First-Ever Stroke and Transient Ischemic Attack Incidence and 30-Day Case-Fatality Rates in a Population-Based Study in Argentina
Journal
Stroke
ISSN
0039-2499
1524-4628
Date Issued
2016
Author(s)
M. Cecilia Bahit
Mariano L. Coppola
Patricia M. Riccio
Lauren E. Cipriano
Gregory A. Roth
Renato D. Lopes
Valery L. Feigin
Brenda Borrego Guerrero
Maximiliano De Martino
Alejandro Díaz
Daniel Ferrante
Fernando Funaro
M. Laura Lewin
Daniel H. López
Patricia Macarrone
Rafael Marciello
Diego Marino
Cecilia Martens
Paula Martínez
Guillermo Odriozola
Alejandro A. Rabinstein
Gustavo Saposnik
Damián Silva
Ramón Suasnabar
Thomas Truelsen
Araceli Uzcudun
Carlos A. Viviani
Luciano A. Sposato
Type
Resource Types::text::journal::journal article
URL Institutional Repository
Abstract
<jats:sec>
<jats:title>Background and Purpose—</jats:title>
<jats:p>Epidemiological data about stroke are scarce in low- and middle-income Latin-American countries. We investigated annual incidence of first-ever stroke and transient ischemic attack (TIA) and 30-day case-fatality rates in a population-based setting in Tandil, Argentina.</jats:p>
</jats:sec>
<jats:sec>
<jats:title>Methods—</jats:title>
<jats:p>We prospectively identified all first-ever stroke and TIA cases from overlapping sources between January 5, 2013, and April 30, 2015, in Tandil, Argentina. We calculated crude and standardized incidence rates. We estimated 30-day case-fatality rates.</jats:p>
</jats:sec>
<jats:sec>
<jats:title>Results—</jats:title>
<jats:p>We identified 334 first-ever strokes and 108 TIAs. Age-standardized incidence rate per 100 000 for Segi’s World population was 76.5 (95% confidence interval [CI], 67.8–85.9) for first-ever stroke and 25.1 (95% CI, 20.2–30.7) for first-ever TIA, 56.1 (95% CI, 48.8–64.2) for ischemic stroke, 13.5 (95% CI, 9.9–17.9) for intracerebral hemorrhage, and 4.9 (95% CI, 2.7–8.1) for subarachnoid hemorrhage. Stroke incidence was slightly higher for men (87.8; 95% CI, 74.6–102.6) than for women (73.2; 95% CI, 61.7–86.1) when standardized for the Argentinean population. Thirty-day case-fatality rate was 14.7% (95% CI, 10.8–19.5) for ischemic stroke, 24.1% (95% CI, 14.2–36.6) for intracerebral hemorrhage, and 1.9% (95% CI, 0.4–5.8) for TIA.</jats:p>
</jats:sec>
<jats:sec>
<jats:title>Conclusions—</jats:title>
<jats:p>This study provides the first prospective population-based stroke and TIA incidence and case-fatality estimate in Argentina. First-ever stroke incidence was lower than that reported in previous Latin-American studies, but first-ever TIA incidence was higher. Thirty-day case-fatality rates were similar to those of other population-based Latin-American studies.</jats:p>
</jats:sec>
<jats:title>Background and Purpose—</jats:title>
<jats:p>Epidemiological data about stroke are scarce in low- and middle-income Latin-American countries. We investigated annual incidence of first-ever stroke and transient ischemic attack (TIA) and 30-day case-fatality rates in a population-based setting in Tandil, Argentina.</jats:p>
</jats:sec>
<jats:sec>
<jats:title>Methods—</jats:title>
<jats:p>We prospectively identified all first-ever stroke and TIA cases from overlapping sources between January 5, 2013, and April 30, 2015, in Tandil, Argentina. We calculated crude and standardized incidence rates. We estimated 30-day case-fatality rates.</jats:p>
</jats:sec>
<jats:sec>
<jats:title>Results—</jats:title>
<jats:p>We identified 334 first-ever strokes and 108 TIAs. Age-standardized incidence rate per 100 000 for Segi’s World population was 76.5 (95% confidence interval [CI], 67.8–85.9) for first-ever stroke and 25.1 (95% CI, 20.2–30.7) for first-ever TIA, 56.1 (95% CI, 48.8–64.2) for ischemic stroke, 13.5 (95% CI, 9.9–17.9) for intracerebral hemorrhage, and 4.9 (95% CI, 2.7–8.1) for subarachnoid hemorrhage. Stroke incidence was slightly higher for men (87.8; 95% CI, 74.6–102.6) than for women (73.2; 95% CI, 61.7–86.1) when standardized for the Argentinean population. Thirty-day case-fatality rate was 14.7% (95% CI, 10.8–19.5) for ischemic stroke, 24.1% (95% CI, 14.2–36.6) for intracerebral hemorrhage, and 1.9% (95% CI, 0.4–5.8) for TIA.</jats:p>
</jats:sec>
<jats:sec>
<jats:title>Conclusions—</jats:title>
<jats:p>This study provides the first prospective population-based stroke and TIA incidence and case-fatality estimate in Argentina. First-ever stroke incidence was lower than that reported in previous Latin-American studies, but first-ever TIA incidence was higher. Thirty-day case-fatality rates were similar to those of other population-based Latin-American studies.</jats:p>
</jats:sec>
Subjects
death
;
incidence
;
population
;
stroke