p27(Kip1) down-regulation as achieved by two clinically feasible means did not induce proliferation of supporting cells in the rat neonatal cochlea in vivo
Journal
Hearing Research
ISSN
0378-5955
Date Issued
2019
Author(s)
Sebastián A. Silva
Type
Resource Types::text::journal::journal article
URL Institutional Repository
Subjects
inner ear
;
labyrinth supporting cells
;
cell proliferation
;
cdkn1b protein
;
shrna
;
alsterpaullone
;
animals
;
animals, newborn
;
benzazepines
;
cell proliferation
;
cochlea
;
cyclin-dependent kinase inhibitor p27
;
down-regulation
;
indoles
;
labyrinth supporting cells
;
rats, sprague-dawley
;
rna interference
;
rna, small interfering
;
signal transduction
;
tissue culture techniques
;
alsterpaullone
;
cell marker
;
cyclin dependent kinase inhibitor 1b
;
lentivirus vector
;
short hairpin rna
;
benzazepine derivative
;
cdkn1b protein, rat
;
cyclin dependent kinase inhibitor 1b
;
indole derivative
;
small interfering rna
;
animal cell
;
animal experiment
;
article
;
cell proliferation
;
cochlea
;
cochlea duct
;
cochlea fenestra
;
cochlea injury
;
controlled study
;
corti organ
;
down regulation
;
feasibility study
;
gene expression
;
immunohistochemistry
;
in vitro study
;
in vivo study
;
newborn
;
nonhuman
;
priority journal
;
protein expression
;
protein modification
;
rat
;
reverse transcription polymerase chain reaction
;
sustentacular cell
;
animal
;
cochlea
;
drug effect
;
genetics
;
labyrinth supporting cells
;
metabolism
;
pathology
;
rna interference
;
signal transduction
;
sprague dawley rat
;
tissue culture technique