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Item type:Publication, Respiratory mechanics in infants with severe bronchiolitis on controlled mechanical ventilation(2017) ;Pablo Cruces ;Sebastián González-Dambrauskas ;Julio Quilodrán ;Jorge ValenzuelaJavier MartínezScopus© Citations 27 2 - Some of the metrics are blocked by yourconsent settings
Item type:Publication, Severe pertussis: State of the art(2012) ;Alejandro Donoso ;Daniela Arriagada Santis ;Pablo CrucesFranco Díaz1Scopus© Citations 17 - Some of the metrics are blocked by yourconsent settings
Item type:Publication, Sífilis congénita: presentación como shock séptico después del período neonatal(2012) ;Daniela Arriagada ;Alejandro Donoso ;Pablo CrucesFranco Díaz6Scopus© Citations 6 - Some of the metrics are blocked by yourconsent settings
Item type:Publication, Respiratory and hemodynamic effects of a stepwise lung recruitment maneuver in pediatric ARDS: A feasibility study(2012) ;Pablo Cruces ;Alejandro Donoso ;Jorge ValenzuelaFranco DíazBackgroundLittle is known about the efficacy and safety of recruitment maneuvers (RMs) in pediatric patients with acute respiratory distress syndrome (ARDS). We therefore assessed the effects on gas exchange and lung mechanics and the possible detrimental effects of a sequential lung RMs and decremental positive end-expiratory pressure (PEEP) titration in pediatric ARDS patients. MethodsWe enrolled patients <15 years of age with ARDS, progressive hypoxemia, <72hr of mechanical ventilation, and hemodynamic stability. A step-wise RM and decremental PEEP trial were performed. Safety was evaluated as the occurrence of hypotension and low pulse oxymeter oxygen saturation during the maneuver and development of airleaks after. Efficacy was evaluated as changes in lung compliance (C-dyn) and gas exchange 1, 12, and 24hr after the RM. ResultsWe included 25 patients, of median age 5 (1-16) months, median weight 7.0 (4.1-9.2)kg, median PaO2/FIO2 117 (96-139), and median C-dyn 0.48 (0.41-0.68)ml/cmH(2)O/kg at baseline. Thirty RM were performed, with all completed successfully. No airleaks developed. Mild hypotension was detected during four procedures. Following RM, C-dyn, and PaO2/FIO2 increased significantly (P<0.01 each), without changes in PaCO2 (P=0.4). A >25% improvement in lung function (C-dyn or PaO2/FIO2) was observed after 90% of the RM procedures. Gas exchange worsening over the next 24hr resulted in HFOV use in 36% of patients, while the remaining subjects sustained improvements in oxygenation at 12 and 24hr. The 28-day mortality rate was 16%. ConclusionsSequential RMs were safe and well tolerated in hemodynamically stable children with ARDS. RMs and a decremental PEEP trial may improve lung function in pediatric patients with ARDS and severe hypoxemia. Pediatr Pulmonol. 2013; 48:1135-1143. (c) 2012 Wiley Periodicals, Inc.3Scopus© Citations 31 - Some of the metrics are blocked by yourconsent settings
Item type:Publication, Characteristics of Medically Transported Critically Ill Children with Respiratory Failure in Latin America: Implications for Outcomes(2021) ;Jesus A. Serra ;Franco Díaz ;Pablo Cruces; Maria J. Nuñez<jats:title>Abstract</jats:title><jats:p>Several challenges exist for referral and transport of critically ill children in resource-limited regions such as Latin America; however, little is known about factors associated with clinical outcomes. Thus, we aimed to describe the characteristics of critically ill children in Latin America transferred to pediatric intensive care units for acute respiratory failure to identify risk factors for mortality. We analyzed data from 2,692 patients admitted to 28 centers in the Pediatric Collaborative Network of Latin America Acute Respiratory Failure Registry. Among patients referred from another facility (773, 28%), nonurban transports were independently associated with mortality (adjusted odds ratio = 9.4; 95% confidence interval: 2.4–36.3).</jats:p>4 - Some of the metrics are blocked by yourconsent settings
Item type:Publication, Mild hypothermia attenuates lung edema and plasma interleukin-1β in a rat mechanical ventilation-induced lung injury model(2011) ;Cruces, Pablo ;Ronco, Ricardo ;Benjamín Erranz; 33Scopus© Citations 9 - Some of the metrics are blocked by yourconsent settings
Item type:Publication, Angiotensin-converting enzyme insertion/deletion polymorphism is associated with severe hypoxemia in pediatric ARDS(2011) ;Pablo Cruces ;Franco Díaz ;Alonso Puga ;Benjamín ErranzAlejandro DonosoScopus© Citations 26 1 - Some of the metrics are blocked by yourconsent settings
Item type:Publication, Mild hypothermia increases pulmonary anti-inflammatory response during protective mechanical ventilation in a piglet model of acute lung injury(2013) ;Pablo Cruces ;Erranz, Benjamín ;Alejandro Donoso; Tatiana Salomón15Scopus© Citations 17 - Some of the metrics are blocked by yourconsent settings
Item type:Publication, Diferencia veno-arterial de dióxido de carbono como predictor de gasto cardiaco disminuido en modelo pediátrico experimental(2012) ;Franco Díaz ;Alejandro Donoso; ;Tatiana SalomónMaría Torres14 - Some of the metrics are blocked by yourconsent settings
Item type:Publication, Consideraciones geográficas en la interpretación de los resultados de revisiones sistemáticas y meta-análisis: fluidos en sepsis pediátrica(2019) ;Franco Díaz ;Sebastian Gonzalez-Dambrauskas ;Jan Hau LeePablo Cruces1Scopus© Citations 1
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