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Latin American association for the study of the liver (ALEH) guidance on postoperative care after liver transplantation
(Elsevier BV, 2025-07)
Liana Codes
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ZAPATA LARRAIN, RODRIGO
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Manuel Mendizabal
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Alfeu de Medeiros Fleck Junior
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Juan Carlos Restrepo
7Scopus© Citations 1
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Exploring contextual factors for management and prevention of running-related injuries: runners and experts’ perspectives
(BMJ, 2025-04)
BESOMI MOLINA, MANUELA
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Roa-alcaino Sonia
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Ángela Lombardi
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Rocío Vélez-Rivera
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LEPPE ZAMORA, JAIME ESTEBAN
Running is one of the most accessible and popular physical activities worldwide; however, injuries are the main barrier to sustaining running practice. While quantitative studies have explored prevalence and risk factors, a critical gap exists in understanding subjective experiences, perceptions and contextual influences on injury management and prevention. This qualitative study aimed to explore the perspectives of runners and experts regarding injury perception, management and prevention, as well as the contextual influence of these processes. Using a secondary data analysis approach, this study drew from qualitative semistructured interviews with Chilean runners (n=15) and running experts (n=6). Thematic analysis, guided by an interpretivist approach, uncovered intrinsic factors (identity, motivation, stress and self-learning) and extrinsic factors (environment, information sources, marketing, peer advice, professional guidance, racing, stereotype and clothing) that shaped runners’ behaviours. Less experienced runners associated injury risk with asphalt surfaces, faced challenges in discerning online information reliability and found motivation in peer advice. Experts emphasised the multifactorial nature of running-related injuries, including previous injuries and training-related factors. Both groups acknowledged a global tendency among runners to resist rest when discomfort arose. This research contributed to a nuanced understanding of injury perception, management and prevention, bridging scientific knowledge with individual experiences. Clinicians may use this information to enhance the therapy alliance and set realistic expectations about the runner’s rehabilitation process.
1Scopus© Citations 3
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Infectious diseases prevention and vaccination in migrants in Latin America: The challenges of transit through the treacherous Darien gap, Panama
(Elsevier BV, 2025-05)
Alfonso J. Rodriguez-Morales
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María Camila Puerta-Arias
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Rola Husni
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Juan J. Montenegro-Idrogo
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Juan Pablo Escalera-Antezana
Scopus© Citations 12 1
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Conditions favorables à l’engagement communautaire : évaluation participative de l’adaptation culturelle d’un programme de développement des filles au Sénégal, Afrique
(University of Toronto Press Inc. (UTPress), 2024-12-01)
QUIROZ SAAVEDRA, RODRIGO ANTONIO
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Judi Aubel
Les programmes pour le développement des jeunes se fondent sur les forces des jeunes et les facteurs environnementaux favorisant leur résilience. La recherche adopte une approche qualitative et participative, reposant sur des entretiens individuels, des groupes de discussion, et l’analyse participative. Les résultats révèlent que les participants jugent pertinent d’intégrer des éléments culturels et religieux (tels que la langue locale et les pratiques religieuses) dans la mise en œuvre de ce programme, et que ces éléments ont créé des conditions favorables à l’engagement communautaire. De plus, la combinaison des sources de données a permis de formaliser et mettre à l’épreuve l’approche axée sur la culture et la religion du programme étudié. Nous suggérons que cette étude permet de mieux cerner la responsabilité de l’évaluateur dans la mise en pratique d’une évaluation sensible à la culture lorsqu’il travail.
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SPINE20 Recommendations 2024 -Spinal Disability: Social Inclusion as a Key to Prevention and Management
(2024)
Cristiano M. Menezes
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Carlos Tucci
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Koji Tamai
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Harvinder S. Chhabra
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Fahad H. Alhelal
<jats:p> Spine disorders are the leading cause of disability worldwide. To promote social inclusion, it is essential to ensure that people can participate in their societies by improving their ability, opportunities, and dignity, through access to high-quality, evidence-based, and affordable spine services for all. </jats:p><jats:p> To achieve this goal, SPINE20 recommends six actions. </jats:p><jats:p> - SPINE20 recommends that G20 countries deliver evidence-based education to the community health workers and primary care clinicians to promote best practice for spine health, especially in underserved communities. </jats:p><jats:p> - SPINE20 recommends that G20 countries deliver evidence-based, high-quality, cost-effective spine care interventions that are accessible, affordable and beneficial to patients. </jats:p><jats:p> - SPINE20 recommends that G20 countries invest in Health Policy and System Research (HPSR) to generate evidence to develop and implement policies aimed at integrating rehabilitation in primary care to improve spine health. </jats:p><jats:p> - SPINE20 recommends that G20 countries support ongoing research initiatives on digital technologies including artificial intelligence, regulate digital technologies, and promote evidence-based, ethical digital solutions in all aspects of spine care, to enrich patient care with high value and quality. </jats:p><jats:p> - SPINE20 recommends that G20 countries prioritize social inclusion by promoting equitable access to comprehensive spine care through collaborations with healthcare providers, policymakers, and community organizations. </jats:p><jats:p> - SPINE20 recommends that G20 countries prioritize spine health to improve the well-being and productivity of their populations. Government health systems are expected to create a healthier, more productive, and equitable society for all through collaborative efforts and sustained investment in evidence-based care and promotion of spine health. </jats:p>
Scopus© Citations 7 1
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Subjective Well-being of Vulnerable Children in Chile: Differences by Gender and Risk Assessment
(2024)
Miguel Salazar-Muñoz
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Carmen Montserrat
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ALFARO INZUNZA, JAIME ANDRES
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MELIPILLAN ARANEDA, EDMUNDO ROBERTO
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Methodology of the joint malaria prevention recommendations of Switzerland, Germany, Belgium and The Netherlands
(2024)
Olivia Veit
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Ula Maniewski-Kelner
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Camilla Rothe
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Gilles Eperon
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Margarita Boering
<jats:p>The expert committees for travel medicine of Belgium, Germany, The Netherlands and Switzerland endorse joint malaria prevention recommendations for travellers. Here, the methodological approach underlying these recommendations, including evidence sources used, risk category definitions and the role of expert opinion, is outlined.</jats:p>
Scopus© Citations 2
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Accelerating Medicines Partnership® Schizophrenia (AMP® SCZ): Rationale and Study Design of the Largest Global Prospective Cohort Study of Clinical High Risk for Psychosis
(2024)
Cassandra M J Wannan
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Barnaby Nelson
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Jean Addington
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Kelly Allott
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Alan Anticevic
<jats:title>Abstract</jats:title> <jats:p>This article describes the rationale, aims, and methodology of the Accelerating Medicines Partnership® Schizophrenia (AMP® SCZ). This is the largest international collaboration to date that will develop algorithms to predict trajectories and outcomes of individuals at clinical high risk (CHR) for psychosis and to advance the development and use of novel pharmacological interventions for CHR individuals. We present a description of the participating research networks and the data processing analysis and coordination center, their processes for data harmonization across 43 sites from 13 participating countries (recruitment across North America, Australia, Europe, Asia, and South America), data flow and quality assessment processes, data analyses, and the transfer of data to the National Institute of Mental Health (NIMH) Data Archive (NDA) for use by the research community. In an expected sample of approximately 2000 CHR individuals and 640 matched healthy controls, AMP SCZ will collect clinical, environmental, and cognitive data along with multimodal biomarkers, including neuroimaging, electrophysiology, fluid biospecimens, speech and facial expression samples, novel measures derived from digital health technologies including smartphone-based daily surveys, and passive sensing as well as actigraphy. The study will investigate a range of clinical outcomes over a 2-year period, including transition to psychosis, remission or persistence of CHR status, attenuated positive symptoms, persistent negative symptoms, mood and anxiety symptoms, and psychosocial functioning. The global reach of AMP SCZ and its harmonized innovative methods promise to catalyze the development of new treatments to address critical unmet clinical and public health needs in CHR individuals.</jats:p>
Scopus© Citations 61 10
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Prevención de la infección por virus respiratorio sincicial en lactantes. ¿Qué se ha hecho y en qué estamos hoy?
(2023)
Jose M. Novoa Pizarro
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Birte Christina Lindemann Tappert
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Vivian R. Luchsinger Farias
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Sergio L. Vargas Munita
La infección por virus respiratorio sincicial (VRS) es causa frecuente de morbimortalidad en niños. Recientemente se han logrado grandes avances en el desarrollo de nuevos anticuerpos monoclonales y vacunas gracias al reconocimiento de la conformación estructural de proteínas del virus. El objetivo de este estudio es revisar los avances relacionados con la prevención de VRS en los primeros 6 meses de vida. Avances en biología estructural han demostrado que la proteína de fusión del VRS (Proteína F) en su conformación prefusión (Pre-F) constituye un excelente antígeno para desarrollar anticuerpos monoclonales y vacunas para prevenir infecciones por virus respiratorio sincicial (VRS). Un nuevo anticuerpo monoclonal de dosis única, nirsevimab, tiene mayor poder neutralizante que palivizumab actualmente disponible, y una protección prolongada por 5-6 meses. Nirsevimab tiene eficacia demostrada de 76,8 % (IC 95%: 49,4-89,4) para prevenir infección respiratoria baja a 150 días después de la inyección, disminuyendo el riesgo de hospitalizarse en UCI en un 90,1% (IC 95%: 16,4- 98,8). Clesrovimab es otro anticuerpo monoclonal, de dosis única, que también ha presentado promisorios resultados en los ensayos fase 1b-2a. Mas recientemente se ha desarrollado, replicando con ingeniería genética, la proteína F estabilizada en su estado Pre-F como antígeno, una vacuna bivalente contra VRS A y B (Bivalent Prefusion F) la que, administrada a embarazadas, entre las 24-36 semanas de gestación, induce altos niveles de anticuerpos maternos con elevado traspaso transplacentario al feto. Esta vacuna ha demostrado una eficacia de 81,8% (IC 95%: 40,6-96,3) a 90 días y de 69,4% (IC 95%: 44,3-84,1) a 180 días para prevenir enfermedad grave por VRS sin eventos de seguridad detectados hasta el momento. Estos desarrollos confieren protección efectiva mediante inmunidad pasiva contra VRS que dura los primeros 5-6 meses de vida, y tanto en el caso de nirsevimab como la vacuna PreF para embarazadas ya ha sido aprobado para su uso en Europa por EMA, Canadá y en Estados Unidos por la FDA.
13Scopus© Citations 2
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Challenges for the prevention of hypertension among international migrants in Latin America: prioritizing the health of migrants in healthcare systems
(2024)
Isabel Rada
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CABIESES VALDES, BALTICA BEATRIZ
<jats:p>Among the health priorities of international migrants, non-communicable diseases such as hypertension are of major interest due to their increasing prevalence, mainly in low- and middle-income countries. Previous evidence has reported a significant risk of hypertension in international migrants derived from multiple exposures during the migration process and at the destination, such as living conditions, health literacy and access to preventive services. Also, poorer disease control has been found compared to the local population. Considering existing deficiencies in access and use of healthcare services related to hypertension prevention and continuity of care of migrants globally, we aimed to offer a Latin American perspective of the challenges faced by international migrants residing in Latin America in accessing hypertension preventive care from a human rights, equity, and universal primary healthcare approaches. From a health systems perspective, we conducted a scoping review of scientific literature on hypertension prevention and control among international migrants in Latin America and the Caribbean. Based on the findings, we discuss the potential influence of migration and health policies on healthcare systems and individual and structural barriers to healthcare access, including lack of insurance, linguistic barriers, limited intercultural competence, and geographical and financial barriers. From existing evidence related to hypertension, we highlight the particular healthcare needs of migrants and their implications for regional public health goals. This aligns with promoting culturally tailored interventions considering the migration process, lifestyle patterns, structural vulnerabilities, and gender particularities in hypertension prevention, diagnosis, and treatment. We advocate for developing universal, voluntary, and systemic regional screening and disease control initiatives in Latin America for hypertension and other chronic conditions.</jats:p>
8Scopus© Citations 4

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