UNDURRAGA FOURCADE, JUAN PABLO

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Dataset - Country-level gender inequality is associated with structural differences in the brains of women and men
(OSF, 2023)
BILLEKE BOBADILLA, PABLO ERNESTO
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UNDURRAGA FOURCADE, JUAN PABLO
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Dataset - Intra and inter-individual variability in functional connectomes of patients with First Episode of Psychosis
(ZENODO, 2023)
UNDURRAGA FOURCADE, JUAN PABLO
1
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Correction: Obesity and brain structure in schizophrenia – ENIGMA study in 3021 individuals
(2023)
Sean R. McWhinney
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Katharina Brosch
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Vince D. Calhoun
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Benedicto Crespo-Facorro
;
Nicolas A. Crossley
1Scopus© Citations 1
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The Implementation of Psychological Interventions in First Episode of Psychosis Services in Chile
(2018)
UNDURRAGA FOURCADE, JUAN PABLO
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Castaneda, CP
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Mena, C; Gonzalez
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A; Nachar
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R; Monje, M
4
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Psychoeducation in bipolar disorder with a SIMPLe smartphone application: Feasibility, acceptability and satisfaction
(2016)
Diego Hidalgo-Mazzei
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Ainoa Mateu
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María Reinares
;
Andrea Murru
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Caterina del Mar Bonnín
16Scopus© Citations 101
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Brain Network Architecture Intricately Linked to Morphological Abnormalities in Major Psychiatric Disorders
(2021)
Foivos Georgiadis
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Lariviere, Sara
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Vaughan Carr
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Stanley Catts
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Green, Melissa
1
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Functional Dysconnectivity in Ventral Striatocortical Systems in 22q11.2 Deletion Syndrome
(2021)
Ángeles Tepper
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Analía Cuiza
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Luz María Alliende
;
Carlos Mena
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Juan Pablo Ramirez-Mahaluf
<jats:title>Abstract</jats:title> <jats:p>22q11.2 deletion syndrome (22q11.2DS) is a genetic neurodevelopmental disorder that represents one of the greatest known risk factors for psychosis. Previous studies in psychotic subjects without the deletion have identified a dopaminergic dysfunction in striatal regions, and dysconnectivity of striatocortical systems, as an important mechanism in the emergence of psychosis. Here, we used resting-state functional MRI to examine striatocortical functional connectivity in 22q11.2DS patients. We used a 2 × 2 factorial design including 125 subjects (55 healthy controls, 28 22q11.2DS patients without a history of psychosis, 10 22q11.2DS patients with a history of psychosis, and 32 subjects with a history of psychosis without the deletion), allowing us to identify network effects related to the deletion and to the presence of psychosis. In line with previous results from psychotic patients without 22q11.2DS, we found that there was a dorsal to ventral gradient of hypo- to hyperstriatocortical connectivity related to psychosis across both patient groups. The 22q11.2DS was additionally associated with abnormal functional connectivity in ventral striatocortical networks, with no significant differences identified in the dorsal system. Abnormalities in the ventral striatocortical system observed in these individuals with high genetic risk to psychosis may thus reflect a marker of illness risk.</jats:p>
1Scopus© Citations 6
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The enduring gap in educational attainment in schizophrenia according to the past 50 years of published research: a systematic review and meta-analysis
(2022)
Barbara Iruretagoyena
;
UNDURRAGA FOURCADE, JUAN PABLO
14
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Safety, tolerability, and risks associated with first- and second-generation antipsychotics: a state-of-the-art clinical review
(2017)
Marco Solmi
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Andrea Murru
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Isabella Pacchiarotti
;
Juan Undurraga
;
Nicola Veronese
4Scopus© Citations 400
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Country-level gender inequality is associated with structural differences in the brains of women and men
(2023)
André Zugman
;
Luz María Alliende
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Vicente Medel
;
Richard A.I. Bethlehem
;
Jakob Seidlitz
<jats:p>Gender inequality across the world has been associated with a higher risk to mental health problems and lower academic achievement in women compared to men. We also know that the brain is shaped by nurturing and adverse socio-environmental experiences. Therefore, unequal exposure to harsher conditions for women compared to men in gender-unequal countries might be reflected in differences in their brain structure, and this could be the neural mechanism partly explaining women’s worse outcomes in gender-unequal countries. We examined this through a random-effects meta-analysis on cortical thickness and surface area differences between adult healthy men and women, including a meta-regression in which country-level gender inequality acted as an explanatory variable for the observed differences. A total of 139 samples from 29 different countries, totaling 7,876 MRI scans, were included. Thickness of the right hemisphere, and particularly the right caudal anterior cingulate, right medial orbitofrontal, and left lateral occipital cortex, presented no differences or even thicker regional cortices in women compared to men in gender-equal countries, reversing to thinner cortices in countries with greater gender inequality. These results point to the potentially hazardous effect of gender inequality on women’s brains and provide initial evidence for neuroscience-informed policies for gender equality.</jats:p>
Scopus© Citations 38 5

UNDURRAGA FOURCADE, JUAN PABLO

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