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Item type:Publication, Infectious diseases prevention and vaccination in migrants in Latin America: The challenges of transit through the treacherous Darien gap, Panama(Elsevier BV, 2025-05) ;Alfonso J. Rodriguez-Morales ;María Camila Puerta-Arias ;Rola Husni ;Juan J. Montenegro-IdrogoJuan Pablo Escalera-AntezanaScopus© Citations 12 1 - Some of the metrics are blocked by yourconsent settings
Item type:Publication, Hantavirus in humans: a review of clinical aspects and management(2023) ;Pablo A Vial ;Marcela Ferrés; ;Jonas KlingströmClas AhlmScopus© Citations 77 79 - Some of the metrics are blocked by yourconsent settings
Item type:Publication, Assessing Pulmonary Epithelial Damage in Hantavirus Cardiopulmonary Syndrome: Challenging the Predominant Role of Vascular Endothelium through sRAGE as a Potential Biomarker(2023) ;Gabriela Meza-Fuentes; ; ; Hantavirus cardiopulmonary syndrome (HCPS) is a severe respiratory illness primarily associated with microvascular endothelial changes, particularly in the lungs. However, the role of the pulmonary epithelium in HCPS pathogenesis remains unclear. This study explores the potential of soluble Receptors for Advanced Glycation End-products (sRAGE) as a biomarker for assessing pulmonary epithelial damage in severe HCPS, challenging the prevailing view that endothelial dysfunction is the sole driver of this syndrome. We conducted a cross-sectional study on critically ill HCPS patients, categorizing them into mild HCPS, severe HCPS, and negative control groups. Plasma sRAGE levels were measured, revealing significant differences between the severe HCPS group and controls. Our findings suggest that sRAGE holds promise as an indicator of pulmonary epithelial injury in HCPS and may aid in tracking disease progression and guiding therapeutic strategies. This study brings clarity on the importance of investigating the pulmonary epithelium’s role in HCPS pathogenesis, offering potential avenues for enhanced diagnostic precision and support in this critical public health concern.1 - Some of the metrics are blocked by yourconsent settings
Item type:Publication, Proteinuria in Hantavirus Cardiopulmonary Syndrome: A Frequent Finding Linked To Mortality(2021); ;Gregory Mertz; ;Mauricio EspinozaMarcela Ferrés27Scopus© Citations 4 - Some of the metrics are blocked by yourconsent settings
Item type:Publication, Under five and infant mortality in Chile (1990-2016): Trends, disparities, and causes of death(2020); ;Gloria Icaza; ;Loreto VillanuevaScopus© Citations 15 1 - Some of the metrics are blocked by yourconsent settings
Item type:Publication, Cien años de salud en un contexto demográfico, epidemiológico y de políticas públicas: la transición de la morbilidad infantil y sus desafíos(2022) ;Luisa Schonhaut B. ;Ana Zepeda O.Paula Rojas B.<jats:p>Chile se encuentra en una etapa avanzada de la transición demográfica y epidemiológica. Es ese escenario sobrevino la crisis política, económica y sanitaria, con el estallido social el 2019 y luego la pandemia de COVID-19. La mortalidad de niños(as) y adolescentes cayó significativamente, no obstante, los cambios en los estilos de vida y la desmotivación, asociada a largo confinamiento y empeoramiento de la salud de los padres y cuidadores desencadenaron una epidemia de problemas de salud mental, del desarrollo y nutricionales. Los pediatras se tuvieron que reinventar, exponiéndose al distrés y burnout. El objetivo del manuscrito es describir el contexto demográfico, epidemiológico y de políticas públicas de la salud infantil en Chile en el último siglo, como telón de fondo para dimensionar el impacto inmediato de la pandemia de COVID-19. Se discuten los nuevos desafíos en la salud para este grupo etario a mediano y largo plazo. Se exponen algunas teorías, conceptualizaciones e hitos relevantes del sistema de la salud pública en Chile. Se plantea la emergencia de “morbilidad post-pandemia”, como son el sedentarismo, inseguridad alimentaria, adicción a las pantallas, conflictos de identidad, violencia, trastornos en la esfera de la salud mental y reemergencia de morbimortalidad por enfermedades infectocontagiosas. Los profesionales encargados del cuidado de los niños tienen que redoblar sus esfuerzos para otorgar una atención integral, acompañando a las familias en los nuevos desafíos, para rehabilitar una infancia saludable.</jats:p>8Scopus© Citations 3 - Some of the metrics are blocked by yourconsent settings
Item type:Publication, Epidemic preparedness in urban settings: new challenges and opportunities(2020) ;Vernon J Lee ;Marc Ho ;Chen Wen Kai; David Heymann17Scopus© Citations 93 - Some of the metrics are blocked by yourconsent settings
Item type:Publication, Preparedness for emerging epidemic threats: a Lancet Infectious Diseases Commission(2020) ;Vernon J Lee; ;David Heymann ;Annelies Wilder-SmithVernon J. Lee8Scopus© Citations 55 - Some of the metrics are blocked by yourconsent settings
Item type:Publication, The human microbiota and infection prevention(2019); Erika M.C. D’Agata<jats:title>Abstract</jats:title><jats:p>The human microbiome participates in numerous aspects of human physiology and disease states. Recently, studies have begun to explore the role of the microbiome in colonization, infection and transmission of pathogens. This review provides a summary of the methodological principles used in microbiome studies and the published evidence of the impact of microbiome dysbiosis in infection prevention.</jats:p>Scopus© Citations 12 1