<jats:p>
The recent development of new antimicrobials active against carbapenemase-producing
<jats:italic>Enterobacteriales</jats:italic>
(CPE) has brought new hope for the treatment of infections due to these organisms. However, the evolving epidemiology of bacteria with carbapenemases may complicate management, as providers are faced with treating patients colonized by bacteria producing multiple carbapenemases.
</jats:p>