HSV-1 alters lipid metabolism and induces lipid droplet accumulation in functionally impaired mouse dendritic cells

Mónica A. Farías; Felipe A. Cancino; Areli J. Navarro; DUARTE PEÑALOZA, LUISA FERNANDA; Abel A. Soto; Eduardo I. Tognarelli; Maximiliano J. Ramm; Bárbara N. Alarcón-Zapata; José Cordero; Sergio San Martín; Cristian Agurto-Muñoz; Angello Retamal-Díaz; Claudia A. Riedel; Nelson P. Barrera; Luis Bustamante; Alexis M. Kalergis; Susan M. Bueno; Pablo A. González

doi:10.1016/j.isci.2025.112441

HSV-1 alters lipid metabolism and induces lipid droplet accumulation in functionally impaired mouse dendritic cells

Journal

iScience

ISSN

2589-0042

Date Issued

2025-05

Author(s)

Mónica A. Farías

Felipe A. Cancino

Areli J. Navarro

DUARTE PEÑALOZA, LUISA FERNANDA

Facultad de Medicina Clínica Alemana Universidad del Desarrollo

Abel A. Soto

Eduardo I. Tognarelli

Maximiliano J. Ramm

Bárbara N. Alarcón-Zapata

José Cordero

Sergio San Martín

Cristian Agurto-Muñoz

Angello Retamal-Díaz

Claudia A. Riedel

Nelson P. Barrera

Luis Bustamante

Alexis M. Kalergis

Susan M. Bueno

Pablo A. González

Type

journal-article

DOI

10.1016/j.isci.2025.112441

URL

https://investigadores.udd.cl/handle/123456789/11260

Project(s)

Role of neuropeptides in neuron and brain infection with HSV-1: Evaluation of antiviral activity and protective effects over brain damage upon infection in vivo

Dataset(s)

Dataset - HSV-1 alters lipid metabolism and induces lipid droplet accumulation in functionally impaired mouse dendritic cells

Subjects

varicella-zoster-virus

;

fatty-acid-metabolism

;

cross-presentation

;

ester synthesis

;

expression

;

cholesterol

;

infection

;

metabolomics

;

suppresses

;

activation