The Ω-3 fatty acid docosahexaenoic acid selectively induces apoptosis in tumor-derived cells and suppress tumor growth in gastric cancer

Journal
European Journal of Pharmacology
ISSN
0014-2999
Date Issued
2021
Author(s)
Lorena Ortega
Lorena Lobos-González
Mauricio Reyna-Jeldes
Daniela Cerda
Erwin De la Fuente-Ortega
Patricio Castro
Giuliano Bernal
Claudio Coddou
Type
Resource Types::text::journal::journal article
Scopus ID
2-s2.0-85099907014
WoS ID
WOS:000623902800011
DOI
URL
URL Institutional Repository
Cite this document
Ortega, L., Lobos-González, L., Reyna-Jeldes, M., Cerda, D., De La Fuente-Ortega, E., Castro, P., Bernal, G., & Coddou, C. (2021). The Ω-3 fatty acid docosahexaenoic acid selectively induces apoptosis in tumor-derived cells and suppress tumor growth in gastric cancer. European Journal of Pharmacology, 896, 173910. https://doi.org/10.1016/j.ejphar.2021.173910
Subjects
gastric cancer

; 

omega-3 polyunsaturated fatty acids

; 

docosahexaenoic acid

; 

dha

; 

apoptosis

; 

adenocarcinoma

; 

animals

; 

antineoplastic agents

; 

apoptosis

; 

apoptosis regulatory proteins

; 

cell line, tumor

; 

cell proliferation

; 

docosahexaenoic acids

; 

female

; 

gene expression regulation, neoplastic

; 

humans

; 

male

; 

mice, inbred balb c

; 

mice, inbred nod

; 

mice, scid

; 

signal transduction

; 

stomach neoplasms

; 

tumor burden

; 

xenograft model antitumor assays

; 

arachidonic acid

; 

caspase 3

; 

caspase 7

; 

docosahexaenoic acid

; 

icosapentaenoic acid

; 

linolenic acid

; 

antineoplastic agent

; 

apoptosis regulatory protein

; 

docosahexaenoic acid

; 

ags cell line

; 

animal cell

; 

animal experiment

; 

animal model

; 

antineoplastic activity

; 

antiproliferative activity

; 

apoptosis

; 

article

; 

ascites

; 

concentration response

; 

controlled study

; 

female

; 

ges-1 cell line

; 

hematological parameters

; 

human

; 

human cell

; 

in vitro study

; 

in vivo study

; 

liver metastasis

; 

male

; 

mouse

; 

mtt assay

; 

nonhuman

; 

real time polymerase chain reaction

; 

staining

; 

stomach cancer

; 

treatment duration

; 

treatment outcome

; 

treatment response

; 

tumor volume

; 

western blotting

; 

adenocarcinoma

; 

animal

; 

apoptosis

; 

bagg albino mouse

; 

cell proliferation

; 

drug effect

; 

drug screening

; 

gene expression regulation

; 

genetics

; 

metabolism

; 

nonobese diabetic mouse

; 

pathology

; 

scid mouse

; 

signal transduction

; 

stomach tumor

; 

tumor cell line