Universidad del Desarrollo

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Rethinking the Schenck Classification for Multiligament Knee Injuries: Evaluating Whether the Schenck KD Grade Is Associated With the Presence of Vascular or Neurological Injuries in a Multicenter Study With 144 Patients
(SAGE Publications, 2025-03)
Enrique Sanchez-Munoz
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Beatriz Lozano Hernanz
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Renato Andrade
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Cristina Valente
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João Espregueira-Mendes
Scopus© Citations 2 1
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Spatial navigation entropy suggests allocentric dysfunction in PPPD
(Frontiers Media SA, 2025-05-16)
Felipe Faúndez
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Camilo Arévalo-Romero
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Karen Villarroel
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Gustavo Vial
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Claudio Lavín
Persistent postural-perceptual dizziness (PPPD) is a common chronic dizziness disorder with an unclear pathophysiology. It is hypothesized that PPPD may involve functional dysfunction of the construction of inner cognitive maps, leading to disrupted spatial cognition processes as a core feature. The present studies attempt to unravel the neural mechanisms that underlie spatial navigation in PPPD.</jats:p></jats:sec><jats:sec><jats:title>Methods</jats:title><jats:p>Fifty-two participants completed the study: 19 PPPD patients, 20 control subjects with vestibular disorders but without PPPD (with comparable peripheral vestibular function to the PPPD group, and 13 healthy volunteers). All underwent a virtual Morris Water Maze (vMWM) task in both, non-immersive (NI) and virtual reality (VR) modalities, assessing spatial navigation performance, gaze behavior, and head kinematics.</jats:p></jats:sec><jats:sec><jats:title>Results</jats:title><jats:p>PPPD patients exhibited significantly worse navigation performance than both control groups across all metrics, with greater impairments in predominantly allocentric tasks. They also showed increased exploratory gaze behavior, unaffected by NI vs. VR modality or task condition. Head kinematics did not significantly differ between the three groups, though a non-significant trend indicated reduced head movement in both PPPD and vestibular controls. VR intolerance was highest in PPPD patients, followed by vestibular controls, with healthy volunteers showing the lowest discomfort.</jats:p></jats:sec><jats:sec><jats:title>Discussion</jats:title><jats:p>Our findings suggest that PPPD involves deficits in allocentric spatial navigation, likely due to predictive coding errors and impaired internal model updating, rather than sensory input dysfunction. Increased gaze scanning may reflect compensatory mechanisms for spatial uncertainty. Notably, VR immersion did not alter navigation performance, suggesting visuo-vestibular conflict is not the primary driver of PPPD-related spatial deficits. These findings offer new insights into PPPD as a disorder of spatial cognition, opening avenues for novel diagnostic and therapeutic approaches.
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Neuromyelitis optica spectrum disorder in Latin America: a global data share initiative
(Elsevier BV, 2025-06)
Juan I. Rojas
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Liliana Patrucco
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Edgardo Cristiano
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José I. Gortari
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Paola A. Ortiz Salas
Scopus© Citations 2 1
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White matter volume and microstructural integrity are associated with fatigue in relapsing multiple sclerosis
(Springer Science and Business Media LLC, 2025-05-12)
FIGUEROA VARGAS, ALEJANDRA MABEL
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Sebastián Navarrete-Caro
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Claudia Cárcamo
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Ethel Ciampi
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Macarena Vásquez-Torres
10
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How I Do It: Evaluating Cardiac Implantable Devices and Noncardiac Mimics on Chest Radiographs
(Radiological Society of North America (RSNA), 2025-05-01)
SILVA FUENTE ALBA, CLAUDIO SERGIO
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Jared D. Christensen
This article provides a comprehensive review of the radiographic appearances of cardiac implantable electronic devices, other cardiac support apparatuses, and similar-appearing noncardiac devices, emphasizing the importance of accurate identification and evaluation for potential complications.
6
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Magnetic resonance imaging of paraurethral and paravaginal lesion: relevant diagnoses, key findings and surgical correlation
(AME Publishing Company, 2025-05)
Andrés Labra
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Rolando Cocio
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Álvaro Saavedra
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Giancarlo Schiappacasse
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Fernanda Blaskovic
11
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Update in the imaging study of multiple myeloma
(Publicidad Permanyer, SLU, 2024-09-30)
BARAHONA ZULETA, DANIELA FRANCESCA
1
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Lateral prefrontal theta oscillations causally drive a computational mechanism underlying conflict expectation and adaptation
(2024)
María Paz Martínez-Molina
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Gabriela Valdebenito-Oyarzo
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SOTO ICAZA, PATRICIA
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Francisco Zamorano
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Antoni Valero-Cabré
Scopus© Citations 3 8
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The BrainLat project, a multimodal neuroimaging dataset of neurodegeneration from underrepresented backgrounds
(2023)
Pavel Prado
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Vicente Medel
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Raul Gonzalez-Gomez
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Agustín Sainz-Ballesteros
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Victor Vidal
The Latin American Brain Health Institute (BrainLat) has released a unique multimodal neuroimaging dataset of 780 participants from Latin American. The dataset includes 530 patients with neurodegenerative diseases such as Alzheimer’s disease (AD), behavioral variant frontotemporal dementia (bvFTD), multiple sclerosis (MS), Parkinson’s disease (PD), and 250 healthy controls (HCs). This dataset (62.7 ± 9.5 years, age range 21–89 years) was collected through a multicentric effort across five Latin American countries to address the need for affordable, scalable, and available biomarkers in regions with larger inequities. The BrainLat is the first regional collection of clinical and cognitive assessments, anatomical magnetic resonance imaging (MRI), resting-state functional MRI (fMRI), diffusion-weighted MRI (DWI), and high density resting-state electroencephalography (EEG) in dementia patients. In addition, it includes demographic information about harmonized recruitment and assessment protocols. The dataset is publicly available to encourage further research and development of tools and health applications for neurodegeneration based on multimodal neuroimaging, promoting the assessment of regional variability and inclusion of underrepresented participants in research.
30Scopus© Citations 22
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Síndrome de hipertensión intracraneana como manifestación inhabitual del síndrome de Sjögren. Caso clínico
(2023)
Dominga García
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Cristián Labarca
5

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