Characterisation of the pathophysiology of neuropathy and sensory dysfunction in a mouse model of recessive dystrophic epidermolysis bullosa
Journal
Pain
ISSN
0304-3959
1872-6623
Date Issued
2022
Author(s)
Daniela Schmidt
Paula Díaz
Daniela Muñoz
Fernanda Espinoza
Alexander Nystrom
David L. Bennett
Margarita Calvo
Type
Resource Types::text::journal::journal article
URL Institutional Repository
Cite this document
Schmidt, D., Díaz, P., Muñoz, D., Espinoza, F., Nystrom, A., Fuentes, I., Ezquer, M., Bennett, D. L., & Calvo, M. (2022). Characterisation of the pathophysiology of neuropathy and sensory dysfunction in a mouse model of recessive dystrophic epidermolysis bullosa. Pain, 163(10), 2052-2060. https://doi.org/10.1097/j.pain.0000000000002599
Subjects
mouse model
;
neuropathic pain
;
neuropathy
;
rdeb
;
small-fibre neuropathy
;
animals
;
collagen type vii
;
disease models, animal
;
epidermolysis bullosa dystrophica
;
humans
;
mice
;
mutation
;
skin
;
small fiber neuropathy
;
activating transcription factor 3
;
calcitonin gene related peptide
;
collagen type 7
;
col7a1 protein, human
;
collagen type 7
;
adult
;
animal experiment
;
animal model
;
animal tissue
;
article
;
astrocyte
;
axonal injury
;
c57bl 6 mouse
;
cell population
;
controlled study
;
epidermolysis bullosa dystrophica
;
female
;
glia cell
;
heat sensitivity
;
hind paw
;
hyposensitivity (sensory dysfunction)
;
macrophage
;
male
;
mechanical hyperalgesia
;
microglia
;
morphology
;
mouse
;
mouse model
;
myelinated nerve
;
nerve ending
;
nerve fiber
;
nerve fiber c
;
nerve fiber degeneration
;
nervous system inflammation
;
neuropathy
;
nociception
;
nonhuman
;
nonmyelinated nerve
;
pain receptor
;
pathophysiology
;
place preference
;
recessive inheritance
;
satellite glial cell
;
scratching
;
sensory dysfunction
;
sensory nerve cell
;
somatosensory system
;
spinal cord nerve cell
;
spinal ganglion
;
thermal hyperalgesia
;
animal
;
complication
;
disease model
;
genetics
;
human
;
metabolism
;
mutation
;
pathology
;
skin
;
small fiber neuropathy