BENAVENTE PEREZ, FRANCISCA

Preferred name

Main Affiliation

Facultad de Medicina Clínica Alemana Universidad del Desarrollo

ORCID

0000-0001-8245-2673

Scopus Author ID

55246387800

Goggle Scholar

https://scholar.google.com/citations?hl=es&user=QUj9Q3AAAAAJ

Now showing 1 - 4 of 4

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Online Intervention Targeting Postnatal Depression and Anxiety in Chilean First-Time Mothers: Feasibility Trial
(2023)
COO CALCAGNI, SOLEDAD
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María Ignacia García
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PÉREZ EWERT, JANET CAROLA
;
Marcia Olhaberry
;
ALDONEY RAMIREZ, DANIELA
<jats:title>Abstract</jats:title> <jats:sec> <jats:title>Objective</jats:title> <jats:p>Internet-based interventions may positively impact maternal symptoms of postnatal depression and anxiety. This study assessed the feasibility, acceptability, perceived usefulness, and preliminary effectiveness of an m-Health version of “What Were We Thinking?” (m-WWWT).</jats:p> </jats:sec> <jats:sec> <jats:title>Methods</jats:title> <jats:p>A mixed-methods with a 2-arm randomized parallel design was used. From a total of 477 women, 157 met the inclusion criteria. 128 first-time mothers of full-term infants, aged 4–10 weeks, who received health care at primary public health centers in Chile, were randomly assigned to the experimental (EG, n = 65) or control (CG, n = 63) groups; data of 104 of them (53 and 51, respectively) was analyzed. We used percentages and rates to measure feasibility outcomes and mixed analysis of variance (ANOVA) and latent class analyses (LCA) to assess preliminary effectiveness. Participants completed questionnaires on mental health, social support, and maternal self-efficacy upon recruitment and 3 months after completing the intervention. For the qualitative component, 12 women from the EG were interviewed.</jats:p> </jats:sec> <jats:sec> <jats:title>Results</jats:title> <jats:p>Quantitative results show good feasibility outcomes, such as high recruitment (82%), low attrition (EG = 12% and CG = 17%), and high follow-up (EG = 97% and CG = 91%) rates. Qualitative results indicate high acceptability and perceived usefulness of m-WWWT. Mixed ANOVA did not show significant differences between the groups (all p &gt;.05). However, multinomial regression analysis in LCA showed that women with low baseline symptoms of depression and anxiety benefit from the intervention (B = 0.43, 95% confidence interval 1.09–2.16).</jats:p> </jats:sec> <jats:sec> <jats:title>Conclusion</jats:title> <jats:p>m-WWWT is feasible to be implemented in Chile; future studies are needed to assess the intervention’s effectiveness.</jats:p> </jats:sec>
Scopus© Citations 5 2
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Bone regeneration based on stem cells derived from bone marrow, iliac crest, or adipose tissue: a scoping review protocol of clinical applications for dental implant site preparation
(Chimera Innova Group, 2025-12-03)
Valentina Veloso-Casado
;
José Tomás Ramos-Rojas
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Francisca Francisca
;
Karla Ogaz-Muñoz
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Camilo Montero-Olivares
<jats:p>Introduction: Dental implant therapy is widely recognized as the gold standard for tooth replacement; however, bone atrophy frequently necessitates augmentation procedures to ensure implant success. Conventional grafting methods, while effective, are limited by factors such as donor site morbidity, immunogenicity, and inconsistent osteogenic potential. Mesenchymal stem cells (MSCs) have emerged as a promising alternative due to their capacity for osteogenic differentiation and immunomodulation. Despite rapid advancements, clinical translation remains hindered by variability in cell source, processing protocols, and outcome measures. This scoping review aims to systematically map current clinical applications of MSC-based bone regeneration using bone marrow, iliac crest, or adipose tissue specifically for dental implant site preparation. Methods: Following the Arksey and O’Malley framework and JBI Manual for Scoping Reviews, this study adheres to PRISMA-ScR guidelines. Eligible studies will include clinical trials and observational studies evaluating stem cell-based augmentation techniques in human patients undergoing maxillary or mandibular bone regeneration for implant placement. A comprehensive literature search across MEDLINE, EBSCO, and CENTRAL will be supplemented by manual reference screening and expert consultation. Two independent reviewers will conduct study selection and data extraction, focusing on patient characteristics, cell source and processing methods, surgical application, outcomes, and safety profiles. Expected results: The results will provide a structured synthesis of current evidence, highlight key methodological trends and gaps, and support clinicians and researchers in navigating the complex landscape of regenerative strategies in implant dentistry.</jats:p>
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Fathers’ Involvement: Mothers’ Perceived Benefits of Promoting Paternal Involvement Through a WhatsApp-Based Preventive Intervention for Postpartum Depression
(University of Toronto Press Inc. (UTPress), 2024-12-04)
Olga Fernández
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ALDONEY RAMIREZ, DANIELA
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Sofia Fernández
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Francisca Pérez
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María Ignacia García
<jats:sec><jats:title>Introduction:</jats:title><jats:p> Despite the social and cultural changes of the recent decades, the tasks associated with childcare continue to be assumed mainly by women, increasing stress and, in some cases, negatively affecting maternal mental health. The “m-What were we thinking” (m-WWWT) intervention seeks to reduce the risk of developing postpartum depression and anxiety symptoms in women by increasing self-efficacy in caring for a newborn and perceived social support, with a special focus on the partner's role. The objective of this study was to describe the mothers’ perception of how this intervention facilitated the father's parenting involvement. </jats:p></jats:sec><jats:sec><jats:title>Methods:</jats:title><jats:p> Sixty-four text messages from 25 first-time mothers participating in the m-WWWT program were analyzed using the Grounded Theory open and axial coding criteria. </jats:p></jats:sec><jats:sec><jats:title>Results:</jats:title><jats:p> There are four subjective themes linked to fathers and parenthood. The first refers to the loss of the previous balance and increased stress with the arrival of the first child; the second, to the importance of watching the intervention videos together; the third, to the possibility of communicating regarding what is happening; and the fourth, to the shared conceptualization of parenting among the couples. </jats:p></jats:sec><jats:sec><jats:title>Conclusion:</jats:title><jats:p> These findings suggest that m-WWWT positively influences paternal involvement in the postpartum period, which is a relevant factor to promote maternal and infant well-being. </jats:p></jats:sec>
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Novel C1q receptor-mediated signaling controls neural stem cell behavior and neurorepair
(2020)
BENAVENTE PEREZ, FRANCISCA
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Katja M Piltti
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Mitra J Hooshmand
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Aileen A Nava
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Anita Lakatos
<jats:p>C1q plays a key role as a recognition molecule in the immune system, driving autocatalytic complement cascade activation and acting as an opsonin. We have previously reported a non-immune role of complement C1q modulating the migration and fate of human neural stem cells (hNSC); however, the mechanism underlying these effects has not yet been identified. Here, we show for the first time that C1q acts as a functional hNSC ligand, inducing intracellular signaling to control cell behavior. Using an unbiased screening strategy, we identified five transmembrane C1q signaling/receptor candidates in hNSC (CD44, GPR62, BAI1, c-MET, and ADCY5). We further investigated the interaction between C1q and CD44 , demonstrating that CD44 mediates C1q induced hNSC signaling and chemotaxis in vitro, and hNSC migration and functional repair in vivo after spinal cord injury. These results reveal a receptor-mediated mechanism for C1q modulation of NSC behavior and show that modification of C1q receptor expression can expand the therapeutic window for hNSC transplantation.</jats:p>
1Scopus© Citations 28

BENAVENTE PEREZ, FRANCISCA

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