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Author: search.filters.author.Nilton CustodioSubject: search.filters.subject.dementia

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    Qualitative and quantitative educational disparities and brain signatures in healthy aging and dementia across global settings
    (Elsevier BV, 2025-04)
    Raul Gonzalez-Gomez
    ;
    Josephine Cruzat
    ;
    Hernán Hernández
    ;
    Joaquín Migeot
    ;
    Agustina Legaz
    Scopus© Citations 4  3
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    Biomarkers for dementia in Latin American countries: Gaps and opportunities
    (2022)
    Mario A. Parra
    ;
    ORELLANA VILLENA, VIVIANA PAULINA  
    ;
    Tomas Leon
    ;
    Cabello G. Victoria
    ;
    Rodrigo Gomez
      1Scopus© Citations 32  2
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    The Multi-Partner Consortium to Expand Dementia Research in Latin America (ReDLat): Driving Multicentric Research and Implementation Science
    (2021)
    Agustin Ibanez
    ;
    Jennifer S. Yokoyama
    ;
    Katherine L. Possin
    ;
    Diana Matallana
    ;
    Francisco Lopera
    <jats:p>Dementia is becoming increasingly prevalent in Latin America, contrasting with stable or declining rates in North America and Europe. This scenario places unprecedented clinical, social, and economic burden upon patients, families, and health systems. The challenges prove particularly pressing for conditions with highly specific diagnostic and management demands, such as frontotemporal dementia. Here we introduce a research and networking initiative designed to tackle these ensuing hurdles, the Multi-partner consortium to expand dementia research in Latin America (ReDLat). First, we present ReDLat's regional research framework, aimed at identifying the unique genetic, social, and economic factors driving the presentation of frontotemporal dementia and Alzheimer's disease in Latin America relative to the US. We describe ongoing ReDLat studies in various fields and ongoing research extensions. Then, we introduce actions coordinated by ReDLat and the Latin America and Caribbean Consortium on Dementia (LAC-CD) to develop culturally appropriate diagnostic tools, regional visibility and capacity building, diplomatic coordination in local priority areas, and a knowledge-to-action framework toward a regional action plan. Together, these research and networking initiatives will help to establish strong cross-national bonds, support the implementation of regional dementia plans, enhance health systems' infrastructure, and increase translational research collaborations across the continent.</jats:p>
    Scopus© Citations 53  9
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    Dementia in Latin America: Paving the way toward a regional action plan
    (2020)
    Mario Alfredo Parra
    ;
    Sandra Baez
    ;
    Lucas Sedeño
    ;
    Cecilia Gonzalez Campo
    ;
    Hernando Santamaría‐García
      2Scopus© Citations 115
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    Validation of Picture Free and Cued Selective Reminding Test for Illiteracy in Lima, Peru
    (2022)
    Rosa Montesinos
    ;
    Jose F. Parodi
    ;
    Monica M. Diaz
    ;
    Eder Herrera-Perez
    ;
    Elizabeth Valeriano-Lorenzo
    <jats:p> Dementia in Latin America is a crucial public health problem. Identifying brief cognitive screening (BCS) tools for the primary care setting is crucial, particularly for illiterate individuals. We evaluated tool performance characteristics and validated the free and total recall sections of the Free and Cued Selective Reminding Test-Picture version (FCSRT-Picture) to discriminate between 63 patients with early Alzheimer’s disease dementia (ADD), 60 amnestic mild cognitive impairment (aMCI) and 64 cognitively healthy Peruvian individuals with illiteracy from an urban area. Clinical, functional, and cognitive assessments were performed. FCSRT-Picture performance was assessed using receiver operating characteristic curve analyses. The mean ± standard deviation scores were 7.7 ± 1.0 in ADD, 11.8 ± 1.6 in aMCI, and 29.5 ± 1.8 in controls. The FCSRT-Picture had better performance characteristics for distinguishing controls from aMCI compared with several other BCS tools, but similar characteristics between controls and early ADD. The FCSRT-Picture is a reliable BCS tool for illiteracy in Peru. </jats:p>
    Scopus© Citations 4  1
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    Systematic Review of the Diagnostic Validity of Brief Cognitive Screenings for Early Dementia Detection in Spanish-Speaking Adults in Latin America
    (2020)
    Nilton Custodio
    ;
    Lissette Duque
    ;
    Rosa Montesinos
    ;
    Carlos Alva-Diaz
    ;
    Martin Mellado
      2Scopus© Citations 45
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    Scopus© Citations 107  13
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    The power of knowledge about dementia in Latin America across health professionals working on aging
    (2020)
    Agustin Ibanez
    ;
    Daniel Flichtentrei
    ;
    Eugenia Hesse
    ;
    Martin Dottori
    ;
    Ailin Tomio
      21Scopus© Citations 20