ESBL-Producing Escherichia coli Carrying CTX-M Genes Circulating among Livestock, Dogs, and Wild Mammals in Small-Scale Farms of Central Chile
Journal
Antibiotics
ISSN
2079-6382
Date Issued
2021
Author(s)
Julio A. Benavides
Marília Salgado-Caxito
Andrés Opazo-Capurro
Paulina González Muñoz
Ana Piñeiro
Macarena Otto Medina
Javier Millán
Type
Resource Types::text::journal::journal article
URL Institutional Repository
Abstract
Antibiotic-resistant bacteria of critical importance for global health such as extended-spectrum beta-lactamases-producing (ESBL)-Escherichia coli have been detected in livestock, dogs, and wildlife worldwide. However, the dynamics of ESBL-E. coli between these animals remains poorly understood, particularly in small-scale farms of low and middle-income countries where contact between species can be frequent. We compared the prevalence of fecal carriage of ESBL-E. coli among 332 livestock (207 cows, 15 pigs, 60 horses, 40 sheep, 6 goats, 4 chickens), 82 dogs, and wildlife including 131 European rabbits, 30 rodents, and 12 Andean foxes sharing territory in peri-urban localities of central Chile. The prevalence was lower in livestock (3.0%) and wildlife (0.5%) compared to dogs (24%). Among 47 ESBL-E. coli isolates recovered, CTX-M-group 1 was the main ESBL genotype identified, followed by CTX-M-groups 2, 9, 8, and 25. ERIC-PCR showed no cluster of E. coli clones by either host species nor locality. To our knowledge, this is the first report of ESBL-E. coli among sheep, cattle, dogs, and rodents of Chile, confirming their fecal carriage among domestic and wild animals in small-scale farms. The high prevalence of ESBL-E. coli in dogs encourages further investigation on their role as potential reservoirs of this bacteria in agricultural settings.
Cite this document
Benavides, J. A., Salgado-Caxito, M., Opazo-Capurro, A., González Muñoz, P., Piñeiro, A., Otto Medina, M., Rivas, L., Munita, J., & Millán, J. (2021). Esbl-producing escherichia coli carrying ctx-m genes circulating among livestock, dogs, and wild mammals in small-scale farms of central chile. Antibiotics, 10(5), 510. https://doi.org/10.3390/antibiotics10050510