title> <jats:p>Seroprevalence was 10.4% (95% CI 7.8–13.7%), ranging from 2% (Talca) to 11% (Santiago), almost three times the number officially reported. Approximately 36% of these were asymptomatic, reaching 82% below 15 years old. Seroprevalence was associated with the city of residence, previous COVID-19 diagnosis, contact with confirmed cases (especially at household), and foreign nationality. The spatial model accurately interpolated the distribution of disease risk within the cities finding significant differences in the predicted probabilities of SARS-CoV-2 infection by census zone (IQR 2.5–15.0%), related to population density and education.</jats:p> </jats:sec><jats:sec> <jats:title>Conclusions</jats:title> <jats:p>Our results underscore the transmission heterogeneity of SARS-CoV-2 within and across three urban centers of Chile. Socio-economic factors and the outcomes of this seroprevalence study enable us to identify priority areas for intervention. Our methodological approach and results can help guide the design of interdisciplinary strategies for urban contexts, not only for SARS-CoV-2 but also for other communicable diseases.</jats:p> </jats:sec>
Scopus© Citations 11 1
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Dataset - Heat beyond percentiles: exploring preterm birth risks in Santiago, Chile (1991–2019)
(GITHUB, 2026)
RUBILAR RAMIREZ, PAOLA ANDREA
1
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Dataset - Immunization and SARS-CoV-2 Antibody Seroprevalence in a Country with High Vaccination Coverage: Lessons from Chile
(ZENODO, 2022)
AGUILERA SANHUEZA, XIMENA PAZ
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GONZALEZ WIEDMAIER, CLAUDIA MARTA
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APABLAZA SALINAS, MAURICIO IVÁN
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RUBILAR RAMIREZ, PAOLA ANDREA
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CORTES SALINAS, LINA JIMENA
10
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HIGH VULNERABILITY AND LOW MENTAL WELL-BEING: EVIDENCE FROM A COMMUNITY SURVEY FOR PRIMARY HEALTH CARE MANAGEMENT
(2025)
RUBILAR RAMIREZ, PAOLA ANDREA
1
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Heat beyond percentiles: exploring preterm birth risks in Santiago, Chile (1991–2019)
(Springer Science and Business Media LLC, 2025-12-26)
Estela Blanco
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José Daniel Conejeros
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Álvaro González-Reyes
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RUBILAR RAMIREZ, PAOLA ANDREA
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Pablo Sarricolea
2
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From the Atacama to Patagonia: Understanding the Effects of Extreme Temperatures on Birth Weight Across Climate Regions in Chile
(American Geophysical Union (AGU), 2025-12)
E. Blanco
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J. D. Conejeros
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RUBILAR RAMIREZ, PAOLA ANDREA
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R. Jiménez
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P. Guiñez
<jats:title>Abstract</jats:title> <jats:p>Exposure to extreme temperatures during pregnancy can have adverse effects on birth weight, however, there is little evidence from Latin America. We used birth records in 2011–2020. Mean, minimum, and maximum daily temperatures were obtained from meteorological stations in 26 municipalities representing different climatic zones of Chile. We explored different windows of exposure (entire pregnancy, trimester, and gestational week) and calculated temperature percentiles based on climatic zone for each window. The 50th percentile served as the reference for comparison. General additive models and distributed lag nonlinear models (DLNM) adjusted for month and year of last menstrual cycle, maternal and paternal: age, education, and employment. Exposure to cold mean temperatures (≤10th percentile) in the total pregnancy period and each trimester was associated with a lower mean birth weight (−28.7 g for the total period, −45.9, −36.1, and −83.4 g for trimester 1, 2, and 3, respectively), whereas exposure to warm mean temperatures was associated with higher birth weight (21.3 g for >90th percentile). For extreme temperatures, exposure to both cold (≤10th percentile for minimum) and hot (>90th percentile for maximum) in the total pregnancy period related to lower birth weight: −48.7 g (95% CI −49.7; −47.6) and −17.48 g (95% CI −18.5; −16.4), respectively, with similar effects by trimester. In DLNM, consistent effects were observed later in pregnancy. Lower birthweight was observed with exposure to extreme cold and heat, while warmer mean temperatures were associated with higher birthweight. Findings from Chile underscore regional impacts of climate change on child health.</jats:p>
2
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Seroprevalence of Natural and Acquired Immunity against the SARS-CoV-2 Virus in a Population Cohort from Two Chilean Cities, 2020–2022
(2023)
Loreto Núñez-Franz
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Muriel Ramírez-Santana
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RUBILAR RAMIREZ, PAOLA
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Macarena Said
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VIAL COX, MARIA CECILIA
<jats:p>Background: Chile has achieved the highest coverage for vaccines against the SARS-CoV-2 virus worldwide. Objective: To assess the progression of immunity (natural and acquired by vaccine) in a cohort from two Chilean cities. Methods: Individuals (n = 386) who participated in three phases of population-based serial prevalence studies were included (2020–2021 and 2022). Presence of SARS-CoV-2 antibodies was measured in serum. Data including time of vaccination and type of vaccine received were analysed with descriptive statistics. Results: Seroprevalence was 3.6% in the first round and increased to 96.9% in the second and 98.7% in the third. In the third round, 75% of individuals who had received the basal full scheme were seropositive at 180 days or more since their last dose; 98% of individuals who received one booster dose were seropositive at 180 days or more, and 100% participants who received two boosters were seropositive, regardless of time since their last dose. Participants receiving mRNA vaccines had higher seroprevalence rates over time. Conclusions: The high vaccination coverage in Chile enabled the population to maintain high levels of antibodies. Vaccination boosters are essential to maintain immunity over time, which also depends on the type of vaccine administered.</jats:p>
1Scopus© Citations 12

RUBILAR RAMIREZ, PAOLA ANDREA

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