The hidden economic and disease burden of early-life antibiotics and psychotropic medication in mothers and children: a large retrospective cohort study

Project Title

Partner Organisations

Pontificia Universidad Católica de Chile

Internal ID

1242022

Principal Investigator

EDUARDO A UNDURRAGA

Type

applied research

Status

VIGENTE

Start Date

April 1, 2024

End Date

April 1, 2028

Investigators

MUNITA SEPULVEDA, JOSE MANUEL

Organisations

Facultad de Medicina Clínica Alemana Universidad del Desarrollo

Fields of Science and Technology (OECD)

Medical and Health sciences

Publications

Now showing 1 - 3 of 3

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Cost-effectiveness of screening, decolonisation and isolation strategies for carbapenem-resistant Enterobacterales and methicillin-resistant Staphylococcus aureus infections in hospitals: a sex-stratified mathematical modelling study
(Elsevier BV, 2025-03)
Kasim Allel
;
Patricia Garcia
;
Anne Peters
;
MUNITA SEPULVEDA, JOSE MANUEL
;
Eduardo A. Undurraga
2
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Excess burden of antibiotic-resistant bloodstream infections: evidence from a multicentre retrospective cohort study in Chile, 2018–2022
(2024)
Kasim Allel
;
Anne Peters
;
Hassan Haghparast-Bidgoli
;
Maria Spencer-Sandino
;
Jose Conejeros
Scopus© Citations 2 4
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Prevalence and Distribution of Salmonella in Water Bodies in South America: A Systematic Review
(MDPI AG, 2025-02-22)
Makarena Sofia Gonzalez Reyes
;
Rayana Santos Araujo Palharini
;
Felipe Ferreira Monteiro
;
Salvador Ayala
;
Eduardo A. Undurraga
The presence of Salmonella in rivers, lakes, or beaches in South America represents a challenge to public health and aquatic ecosystems. This review explores the distribution, prevalence, and the main factors contributing to the survival and spread of Salmonella, including wastewater discharge, agricultural runoff, and climatic variables such as high temperatures and precipitation. These factors also facilitate the distribution of multidrug-resistant strains in water. The review is based on bibliographic searches in various databases, focusing on Salmonella species, South American countries, and types of water bodies. Predominant serovars include S. Enteritidis and S. Typhimurium, with S. Typhi and S. Panama frequently detected in Chile, S. Enteritidis in Argentina, and S. Typhimurium in Brazil. Less common serovars, including S. Dublin and S. Paratyphi B, were identified, along with subspecies such as diarizonae and houtenae. These findings highlight the role of environmental, physicochemical, and anthropogenic factors influencing Salmonella dynamics. The review identifies research gaps, advocating for further studies to better understand the interactions between Salmonella, climate change, and human activity. Strengthening surveillance and mitigation strategies is crucial to protect water resources and public health in South America.
Scopus© Citations 3 1

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