PALISSON ETCHARREN, FRANCIS
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PALISSON ETCHARREN, FRANCIS
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PALISSON ETCHARREN, FRANCIS
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fpalisson@udd.cl
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18037973900

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IMMUNE CELL PROFILING OF WOUNDS FROM EPIDERMOLYSIS BULLOSA PATIENTS

2020 , YUBERO GONCALVEZ, MARIA JOAO , FUENTES BUSTOS, MARIA IGNACIA , PALISSON ETCHARREN, FRANCIS , REBOLLEDO JARAMILLO, BORIS EDUARDO , Guttmann-Gruber, Christina , Tockner, Birgit , Anja Diem , Klausegger, Alfred , Cofre-Araneda, Glenda , Figuera, Olga , Hidalgo, Yessia , Morande, Pilar , Cho, Raymond J. , Rishel, Heather I , Marinkovich, M. Peter , Teng, Joyce , Webster, Timothy G. , Prisco, Marco , Eraso, Luis H. , Hofbauer, Josefina Pinon , South, Andrew P.

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Cells from discarded dressings differentiate chronic from acute wounds in patients with Epidermolysis Bullosa

2020 , FUENTES BUSTOS, MARIA IGNACIA , Christina Guttmann-Gruber , Birgit Tockner , Anja Diem , Alfred Klausegger , Glenda Cofré-Araneda , Olga Figuera , Yessia Hidalgo , Pilar Morandé , PALISSON ETCHARREN, FRANCIS , Boris Rebolledo-Jaramillo , YUBERO GONCALVEZ, MARIA JOAO , Raymond J. Cho , Heather I. Rishel , M. Peter Marinkovich , Joyce M. C. Teng , Timothy G. Webster , Marco Prisco , Luis H. Eraso , Josefina Piñon Hofbauer , Andrew P. South

AbstractImpaired wound healing complicates a wide range of diseases and represents a major cost to healthcare systems. Here we describe the use of discarded wound dressings as a novel, cost effective, accessible, and non-invasive method of isolating viable human cells present at the site of skin wounds. By analyzing 133 discarded wound dressings from 51 patients with the inherited skin-blistering disease epidermolysis bullosa (EB), we show that large numbers of cells, often in excess of 100 million per day, continually infiltrate wound dressings. We show, that the method is able to differentiate chronic from acute wounds, identifying significant increases in granulocytes in chronic wounds, and we show that patients with the junctional form of EB have significantly more cells infiltrating their wounds compared with patients with recessive dystrophic EB. Finally, we identify subsets of granulocytes and T lymphocytes present in all wounds paving the way for single cell profiling of innate and adaptive immune cells with relevance to wound pathologies. In summary, our study delineates findings in EB that have potential relevance for all chronic wounds, and presents a method of cellular isolation that has wide reaching clinical application.

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Corrigendum to “Novel and recurrent COL7A1 mutations in Chilean patients with dystrophic epidermolysis bullosa” [J. Dermatol. Sci. 65 (2012) 149–152]

2012 , Rodrígueza, Fernando A. , Gana, María José , Yubero, María Joao , Close Zillmann, Gisela , Kramer, Susanne M. , Catalána, Javiera , Rubio-Astudillo, Julia , González, Sergio , Liu, Lu , Ozoemena, Linda , Mellerio, Jemima E. , McGrath, John A. , PALISSON ETCHARREN, FRANCIS , CONGET MOLINA, PAULETTE ANDREA

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Life-Threatening Complications Following Orthognathic Surgery in a Patient With Undiagnosed Hereditary Angioedema

2013 , Julio Cifuentes , Francis Palisson , Salvador Valladares , Daniel Jerez

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End Stage Renal Disease in a Child with Epidermolysis Bullosa

2016 , CARLOS FELIPE GONZALO CAVAGNARO SANTA MARIA , María Joao Yubero , Marcela Valenzuela , Francis Palisson

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APOBEC mutation drives early-onset squamous cell carcinomas in recessive dystrophic epidermolysis bullosa

2018 , Raymond J. Cho , Ludmil B. Alexandrov , Nicoline Y. den Breems , Velina S. Atanasova , Mehdi Farshchian , Elizabeth Purdom , Tran N. Nguyen , Cristian Coarfa , Kimal Rajapakshe , Marco Prisco , Joya Sahu , Patrick Tassone , Evan J. Greenawalt , Eric A. Collisson , Wei Wu , Hui Yao , Xiaoping Su , Christina Guttmann-Gruber , Josefina Piñón Hofbauer , Raabia Hashmi , Ignacia Fuentes , Stephen C. Benz , Justin Golovato , Erik A. Ehli , Christel M. Davis , Gareth E. Davies , Kyle R. Covington , Dedee F. Murrell , Julio C. Salas-Alanis , Francis Palisson , Anna L. Bruckner , William Robinson , Cristina Has , Leena Bruckner-Tuderman , Matthias Titeux , Marcel F. Jonkman , Elham Rashidghamat , Su M. Lwin , Jemima E. Mellerio , John A. McGrath , Johann W. Bauer , Alain Hovnanian , Kenneth Y. Tsai , Andrew P. South

Early-onset squamous cell carcinoma in recessive dystrophic epidermolysis bullosa patients is characterized by APOBEC mutagenesis.

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Epithelial HMGB1 Delays Skin Wound Healing and Drives Tumor Initiation by Priming Neutrophils for NET Formation

2019 , Esther Hoste , Christian Maueröder , Lisette van Hove , Leen Catrysse , Hanna-Kaisa Vikkula , Mozes Sze , Bastiaan Maes , Dyah Karjosukarso , Liesbet Martens , Amanda Gonçalves , Eef Parthoens , Ria Roelandt , Wim Declercq , FUENTES BUSTOS, MARIA IGNACIA , Francis Palisson , Sergio Gonzalez , Julio C. Salas-Alanis , Louis Boon , Peter Huebener , Klaas Willem Mulder , Kodi Ravichandran , Yvan Saeys , Robert Felix Schwabe , Geert van Loo

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Longitudinal study of wound healing status and bacterial colonisation of Staphylococcus aureus and Corynebacterium diphtheriae in epidermolysis bullosa patients

2022 , FUENTES BUSTOS, MARIA IGNACIA , YUBERO GONCALVEZ, MARIA JOAO , Pilar Morandé , Carmen Varela , Karen Oróstica , Francisco Acevedo , REBOLLEDO JARAMILLO, BORIS EDUARDO , Esteban Arancibia , PORTE TORRE, LORENA ISABEL , PALISSON ETCHARREN, FRANCIS

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Collagen VII maintains proteostasis in dermal fibroblasts by scaffolding TANGO1 cargo

2022 , Qingqing Cao , Grace Tartaglia , Michael Alexander , Pyung Hung Park , Shiv Poojan , Mehdi Farshchian , FUENTES BUSTOS, MARIA IGNACIA , Mei Chen , John A. McGrath , PALISSON ETCHARREN, FRANCIS , Julio Salas-Alanis , Andrew P. South

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Outcomes and Predictors for Re-stenosis of Esophageal Stricture in Epidermolysis Bullosa: A Multicenter Cohort Study

2020 , Elena Pope , Mark Mansour , Maria Berseneva , Carmen Liy-Wong , Julio Salas , FUENTES BUSTOS, MARIA IGNACIA , YUBERO GONCALVEZ, MARIA JOAO , PALISSON ETCHARREN, FRANCIS , Anna Martinez , Jemima Mellerio , Irene Lara-Corrales , Anes Yang , Dedee Murrell , Mauricio Torres-Pradilla , Anne Lucky

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