Clinical outcomes and bacterial characteristics of carbapenem-resistant Klebsiella pneumoniae complex among patients from different global regions (CRACKLE-2): a prospective, multicentre, cohort study
Journal
The Lancet Infectious Diseases
ISSN
1473-3099
Date Issued
2022
Author(s)
Minggui Wang
Michelle Earley
Liang Chen
Blake M Hanson
Yunsong Yu
Zhengyin Liu
Soraya Salcedo
Eric Cober
Lanjuan Li
Souha S Kanj
Hainv Gao
Karen Ordoñez
Greg Weston
Michael J Satlin
Sandra L Valderrama-Beltrán
Kalisvar Marimuthu
Martin E Stryjewski
Lauren Komarow
Courtney Luterbach
Steve H Marshall
Susan D Rudin
Claudia Manca
David L Paterson
Jinnethe Reyes
Maria V Villegas
Scott Evans
Carol Hill
Rebekka Arias
Keri Baum
Bettina C Fries
Yohei Doi
Robin Patel
Barry N Kreiswirth
Robert A Bonomo
Henry F Chambers
Vance G Fowler
Cesar A Arias
David van Duin
Lilian M Abbo
Deverick J Anderson
Rebekka Arias
Cesar A Arias
Keri Baum
Robert A Bonomo
Henry F Chambers
Liang Chen
Kean Lee Chew
Eric Cober
Heather R Cross
Partha Pratim De
Samit Desai
Sorabh Dhar
Valentina Di Castelnuovo
Lorena Diaz
AN Q Dinh
Yohei Doi
Michelle Earley
Brandon Eilertson
Beth Evans
Scott Evans
Vance G Fowler Jr
Bettina C Fries
Hainv Gao
Julia Garcia-Diaz
Omai B Garner
Kerryl Greenwood-Quaintance
Blake Hanson
Erica Herc
Carol Hill
Jesse T Jacob
Jianping Jiang
Robert C Kalayjian
Souha S Kanj
Keith S Kaye
Angela Kim
Lauren Komarow
Barry N Kreiswirth
Courtney Lauterbach
Lanjuan Li
Zhengyin Liu
Claudia Manca
Kalisvar Marimuthu
Steven H Marshall
Todd McCarty
Oon Tek Ng
Jose Millan Oñate Gutierrez
Karen Ordoñez
Robin Patel
David L Paterson
Anton Peleg
Jinnethe Reyes
Susan D Rudin
Robert A Salata
Soraya Salcedo
Michael J Satlin
Suzannah Schmidt-Malan
Nares Smitasin
Maria Spencer
Martin Stryjewski
Jiachun Su
Paul Ananth Tambyah
Sandra Valderrama
David van Duin
Maria Virginia Villegas Botero
Minggui Wang
Mary Waters
Greg Weston
Darren Wong
Glenn Wortmann
Yang Yang
Yunsong Yu
Fujie Zhang
Type
Resource Types::text::journal::journal article
URL Institutional Repository
Cite this document
Wang, M., Earley, M., Chen, L., Hanson, B. M., Yu, Y., Liu, Z., Salcedo, S., Cober, E., Li, L., Kanj, S. S., Gao, H., Munita, J. M., Ordoñez, K., Weston, G., Satlin, M. J., Valderrama-Beltrán, S. L., Marimuthu, K., Stryjewski, M. E., Komarow, L., … Zhang, F. (2022). Clinical outcomes and bacterial characteristics of carbapenem-resistant Klebsiella pneumoniae complex among patients from different global regions (CRACKLE-2): A prospective, multicentre, cohort study. The Lancet Infectious Diseases, 22(3), 401-412. https://doi.org/10.1016/S1473-3099(21)00399-6
Subjects
anti-bacterial agents
;
bacteremia
;
carbapenem-resistant enterobacteriaceae
;
carbapenems
;
cohort studies
;
humans
;
klebsiella infections
;
klebsiella pneumoniae
;
prospective studies
;
respiratory sounds
;
aerobactin
;
antibiotic agent
;
bacterial protein
;
beta lactamase
;
beta lactamase ampc
;
beta lactamase ctx m
;
beta lactamase ctx m 15
;
beta lactamase ctx m 65
;
beta lactamase kpc
;
beta lactamase kpc 2
;
beta lactamase kpc 3
;
beta lactamase ndm
;
beta lactamase ndm 1
;
beta lactamase oxa 48
;
beta lactamase oxa 48 like
;
beta lactamase shv
;
beta lactamase tem
;
carbapenemase
;
colibactin
;
extended spectrum beta lactamase
;
ompk35 protein
;
ompk36 protein
;
porin
;
rmpa2 protein
;
rmpadc protein
;
unclassified drug
;
yersiniabactin
;
antiinfective agent
;
carbapenem derivative
;
acutely ill patient
;
adult
;
aged
;
all cause mortality
;
antibiotic therapy
;
argentina
;
article
;
australia
;
bacteremia
;
bacterial colonization
;
bacterial strain
;
bacterial virulence
;
bacterium culture
;
bacterium isolate
;
carbapenem resistant klebsiella pneumoniae
;
charlson comorbidity index
;
chile
;
china
;
chronic kidney failure
;
clinical feature
;
clinical outcome
;
cohort analysis
;
colombia
;
controlled study
;
dementia
;
diabetes mellitus
;
female
;
gene mutation
;
genetic variation
;
hospital patient
;
hospital readmission
;
human
;
klebsiella pneumoniae
;
klebsiella pneumoniae infection
;
klebsiella pneumoniae sensu stricto
;
klebsiella quasipneumoniae subsp quasipneumoniae
;
klebsiella quasipneumoniae subsp similipneumoniae
;
klebsiella variicola subsp variicola
;
lebanon
;
length of stay
;
major clinical study
;
male
;
multicenter study
;
multilocus sequence typing
;
nonhuman
;
prospective study
;
singapore
;
single nucleotide polymorphism
;
south america
;
united states
;
urinary tract infection
;
urine culture
;
whole genome sequencing
;
abnormal respiratory sound
;
bacteremia
;
carbapenem-resistant enterobacteriaceae
;
clinical trial
;
genetics
;
klebsiella infection
;
microbiology