BEHRENS PELLEGRINO, MARIA ISABEL
Preferred name
BEHRENS PELLEGRINO, MARIA ISABEL
Official Name
BEHRENS PELLEGRINO, MARIA ISABEL
Main Affiliation
Email
mbehrens@udd.cl
ORCID
0000-0003-0964-426X
Scopus Author ID
7007110355
58 results
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Item type:Publication, The Impact of a Yoga-Based Mindfulness Intervention versus Psycho-Educational Session for Older Adults with Mild Cognitive Impairment: The Protocol of a Randomized Controlled Trial(2022) ;Maryam Farhang ;Graciela Rojas ;Pablo Martínez; Álvaro I. Langer<jats:p>Background: There is a global agreement in the medical community that a significant proportion of dementia cases could be prevented or postponed. One of the factors behind this agreement comes from scientific evidence showing that mind-body interventions such as mindfulness and yoga for the elderly have been related to a range of positive outcomes, including improved cognition performance in seniors with mild cognitive impairment (MCI). Objective: This study aims to evaluate the effectiveness of a yoga-based mindfulness intervention (YBM) versus psychoeducational sessions for older adults with MCI attending Hospital Clinic Universidad de Chile in Santiago. Method: Two-arm, individually randomized controlled trial (RCT) will be carried out at Clinical Hospital Universidad de Chile in Santiago. Older people over 60 years with any type of MCI using a score < 21 in the Montreal Cognitive Assessment (MoCA) test and a score of 0.05 in the Clinical Dementia Rating (CDR) Scale; and with preserved activities of daily living will be randomly assigned with an allocation ratio of 1:1 in either the yoga-based mindfulness intervention or the active control group based on the psycho-educational program. People who have performed yoga and/or mindfulness in the last 6 months or/and people with a psychiatric clinical diagnosis will be excluded from the study. Montreal Cognitive Assessment, the Lawton Instrumental Activities of Daily Living Scale (IADL), the Barthel Index (BI), the Pemberton happiness index, the Geriatric Anxiety Inventory (GAI) as well as the Geriatric Depression Scale (GDS-5) will be administered by blinded outcomes assessors before random assignment (Pre-test), the week following the last session of the intervention (post-test), and then after 3- and 6-months follow-up. Results: The YBM intervention protocol based on a video recording has been adapted and designed. This is the first RCT to examine the effects of a yoga-based mindfulness intervention in improving cognitive and physical functions and mental health outcomes for Chilean elderly diagnosed with MCI. It is expected to be implemented as an acceptable and effective non-pharmacological option for older people with MCI. Conclusion: Providing evidence-based programs such as preventive therapy for Alzheimer’s disease has relevant implications for public mental health services in Chile.</jats:p>Scopus© Citations 7 1 - Some of the metrics are blocked by yourconsent settings
Item type:Publication, Clinical spectrum of Kufor-Rakeb syndrome in the Chilean kindred with ATP13A2 mutations(2010); ;Norbert Brüggemann ;Pedro Chana ;Pablo VenegasMarianne Kägi6Scopus© Citations 106 - Some of the metrics are blocked by yourconsent settings
Item type:Publication, Increased susceptibility to oxidative death of lymphocytes from Alzheimer patients correlates with dementia severity(2014-03) ;Ponce, Daniela ;Salech, Felipe ;Sanmartin, Carol ;Silva, MónicaXiong, Chengjie3 - Some of the metrics are blocked by yourconsent settings
Item type:Publication, Author Correction: The BrainLat project, a multimodal neuroimaging dataset of neurodegeneration from underrepresented backgrounds(2024) ;Pavel Prado ;Vicente Medel ;Raul Gonzalez-Gomez ;Agustín Sainz-BallesterosVictor Vidal1Scopus© Citations 1 - Some of the metrics are blocked by yourconsent settings
Item type:Publication, 1278 Feasibility of 48-h Ambulatory BP Assessment in Latinos with Dementia(Oxford University Press (OUP), 2025-05) ;Mili Jimenez Gallardo ;Andrea Castillo Suárez ;Peng Li ;Ramon C HermidaMichael SmolenskyAbstract Introduction Ambulatory blood pressure (BP) monitoring encapsulates 24-h BP patterns across the sleep-wake cycle and provides a comprehensive assessment of BP regulation with certain features, such as sleep-time dipping, that can better predict health outcomes than traditional office BP measurements. However, 24-h BP patterns remain understudied in Latino populations, especially older adults. This pilot study investigated the feasibility of continuously ambulatory BP monitoring blood pressure with portable devices in Latinos with dementia. Methods Eight participants (4 with Alzheimer’s disease, 1 with Frontotemporal dementia, 3 controls; age range 45.8-80.3 years) from the ReDLat cohort (Multi-Partner Consortium to Expand Dementia Research in Latin America) were enrolled for a 48-h ambulatory BP assessment with hourly measurements using a portable arm-cuff device. Participants also answered six questions to evaluate: (1) device adaption, (2) measurement frequency tolerability, (3) study duration acceptability, (4) perceived value of the assessment, (5) willingness to perform the assessment again, and (6) likelihood of recommending the assessment to others. Results The study yielded high-quality recordings with minimal missing BP measurements (range: 0%-14.1%; mean: 8.9%). Device adaptation improved over time, with 75% (6/8) reporting better tolerance on the second day and 25% (2/8) reporting consistently good tolerance across both days. All participants reported that hourly BP measurement was tolerable, and majority (7/8, 87.5%) found 48-h monitoring acceptable. Seven participants (87.5%) believed that the assessment was valuable, were willing to participate again, and likely recommend to others the assessment. Conclusion Our findings demonstrate that 48-hour ambulatory BP monitoring is feasible and well-tolerated among older Latino adults with mild to moderate dementia in Latin American settings. Further feasibility testing should be performed in large samples and other populations, including individuals at later stages of dementia and in different countries.4 - Some of the metrics are blocked by yourconsent settings
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