Epithelial HMGB1 Delays Skin Wound Healing and Drives Tumor Initiation by Priming Neutrophils for NET Formation

Journal
Cell Reports
ISSN
2211-1247
Date Issued
2019
Author(s)
Esther Hoste
Christian Maueröder
Lisette van Hove
Leen Catrysse
Hanna-Kaisa Vikkula
Mozes Sze
Bastiaan Maes
Dyah Karjosukarso
Liesbet Martens
Amanda Gonçalves
Eef Parthoens
Ria Roelandt
Wim Declercq
Sergio Gonzalez
Julio C. Salas-Alanis
Louis Boon
Peter Huebener
Klaas Willem Mulder
Kodi Ravichandran
Yvan Saeys
Robert Felix Schwabe
Geert van Loo
Type
Resource Types::text::journal::journal article
Scopus ID
2-s2.0-85075512558
WoS ID
WOS:000499377000014
DOI
URL
URL Institutional Repository
Cite this document
Hoste, E., Maueröder, C., Van Hove, L., Catrysse, L., Vikkula, H.-K., Sze, M., Maes, B., Karjosukarso, D., Martens, L., Gonçalves, A., Parthoens, E., Roelandt, R., Declercq, W., Fuentes, I., Palisson, F., Gonzalez, S., Salas-Alanis, J. C., Boon, L., Huebener, P., … Van Loo, G. (2019). Epithelial hmgb1 delays skin wound healing and drives tumor initiation by priming neutrophils for net formation. Cell Reports, 29(9), 2689-2701.e4. https://doi.org/10.1016/j.celrep.2019.10.104
Project(s)
Subjects
group box 1

; 

extracellular trap formation

; 

epidermal-cells

; 

necrosis-factor

; 

stem-cells

; 

mice

; 

expression

; 

receptor

; 

release

; 

netosis

; 

extracellular traps

; 

hmgb1 protein

; 

humans

; 

neutrophils

; 

skin

; 

tumor microenvironment

; 

wound healing

; 

high mobility group b1 protein

; 

protein kinase

; 

protein ripk1

; 

tumor necrosis factor

; 

unclassified drug

; 

high mobility group b1 protein

; 

animal cell

; 

animal experiment

; 

animal model

; 

animal tissue

; 

article

; 

blister

; 

cancer susceptibility

; 

carcinogenicity

; 

controlled study

; 

epidermolysis bullosa dystrophica

; 

extracellular trap

; 

female

; 

human

; 

human cell

; 

keratinocyte

; 

male

; 

molecular mechanics

; 

mouse

; 

nonhuman

; 

priority journal

; 

protein function

; 

protein targeting

; 

regulatory mechanism

; 

skin carcinogenesis

; 

skin epithelium

; 

skin tumor

; 

tumor microenvironment

; 

wound healing impairment

; 

extracellular trap

; 

metabolism

; 

neutrophil

; 

pathology

; 

skin

; 

wound healing