Managing All the Genotypic Knowledge: Approach to a Septic Patient Colonized by Different Enterobacteriales with Unique Carbapenemases

Journal
Antimicrobial Agents and Chemotherapy
ISSN
0066-4804
1098-6596
Date Issued
2019
Author(s)
Stacy C. Park
Alexander M. Wailan
Katie E. Barry
Kasi Vegesana
Joanne Carroll
Amy J. Mathers
William R. Miller
Type
Resource Types::text::journal::journal article
Scopus ID
2-s2.0-85070618750
WoS ID
WOS:000477070900002
DOI
URL
URL Institutional Repository
Abstract
<jats:p>
The recent development of new antimicrobials active against carbapenemase-producing
<jats:italic>Enterobacteriales</jats:italic>
(CPE) has brought new hope for the treatment of infections due to these organisms. However, the evolving epidemiology of bacteria with carbapenemases may complicate management, as providers are faced with treating patients colonized by bacteria producing multiple carbapenemases.
</jats:p>
Cite this document
Park, S. C., Wailan, A. M., Barry, K. E., Vegesana, K., Carroll, J., Mathers, A. J., Miller, W. R., & Munita, J. M. (2019). Managing all the genotypic knowledge: Approach to a septic patient colonized by different enterobacteriales with unique carbapenemases. Antimicrobial Agents and Chemotherapy, 63(8), e00029-19. https://doi.org/10.1128/AAC.00029-19
Project(s)
Subjects
oxa-48

; 

raoultella planticola

; 

carbapenem-resistant enterobacteriales (cre)

; 

carbapenemase-producing enterobacteriales (cpe)

; 

ceftazidime-avibactam

; 

adult

; 

anti-bacterial agents

; 

bacteremia

; 

bacterial proteins

; 

beta-lactamases

; 

enterobacteriaceae

; 

enterobacteriaceae infections

; 

escherichia coli

; 

fibrosis

; 

humans

; 

klebsiella oxytoca

; 

male

; 

avibactam plus ceftazidime

; 

carbapenemase

; 

ceftolozane

; 

colistin

; 

meropenem

; 

metronidazole

; 

micafungin

; 

piperacillin plus tazobactam

; 

vancomycin

; 

antiinfective agent

; 

bacterial protein

; 

beta lactamase

; 

carbapenemase

; 

adult

; 

anemia

; 

antibiotic sensitivity

; 

article

; 

bacteremia

; 

bacterial colonization

; 

blood culture

; 

blood flow velocity

; 

carbapenem-resistant enterobacteriaceae

; 

case report

; 

cholelithiasis

; 

clinical article

; 

comfort measures only order

; 

computer assisted tomography

; 

continuous renal replacement therapy

; 

decompensated liver cirrhosis

; 

disease course

; 

enterobacteriaceae infection

; 

escherichia coli

; 

fever

; 

genotype

; 

hemodialysis

; 

hemoperitoneum

; 

hemorrhagic shock

; 

hospital admission

; 

hospital readmission

; 

human

; 

hypotension

; 

klebsiella oxytoca

; 

leukocyte count

; 

male

; 

medical intensive care unit

; 

nonhuman

; 

pantoea

; 

paracentesis

; 

patient care

; 

priority journal

; 

raoultella planticola

; 

refractory anemia

; 

respiratory failure

; 

tachycardia

; 

tachypnea

; 

bacteremia

; 

complication

; 

enterobacteriaceae

; 

enterobacteriaceae infection

; 

fibrosis

; 

genetics

; 

isolation and purification

; 

microbiology

; 

pathogenicity