Intranasal mesenchymal stem cell secretome administration markedly inhibits alcohol and nicotine self-administration and blocks relapse-intake: mechanism and translational options

Journal
Stem Cell Research & Therapy
ISSN
1757-6512
Date Issued
2019
Author(s)
María Elena Quintanilla
Paola Morales
Daniela Santapau
Mario Herrera-Marschitz
Yedy Israel
Type
Resource Types::text::journal::journal article
Scopus ID
2-s2.0-85068856990
WoS ID
WOS:000475605000007
DOI
URL
URL Institutional Repository
Cite this document
Quintanilla, M. E., Ezquer, F., Morales, P., Santapau, D., Berríos-Cárcamo, P., Ezquer, M., Herrera-Marschitz, M., & Israel, Y. (2019). Intranasal mesenchymal stem cell secretome administration markedly inhibits alcohol and nicotine self-administration and blocks relapse-intake: Mechanism and translational options. Stem Cell Research & Therapy, 10(1), 205. https://doi.org/10.1186/s13287-019-1304-z
Project(s)
Subjects
ros

; 

neuroinflammation

; 

knockdown

; 

glt-1 antisense

; 

intranasal

; 

mesenchymal stem cells

; 

administration, intranasal

; 

alcohol-induced disorders, nervous system

; 

alcohols

; 

animals

; 

brain

; 

humans

; 

inflammation

; 

male

; 

mesenchymal stem cell transplantation

; 

mesenchymal stem cells

; 

nerve tissue

; 

nicotine

; 

oxidative stress

; 

rats

; 

self administration

; 

tobacco use disorder

; 

alcohol

; 

drugs used in the treatment of addiction

; 

glutamate transporter

; 

glutathione

; 

nicotine

; 

protein glt 1

; 

unclassified drug

; 

alcohol derivative

; 

nicotine

; 

adipose tissue cell

; 

alcoholism

; 

animal experiment

; 

animal model

; 

animal tissue

; 

antiinflammatory activity

; 

antioxidant activity

; 

article

; 

cellular secretion

; 

controlled study

; 

drug mechanism

; 

drug self administration

; 

female

; 

hippocampus

; 

human

; 

human cell

; 

mesenchymal stem cell

; 

nervous system inflammation

; 

nonhuman

; 

oxidative stress

; 

priority journal

; 

rat

; 

tobacco dependence

; 

animal

; 

brain

; 

drug effect

; 

drug self administration

; 

genetics

; 

inflammation

; 

intranasal drug administration

; 

male

; 

mesenchymal stem cell

; 

mesenchymal stem cell transplantation

; 

metabolism

; 

nervous tissue

; 

pathology

; 

prevention and control

; 

therapy

; 

transplantation