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CARVAJAL BENAVIDES, CÉSAR CRISTÓBAL
Preferred name
CARVAJAL BENAVIDES, CÉSAR CRISTÓBAL
Main Affiliation
Email
CRISTOBALCARVAJAL@UDD.CL
ORCID
0000-0002-1712-7396
Scopus Author ID
53163308500
18 results
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Item type:Product, Dataset - Post-COVID-19 condition: a sex-based analysis of clinical and laboratory trends(2024); ; ; RIVIOTTA, AMY LISA3 - Some of the metrics are blocked by yourconsent settings
Item type:Publication, Therapeutic variability in infants admitted to Latin-American pediatric intensive units due to acute bronchiolitis(2020); Alejandro Donoso<jats:p>Objetivo: describir las terapias utilizadas en lactantes con bronquiolitis aguda admitidos en 20 Unidades de Cuidados Intensivos (UCI) pediátricos miembros de LARed en 5 países latinoamericanos.Pacientes y Método: Estudio observacional retrospectivo, multicéntrico, de datos del Registro Latinoamericano de Falla Respiratoria Aguda Pediátrica. Se incluyeron niños menores de 2 años ingresados a UCI pediátrica por bronquiolitis aguda comunitaria entre mayo-septiembre 2017. Se recolectaron datos demográficos, clínicos, soporte respiratorio, terapias utilizadas y resultados clínicos. Se realizó análisis de subgrupos según ubicación geográfica, tipo financiación y presencia de academia.Resultados: Ingresaron al registro 1.155 pacientes con falla respiratoria aguda. Seis casos fueron excluidos por no tener formulario completo. De los 1.147 pacientes, 908 eran menores de 2 años. De ellos, 467 tuvieron diagnóstico de bronquiolitis aguda, correspondiendo a la principal causa de ingreso a UCI pediátrica por falla respiratoria aguda (51,4%). Las características demográficas y de gravedad entre los centros fueron similares. El soporte máximo respiratorio más frecuente fue cánula nasal de alto flujo (47%), seguido por ventilación mecánica no invasiva (26%) y ventilación mecánica invasiva (17%), con un coeficiente de variación (CV) amplio entre los centros. Hubo una gran dispersión en uso de terapias, siendo frecuente el uso de broncodilatadores, antibióticos y corticoides, con CV hasta 400%. El análisis de subgrupos mostró diferencias significativas en soporte respiratorio y tratamientos utilizados. Un paciente falleció en esta cohorte.Conclusión: Detectamos gran variabilidad en el soporte respiratorio y tratamientos entre UCI pediátricas latinoamericanas. Esta variabilidad no es explicada por disparidades demográficas ni clínicas. Esta heterogeneidad de tratamientos debería promover iniciativas colaborativas para disminuir la brecha entre la evidencia científica y la práctica asistencial.</jats:p>3Scopus© Citations 11 - Some of the metrics are blocked by yourconsent settings
Item type:Publication, Ultra‐Processed Foods and Markers of Systemic Inflammation in Children(Wiley, 2025-09); ; 7 - Some of the metrics are blocked by yourconsent settings
Item type:Publication, Post-COVID-19 condition: a sex-based analysis of clinical and laboratory trends(2024); ; ; Gonzalo Martínez<jats:sec><jats:title>Background and aim</jats:title><jats:p>Post-COVID-19 condition (PCC) encompasses long-lasting symptoms in individuals with COVID-19 and is estimated to affect between 31–67% of patients, with women being more commonly affected. No definitive biomarkers have emerged in the acute stage that can help predict the onset of PCC, therefore we aimed at describing sex-disaggregated data of PCC patients from a local cohort and explore potential acute predictors of PCC and neurologic PCC.</jats:p></jats:sec><jats:sec><jats:title>Methods</jats:title><jats:p>A local cohort of consecutive patients admitted with COVID-19 diagnosis between June 2020 and July 2021 were registered, and clinical and laboratory data were recorded. Only those &lt;65 years, discharged alive and followed up at 6 and 12 months after admission were considered in these analyses. Multivariable logistic regression analysis was performed to explore variables associated with PCC (STATA v 18.0).</jats:p></jats:sec><jats:sec><jats:title>Results</jats:title><jats:p>From 130 patients in the cohort, 104 were contacted: 30% were women, median age of 42 years. At 6 months, 71 (68%) reported PCC symptoms. Women exhibited a higher prevalence of any PCC symptom (87 vs. 60%, <jats:italic>p</jats:italic> = 0.007), lower ferritin (<jats:italic>p</jats:italic> = 0.001) and procalcitonin (<jats:italic>p</jats:italic> = 0.021) and higher TNF levels (<jats:italic>p</jats:italic> = 0.042) in the acute phase compared to men. Being women was independently associated to 7.60 (95% CI 1.27–45.18, <jats:italic>p</jats:italic> = 0.026) higher risk for PCC. Moreover, women had lower return to normal activities 6 and 12 months.</jats:p></jats:sec><jats:sec><jats:title>Conclusion</jats:title><jats:p>Our findings highlight the lasting impact of COVID-19, particularly in young women, emphasising the need for tailored post-COVID care. The lower ferritin levels in women are an intriguing observation, warranting further research. The study argues for comprehensive strategies that address sex-specific challenges in recovery from COVID-19.</jats:p></jats:sec>9Scopus© Citations 3 - Some of the metrics are blocked by yourconsent settings
Item type:Publication, Consecuencias hemodinámicas y respiratorias del síndrome compartimental abdominal en un modelo experimental(2012); 3Scopus© Citations 4 - Some of the metrics are blocked by yourconsent settings
Item type:Publication, Fragilidad: en busca de herramientas de evaluación preoperatoria(2020)Scopus© Citations 2 1 - Some of the metrics are blocked by yourconsent settings
Item type:Publication, Mild hypothermia attenuates lung edema and plasma interleukin-1β in a rat mechanical ventilation-induced lung injury model(2011); 33Scopus© Citations 9 - Some of the metrics are blocked by yourconsent settings
Item type:Publication, Decreased lung compliance increases preload dynamic tests in a pediatric acute lung injury model(2015)Scopus© Citations 1 1 - Some of the metrics are blocked by yourconsent settings
Item type:Publication, Angiotensin-converting enzyme insertion/deletion polymorphism is associated with severe hypoxemia in pediatric ARDS(2011)Scopus© Citations 26 1 - Some of the metrics are blocked by yourconsent settings
Item type:Publication, Mild hypothermia increases pulmonary anti-inflammatory response during protective mechanical ventilation in a piglet model of acute lung injury(2013); Tatiana Salomón15Scopus© Citations 17