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Item type:Publication, Evidence-based clinical standard for the diagnosis and treatment of invasive lung aspergillosis in the patient with oncohematologic disease(Elsevier BV, 2025-03) ;Jorge Alberto Cortés ;Diego Andrés Rodríguez-Lugo ;Martha Carolina Valderrama-Rios ;Ricardo RabagliatiDomenico Capone2 - Some of the metrics are blocked by yourconsent settings
Item type:Publication, Impact of Evidence‐Based Stroke Care on Patient Outcomes: A Multilevel Analysis of an International Study(2019); ;Xian Li ;Sandy Middleton ;Caroline Watkins<jats:sec xml:lang="en"> <jats:title>Background</jats:title> <jats:p xml:lang="en"> The uptake of proven stroke treatments varies widely. We aimed to determine the association of evidence‐based processes of care for acute ischemic stroke ( <jats:styled-content style="fixed-case">AIS</jats:styled-content> ) and clinical outcome of patients who participated in the HEADPOST (Head Positioning in Acute Stroke Trial), a multicenter cluster crossover trial of lying flat versus sitting up, head positioning in acute stroke. </jats:p> </jats:sec> <jats:sec xml:lang="en"> <jats:title>Methods and Results</jats:title> <jats:p xml:lang="en"> Use of 8 <jats:styled-content style="fixed-case">AIS</jats:styled-content> processes of care were considered: reperfusion therapy in eligible patients; acute stroke unit care; antihypertensive, antiplatelet, statin, and anticoagulation for atrial fibrillation; dysphagia assessment; and physiotherapist review. Hierarchical, mixed, logistic regression models were performed to determine associations with good outcome (modified Rankin Scale scores 0–2) at 90 days, adjusted for patient and hospital variables. Among 9485 patients with AIS, implementation of all processes of care in eligible patients, or “defect‐free” care, was associated with improved outcome (odds ratio, 1.40; 95% CI, 1.18–1.65) and better survival (odds ratio, 2.23; 95% <jats:styled-content style="fixed-case">CI</jats:styled-content> , 1.62–3.09). Defect‐free stroke care was also significantly associated with excellent outcome (modified Rankin Scale score 0–1) (odds ratio, 1.22; 95% <jats:styled-content style="fixed-case">CI</jats:styled-content> , 1.04–1.43). No hospital characteristic was independently predictive of outcome. Only 1445 (15%) of eligible patients with AIS received all processes of care, with significant regional variations in overall and individual rates. </jats:p> </jats:sec> <jats:sec xml:lang="en"> <jats:title>Conclusions</jats:title> <jats:p xml:lang="en"> Use of evidence‐based care is associated with improved clinical outcome in <jats:styled-content style="fixed-case">AIS</jats:styled-content> . Strategies are required to address regional variation in the use of proven <jats:styled-content style="fixed-case">AIS</jats:styled-content> treatments. </jats:p> </jats:sec> <jats:sec xml:lang="en"> <jats:title>Clinical Trial Registration</jats:title> <jats:p xml:lang="en"> <jats:styled-content style="fixed-case">URL</jats:styled-content> : <jats:ext-link xmlns:xlink="http://www.w3.org/1999/xlink" ext-link-type="uri" xlink:href="https://www.clinicaltrials.gov">https://www.clinicaltrials.gov</jats:ext-link> . Unique Identifier: <jats:styled-content style="fixed-case">NCT</jats:styled-content> 02162017. </jats:p> </jats:sec>1 8Scopus© Citations 21 - Some of the metrics are blocked by yourconsent settings
Item type:Publication, Protecting children from iatrogenic harm during
<scp>COVID19</scp>
pandemic(2020) ;Anna Camporesi ;Franco Díaz‐Rubio ;Christopher L CarrollSebastián González‐Dambrauskas9Scopus© Citations 5 - Some of the metrics are blocked by yourconsent settings
Item type:Publication, 1 - Some of the metrics are blocked by yourconsent settings
Item type:Publication, Settings and monitoring of mechanical ventilation during physical therapy in adult critically ill patients: protocol for a scoping review(2019); ; ;Anita Jasmén Sepúlveda; Jorge Molina Blamey<jats:sec><jats:title>Introduction</jats:title><jats:p>Early mobilisation has been extensively advocated to improve functional outcomes in critically ill patients, even though consistent evidence of its benefits has remained elusive. These conflicting results could be explained by a lack of knowledge on the optimal dosage of physical therapy and a mismatch between ventilatory support and exercise-induced patient ventilatory demand. Modern mechanical ventilators provide real-time monitoring of respiratory/metabolic variables and ventilatory setting that could be used for physical therapy dosage or ventilatory support titration, allowing individualised interventions in these patients. The aim of this review is to comprehensively map and summarise current knowledge on adjustments of respiratory support and respiratory or metabolic monitoring during physical therapy in adult critically ill mechanically ventilated patients.</jats:p></jats:sec><jats:sec><jats:title>Methods and analysis</jats:title><jats:p>This is a scoping review protocol based on the methodology of the Joanna-Briggs-Institute. The search strategy will be conducted from inception to 30 June 2019 as a cut-off date in PubMed, CINAHL, Rehabilitation & Sport Medicine, Scielo Citation Index, Epistemónikos, Clinical Trials, PEDro and Cochrane Library, performed by a biomedical librarian and two critical care physiotherapists. All types of articles will be selected, including conference abstracts, clinical practice guidelines and expert recommendations. Bibliometric variables, patient characteristics, physical therapy interventions, ventilator settings and respiratory or metabolic monitoring will be extracted. The identified literature will be analysed by four critical care physiotherapists and reviewed by a senior critical care physician.</jats:p></jats:sec><jats:sec><jats:title>Ethics and dissemination</jats:title><jats:p>Ethical approval is not required. The knowledge-translation of the results will be carried out based on the End-of-Grant strategies: diffusion, dissemination and application. The results will be published in a peer-review journal, presentations will be disseminated in relevant congresses, and recommendations based on the results will be developed through training for mechanical ventilation and physical therapy stakeholders.</jats:p></jats:sec>5 1Scopus© Citations 5 - Some of the metrics are blocked by yourconsent settings
Item type:Publication, Should evidence or sound clinical reasoning dictate patient care?(2016) ;Phillip S. Sizer ;MAURI STECCA, MANUEL VICENTE ;Kenneth Learman ;Clare JonesNorman ‘Skip’ Gill17Scopus© Citations 10 - Some of the metrics are blocked by yourconsent settings
Item type:Publication, Chilean consensus of prevention, diagnosis and treatment of Clostridium difficile-associated diarrhea(2016) ;Cristian Hernández-Rocha ;Paola Pidal ;M. Cristina Ajenjo ;Rodrigo QueraMarcela QuintanillaScopus© Citations 12 26 - Some of the metrics are blocked by yourconsent settings
Item type:Publication, Developing clinical practice guidelines for epilepsy: A report from the ILAE Epilepsy Guidelines Working Group(2015) ;Khara M. Sauro ;Samuel Wiebe ;Emilio Perucca ;Jacqueline FrenchColin Dunkley16Scopus© Citations 36 - Some of the metrics are blocked by yourconsent settings
Item type:Publication, Management of nonalcoholic fatty liver disease: An evidence-based clinical practice review(2014) ;Juan P ArabRODRIGO ZAPATA LARRAIN2Scopus© Citations 54 - Some of the metrics are blocked by yourconsent settings
Item type:Publication, Therapeutic alternatives for the treatment of type 1 hepatorenal syndrome: A Delphi technique-based consensus(2016) ;Juan P Arab ;Juan C Claro ;Juan P Arancibia ;JORGE SEBASTIAN CONTRERAS ROMOFernando GómezScopus© Citations 8 2