Changes in the SNAr reaction mechanism brought about by preferential solvation
Journal
RSC Advances
ISSN
2046-2069
Date Issued
2015
Author(s)
Jazmín Alarcón-Espósito
Ricardo A. Tapia
Renato Contreras
Type
Resource Types::text::journal::journal article
URL Institutional Repository
Abstract
<p>For model S<sub>N</sub>Ar reactions in mixtures of acetonitrile and water, we found preferential solvation in favor of the aqueous phase.</p>
Subjects
nucleophilic-substitution reactions
;
binary solvent mixtures
;
ionic liquids
;
secondary-amines
;
aromatic-substitution
;
acetonitrile
;
benzenesulfonates
;
regioselectivity
;
aminolysis
;
parameters