Latin American Consensus on the Management of Sepsis in Children: Sociedad Latinoamericana de Cuidados Intensivos Pediátricos [Latin American Pediatric Intensive Care Society] (SLACIP) Task Force: Executive Summary
Journal
Journal of Intensive Care Medicine
ISSN
0885-0666
1525-1489
Date Issued
2021
Author(s)
Jaime Fernández-Sarmiento
Daniela Carla De Souza
Anacaona Martinez
Victor Nieto
Jesús López-Herce
Vanessa Soares Lanziotti
María del Pilar Arias López
Werther Brunow De Carvalho
Claudio F. Oliveira
Juan Camilo Jaramillo-Bustamante
Adriana Yock-Corrales
Silvina Ruvinsky
Manuel Munaico
Viviana Pavlicich
Ricardo Iramain
Marta Patricia Márquez
Gustavo González
Mauricio Yunge
Cristian Tonial
Pablo Cruces
Gladys Palacio
Carolina Grela
Maria Slöcker-Barrio
Santiago Campos-Miño
Sebastian González-Dambrauskas
Nelson L Sánchez-Pinto
Pedro Celiny García
Roberto Jabornisky
Type
Resource Types::text::journal::journal article
URL Institutional Repository
Abstract
<jats:p> Objective: The aim of this study was to develop evidence-based recommendations for the diagnosis and treatment of sepsis in children in low- and middle-income countries (LMICs), more specifically in Latin America. Design: A panel was formed consisting of 27 experts with experience in the treatment of pediatric sepsis and two methodologists working in Latin American countries. The experts were organized into 10 nominal groups, each coordinated by a member. Methods: A formal consensus was formed based on the modified Delphi method, combining the opinions of nominal groups of experts with the interpretation of available scientific evidence, in a systematic process of consolidating a body of recommendations. The systematic search was performed by a specialized librarian and included specific algorithms for the Cochrane Specialized Register, PubMed, Lilacs, and Scopus, as well as for OpenGrey databases for grey literature. The GRADEpro GDT guide was used to classify each of the selected articles. Special emphasis was placed on search engines that included original research conducted in LMICs. Studies in English, Spanish, and Portuguese were covered. Through virtual meetings held between February 2020 and February 2021, the entire group of experts reviewed the recommendations and suggestions. Result: At the end of the 12 months of work, the consensus provided 62 recommendations for the diagnosis and treatment of pediatric sepsis in LMICs. Overall, 60 were strong recommendations, although 56 of these had a low level of evidence. Conclusions: These are the first consensus recommendations for the diagnosis and management of pediatric sepsis focused on LMICs, more specifically in Latin American countries. The consensus shows that, in these regions, where the burden of pediatric sepsis is greater than in high-income countries, there is little high-level evidence. Despite the limitations, this consensus is an important step forward for the diagnosis and treatment of pediatric sepsis in Latin America. </jats:p>
Cite this document
Fernández-Sarmiento, J., De Souza, D. C., Martinez, A., Nieto, V., López-Herce, J., Soares Lanziotti, V., Arias López, M. D. P., De Carvalho, W. B., Oliveira, C. F., Jaramillo-Bustamante, J. C., Díaz, F., Yock-Corrales, A., Ruvinsky, S., Munaico, M., Pavlicich, V., Iramain, R., Márquez, M. P., González, G., Yunge, M., … Jabornisky, R. (2022). Latin american consensus on the management of sepsis in children: Sociedad latinoamericana de cuidados intensivos pediátricos [latin american pediatric intensive care society] (Slacip) task force: executive summary. Journal of Intensive Care Medicine, 37(6), 753-763. https://doi.org/10.1177/08850666211054444
Subjects
bolus
;
bundle
;
children
;
consensus
;
fluid therapy
;
pediatrics
;
sepsis
;
septic shock
;
vasopressor agents
;
child
;
consensus
;
critical care
;
humans
;
latin america
;
sepsis
;
amphotericin b lipid complex
;
antibiotic agent
;
c reactive protein
;
cephalosporin
;
echinocandin
;
ferritin
;
hydrocortisone
;
hypertensive agent
;
omega 3 fatty acid
;
procalcitonin
;
sodium
;
adjuvant therapy
;
antigen antibody reaction
;
article
;
blood pressure
;
child
;
electrocardiogram
;
endotracheal intubation
;
fluid therapy
;
gastrointestinal infection
;
health care facility
;
health care organization
;
heart output
;
hemodynamics
;
human
;
intensive care unit
;
invasive ventilation
;
lactate blood level
;
latin american consensus on the management of sepsis in children
;
latin american pediatric intensive care society
;
morbidity
;
mortality
;
noninvasive ventilation
;
organ dysfunction score
;
oxygen saturation
;
pediatric index of mortality
;
respiratory function
;
respiratory tract infection
;
resuscitation
;
sepsis
;
socioeconomics
;
urine volume
;
consensus
;
intensive care
;
procedures
;
sepsis
;
south and central america