BRUNSER RABOVICH, ALEJANDRO MICHEL
Thumbnail Image
Preferred name
BRUNSER RABOVICH, ALEJANDRO MICHEL
Main Affiliation
Email
abrunser@alemana.cl
ORCID
Scopus Author ID
26644722200

Research Output

2024 2024 2023 2023 2022 2022 2021 2021 2020 2020 2019 2019 2018 2018 2017 2017 2016 2016 2015 2015 0 0 2 2 4 4 6 6 8 8 10 10 12 12 14 14 16 16
Now showing 1 - 10 of 68
No Thumbnail Available
Publication

Seasonal trend of cervical artery dissection in a Chilean cohort

2019 , RECULE GONZALEZ, FRANCISCA , MAZZON AGURTO, ENRICO , DIAZ TAPIA, VIOLETA DEL CARMEN , Rocha, Diego , BRUNSER RABOVICH, ALEJANDRO MICHEL , De La Barra, Camila , Zuniga, Paulo , Dominga Garcia, Maria , Gabriel Cavada , MUÑOZ VENTURELLI, PAULA ANDREA , Zeballos, Shirley , Charaf, Yusef

View
No Thumbnail Available
Publication

The Role of TCD in the Evaluation of Acute Stroke

2016 , BRUNSER, ALEJANDRO , Eloy Mansilla , Arnold Hoppe , Verónica Olavarría , Emi Sujima , Pablo M. Lavados

View
No Thumbnail Available
Publication

Cervical Artery Dissection in Postpartum Women after Cesarean and Vaginal Delivery

2022 , Francisca Urrutia , MAZZON AGURTO, ENRICO , BRUNSER, ALEJANDRO , DIAZ TAPIA, VIOLETA DEL CARMEN , CALDERON GIADROSIC, JUAN FRANCISCO , STECHER GUZMAN, XIMENA PATRICIA , Tomas Bernstein , Paulo Zuñiga , SCHILLING REDLICH, ANDREA INGRID , MUÑOZ VENTURELLI, PAULA

View
No Thumbnail Available
Publication

Pre-stroke adherence to a Mediterranean diet pattern is associated with lower acute ischemic stroke severity: a cross-sectional analysis of a prospective hospital-register study

2020 , Pablo M. Lavados , MAZZON AGURTO, ENRICO , Alexis Rojo , BRUNSER, ALEJANDRO , Verónica V. Olavarría

Abstract Background High adherence to a Mediterranean Diet is associated with reduced incidence and mortality of acute ischemic stroke (AIS) but may also be associated with severity. Our purpose was to investigate the association of adherence to a Mediterranean diet and severity in a prospective hospital register of AIS patients. Methods We included AIS patients admitted from February 2017 to July 2019. All were assessed by a neurologist with a standard stroke protocol, including NIHSS. Adherence to Mediterranean diet was prospectively measured by the 14-point Mediterranean Diet Adherence Screener (MEDAS) and defined as low (0–6 points) or high (7–14 points). Demographic and clinical characteristics were compared by group with univariate analysis. A Generalized Linear Model (GLM) was used to investigate the association of admission NIHSS as a continuous ordinal variable and an ordinal logistic regression (OLR) analysis to determine the independent association of the NIHSS quartiles with adherence to Mediterranean diet. Results Three hundred sixty-eight patients were included, mean age 68.3 (17.7), 158 (42.9%) females. The median NIHSS score was 3 (IQR 1–9) and the median MEDAS score was 6 (IQR 4.5–8). Patients with high MEDAS scores had significantly lower; admission NIHSS scores, sedentary lifestyle, body mass index, total and LDL cholesterol levels, but higher alcohol consumption. After adjustments, high adherence to Mediterranean diet remained independently associated with lower stroke severity both in the GLM (β coefficient = − 0.19, p = 0.01) and in the OLR model (OR for lower NIHSS quartiles 0.6 (95% CI 0.37–0.98, p = 0.04). Conclusions Higher pre-stroke adherence to a Mediterranean diet is independently associated with lower AIS severity.

View
No Thumbnail Available
Publication

Validity of the NIHSS in predicting arterial occlusion in cerebral infarction is time-dependent

2010 , V. V. Olavarria , DELGADO BECERRA, OROZIMBA IRIS , HOPPE WIEGERING, ARNOLD JOHANNES GOTTLIEB , BRUNSER, ALEJANDRO , D. Carcamo , DIAZ TAPIA, VIOLETA DEL CARMEN , LAVADOS GERMAIN, PABLO MANUEL

View
No Thumbnail Available
Publication

IMPACT OF ETHNICITY ON ARTERIAL RECANALIZATION IN ACUTE ISCHEMIC STROKE

2020 , BRUNSER RABOVICH, ALEJANDRO MICHEL , Sharma, A. , Saqqur, M. , Tsivgoulis, G. , Eggers, J. , Mikulik, R. , Katsanos, A. H. , Vadikolias, K. , Rubiera, M. , Shahripour, R. , Thang-Nguyen, H. , Martinez-Sanchez, P. , Hatzitolios, A. , Shuaib, A. , Derksen, C. , Voumvourakis, K. , Psaltopoulou, T. , Alexandrov, A. W. , Alexandrov, A. , Sharma, V.

View
No Thumbnail Available
Publication

EFFECT OF AGE ON ARTERIAL RECANALIZATION AND OUTCOME IN THROMBOLYSED ACUTE ISCHEMIC STROKE PATIENTS

2020 , BRUNSER RABOVICH, ALEJANDRO MICHEL , Sharma, A. , Tsivgoulis, G. , Eggers, J. , Mikulik, R. , Katsanos, A. H. , Vadikolias, K. , Rubiera, M. , Shahripour, R. , Thang-Nguyen, H. , Martinez-Sanchez, P. , Hatzitolios, A. , Shuaib, A. , Voumvourakis, K. , Derksen, C. , Psaltopoulou, T. , Alexandrov, A. W. , Alexandrov, A. , Saqqur, M

View
No Thumbnail Available
Publication

Association between spontaneous internal carotid artery dissection and perivascular adipose tissue attenuation on computed tomography angiography

2023 , Kevin Cheng , Andrew Lin , STECHER GUZMAN, XIMENA PATRICIA , Tomas Bernstein , Paulo Zuñiga , Gonzalo Martinez , BRUNSER, ALEJANDRO , DIAZ TAPIA, VIOLETA DEL CARMEN , MAZZON AGURTO, ENRICO , William Cameron , Stephen J Nicholls , Sanjay Patel , Damini Dey , Dennis TL Wong , MUÑOZ VENTURELLI, PAULA ANDREA

Background: Spontaneous cervical artery dissection (sCAD) is a leading cause of ischemic stroke in young patients. Studies using high-resolution magnetic resonance imaging and positron emission tomography have suggested vessel wall inflammation to be a pathogenic factor in sCAD. Computed tomography (CT) attenuation of perivascular adipose tissue (PVAT) is an established non-invasive imaging biomarker of inflammation in coronary arteries, with higher attenuation values reflecting a greater degree of vascular inflammation. Objectives: We evaluate the CT attenuation of PVAT surrounding the internal carotid artery (PVATcarotid) with and without spontaneous dissection. Methods: Single-center prospective observational study of 56 consecutive patients with CT-verified spontaneous dissection of the internal carotid artery (ICA). Of these patients, six underwent follow-up computed tomography angiography (CTA). Twenty-two patients who underwent CTA for acute neurological symptoms but did not have dissection formed the control group. Using semi-automated research software, PVATcarotid was measured as the mean Hounsfield unit (HU) attenuation of adipose tissue within a defined volume of interest surrounding the ICA. Results: PVATcarotid was significantly higher around dissected ICA compared with non-dissected contralateral ICA in the same patients (−58.7 ± 10.2 vs −68.9 ± 8.1 HU, p < 0.0001) and ICA of patients without dissection (−58.7 ± 10.2 vs −69.3 ± 9.3 HU, p < 0.0001). After a median follow-up of 89 days, there was a significant reduction in PVATcarotid around dissected ICA (−57.5 ± 13.4 to −74.3 ± 10.5 HU, p < 0.05), while no change was observed around non-dissected contralateral ICA (−71.0 ± 4.4 to −74.1 ± 4.1 HU, p = 0.19). ICA dissection was an independent predictor of PVATcarotid following multivariable adjustment for age and the presence of ICA occlusion. Conclusion: PVATcarotid is elevated in the presence of sCAD and may decrease following the acute event.

View
No Thumbnail Available
Publication

Risk Factors and Diet Components Determining Adherence to the Mediterranean Diet in Acute Ischemic Stroke Patients: A Cross-Sectional Analysis of a Prospective Hospital Register Study

2022 , OLAVARRIA IANISZEWSKY, VERONICA VIVIANA , NAVIA GONZALEZ, VICTOR HUGO , MAZZON AGURTO, ENRICO , Alexis Rojo , BRUNSER, ALEJANDRO , LAVADOS GERMAIN, PABLO MANUEL

View
No Thumbnail Available
Publication

In-Hospital Acute Ischemic Stroke is Associated with Worse Outcome: Experience of a Single Center in Santiago Chile

2021 , BRUNSER RABOVICH, ALEJANDRO MICHEL , Patricia Araneda , NAVIA GONZALEZ, VICTOR HUGO , MAZZON AGURTO, ENRICO , Gabriel Cavada , MUÑOZ VENTURELLI, PAULA ANDREA , OLAVARRIA IANISZEWSKY, VERONICA VIVIANA , LAVADOS GERMAIN, PABLO MANUEL

View