Treatment of Patellofemoral Chondral Lesions Using Microfractures Associated with a Chitosan Scaffold: Mid-Term Clinical and Radiological Results
Journal
CARTILAGE
ISSN
1947-6035
1947-6043
Date Issued
2021
Author(s)
Martin Contreras
Nicolas Zilleruelo
Type
Resource Types::text::journal::journal article
URL Institutional Repository
Abstract
<jats:sec><jats:title>Objective</jats:title><jats:p> To assess the clinical and radiological results of patellofemoral osteochondral lesions treated with microfractures associated with a chitosan scaffold. </jats:p></jats:sec><jats:sec><jats:title>Design</jats:title><jats:p> A retrospective observational analytical study was performed. Fifteen patients with full-thickness patellofemoral osteochondral lesions were included. Quantity and quality of the reparation cartilage was assessed with the MOCART 2.0 score on a postoperative magnetic resonance imaging (MRI), and clinical outcomes were evaluated with pre- and postoperative Kujala score tests. Shapiro-Wilk test for normality was applied as well as Wilcoxon’s signed rank test and Kruskal-Wallis H test for clinical scores within subjects and patella versus trochlea subgroups comparisons. Analysis of variance test was used for imaging subgroups comparison, with P < 0.05 defined as statistical significance. </jats:p></jats:sec><jats:sec><jats:title>Results</jats:title><jats:p> Mean follow-up was 33.36 months (range 24-60 months). Postoperative Kujala scores improved an average of 19 points compared with the preoperative state (SE = 17.6; P < 0.001). No statistical difference was found through the clinical location assessment ( P = 0.756), as well as the cartilage imaging assessment ( P = 0.756). The mean MOCART 2.0 scale was 67.67 (range 50-85). </jats:p></jats:sec><jats:sec><jats:title>Conclusions</jats:title><jats:p> Treating full-thickness patellofemoral osteochondral lesions with microfractures associated with a chitosan scaffold proved to be effective regarding defect filling and symptomatic improvement. </jats:p></jats:sec>
Subjects
chitosan
;
cargel
;
patellofemoral
;
osteochondral
;
cartilage
;
cartilage, articular
;
chitosan
;
fractures, stress
;
humans
;
magnetic resonance imaging
;
patella
;
retrospective studies
;
tissue scaffolds
;
chitosan
;
scaffold protein
;
article
;
clinical assessment
;
clinical outcome
;
controlled study
;
female
;
follow up
;
human
;
kruskal wallis test
;
kujala score test
;
male
;
microfracture (procedure)
;
nuclear magnetic resonance imaging
;
observational study
;
outcome assessment
;
patellofemoral joint
;
preoperative evaluation
;
radiology
;
retrospective study
;
shapiro wilk test
;
wilcoxon signed ranks test
;
articular cartilage
;
diagnostic imaging
;
patella
;
stress fracture
;
surgery
;
tissue scaffold