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Risk factors and outcomes of pediatric non-invasive respiratory support failure in Latin America
(2024)
Diana Paola Escobar-Serna
;
Juan Sebastian Barajas-Romero
;
Juan Javier Peralta-Palmezano
;
Juan Camilo Jaramillo-Bustamante
;
Nicolas Monteverde-Fernandez
2
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No one is better than all together: the role of networks in pediatric intensive care
(2019)
Sebastián González-Dambrauskas
;
Juan Camilo Jaramillo-Bustamante
;
Franco Díaz
1Scopus© Citations 5
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Therapeutic variability in infants admitted to Latin-American pediatric intensive units due to acute bronchiolitis
(2020)
Jesús Alberto Serra
;
Sebastián González-Dambrauskas
;
Pablo Vásquez Hoyos
;
CARVAJAL BENAVIDES, CÉSAR CRISTÓBAL
;
Alejandro Donoso
<jats:p>Objetivo: describir las terapias utilizadas en lactantes con bronquiolitis aguda admitidos en 20 Unidades de Cuidados Intensivos (UCI) pediátricos miembros de LARed en 5 países latinoamericanos.Pacientes y Método: Estudio observacional retrospectivo, multicéntrico, de datos del Registro Latinoamericano de Falla Respiratoria Aguda Pediátrica. Se incluyeron niños menores de 2 años ingresados a UCI pediátrica por bronquiolitis aguda comunitaria entre mayo-septiembre 2017. Se recolectaron datos demográficos, clínicos, soporte respiratorio, terapias utilizadas y resultados clínicos. Se realizó análisis de subgrupos según ubicación geográfica, tipo financiación y presencia de academia.Resultados: Ingresaron al registro 1.155 pacientes con falla respiratoria aguda. Seis casos fueron excluidos por no tener formulario completo. De los 1.147 pacientes, 908 eran menores de 2 años. De ellos, 467 tuvieron diagnóstico de bronquiolitis aguda, correspondiendo a la principal causa de ingreso a UCI pediátrica por falla respiratoria aguda (51,4%). Las características demográficas y de gravedad entre los centros fueron similares. El soporte máximo respiratorio más frecuente fue cánula nasal de alto flujo (47%), seguido por ventilación mecánica no invasiva (26%) y ventilación mecánica invasiva (17%), con un coeficiente de variación (CV) amplio entre los centros. Hubo una gran dispersión en uso de terapias, siendo frecuente el uso de broncodilatadores, antibióticos y corticoides, con CV hasta 400%. El análisis de subgrupos mostró diferencias significativas en soporte respiratorio y tratamientos utilizados. Un paciente falleció en esta cohorte.Conclusión: Detectamos gran variabilidad en el soporte respiratorio y tratamientos entre UCI pediátricas latinoamericanas. Esta variabilidad no es explicada por disparidades demográficas ni clínicas. Esta heterogeneidad de tratamientos debería promover iniciativas colaborativas para disminuir la brecha entre la evidencia científica y la práctica asistencial.</jats:p>
3Scopus© Citations 11
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Pediatric Inflammatory Multisystem Syndrome Associated With SARS-CoV-2
(2020)
Raúl Bustos B
;
Juan Camilo Jaramillo-Bustamante
;
Pablo Vasquez-Hoyos
;
Pablo Cruces
;
Franco Díaz
13Scopus© Citations 24
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Reduced PICU respiratory admissions during COVID-19
(2020)
Pablo Vásquez-Hoyos
;
Franco Diaz-Rubio
;
Nicolas Monteverde-Fernandez
;
Juan Camilo Jaramillo-Bustamante
;
CARVAJAL BENAVIDES, CÉSAR CRISTÓBAL
<jats:sec><jats:title>Background</jats:title><jats:p>The COVID-19 pandemic reached the Southern Hemisphere in the autumn of 2020, thus coinciding with its expected annual viral respiratory season. The potential impact of national strategies aimed at mitigating COVID-19 during the pandemic on the incidence of other critical viral lower respiratory tract infections (LRTIs) in children is unknown.</jats:p></jats:sec><jats:sec><jats:title>Methods</jats:title><jats:p>We analysed admission data for LRTIs from 22 paediatric intensive care units (PICUs) in four countries, part of a large international Latin American registry of children with acute respiratory failure (Red Colaborativa Pediátrica de Latinoamérica [LARed Network]).</jats:p></jats:sec><jats:sec><jats:title>Results</jats:title><jats:p>Between January and August, there were 83% fewer PICU admissions for LRTIs in 2020 compared to the 2018/2019 average over the same period. Similar decreases were noted for PICU admissions due to respiratory syncytial virus and influenza (92% and 78%, respectively).</jats:p></jats:sec><jats:sec><jats:title>Conclusion</jats:title><jats:p>We observed a striking reduction in PICU admissions due to viral LRTIs over winter, during the COVID-19 pandemic in South America.</jats:p></jats:sec>
Scopus© Citations 59 1
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Latin American Consensus on the Management of Sepsis in Children: Sociedad Latinoamericana de Cuidados Intensivos Pediátricos [Latin American Pediatric Intensive Care Society] (SLACIP) Task Force: Executive Summary
(2021)
Jaime Fernández-Sarmiento
;
Daniela Carla De Souza
;
Anacaona Martinez
;
Victor Nieto
;
Jesús López-Herce
<jats:p> Objective: The aim of this study was to develop evidence-based recommendations for the diagnosis and treatment of sepsis in children in low- and middle-income countries (LMICs), more specifically in Latin America. Design: A panel was formed consisting of 27 experts with experience in the treatment of pediatric sepsis and two methodologists working in Latin American countries. The experts were organized into 10 nominal groups, each coordinated by a member. Methods: A formal consensus was formed based on the modified Delphi method, combining the opinions of nominal groups of experts with the interpretation of available scientific evidence, in a systematic process of consolidating a body of recommendations. The systematic search was performed by a specialized librarian and included specific algorithms for the Cochrane Specialized Register, PubMed, Lilacs, and Scopus, as well as for OpenGrey databases for grey literature. The GRADEpro GDT guide was used to classify each of the selected articles. Special emphasis was placed on search engines that included original research conducted in LMICs. Studies in English, Spanish, and Portuguese were covered. Through virtual meetings held between February 2020 and February 2021, the entire group of experts reviewed the recommendations and suggestions. Result: At the end of the 12 months of work, the consensus provided 62 recommendations for the diagnosis and treatment of pediatric sepsis in LMICs. Overall, 60 were strong recommendations, although 56 of these had a low level of evidence. Conclusions: These are the first consensus recommendations for the diagnosis and management of pediatric sepsis focused on LMICs, more specifically in Latin American countries. The consensus shows that, in these regions, where the burden of pediatric sepsis is greater than in high-income countries, there is little high-level evidence. Despite the limitations, this consensus is an important step forward for the diagnosis and treatment of pediatric sepsis in Latin America. </jats:p>
8Scopus© Citations 32

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