FAJRE WIPE, XIMENA ELIZABETH
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FAJRE WIPE, XIMENA ELIZABETH
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xfajre@udd.cl

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Xantogranuloma juvenil gigante y ulcerado: una presentación atípica en lactantes

2023 , Sofía Guelfand Warnken , Ximena Fajre Wipe , Claudia Suarez Aldunate , Rosario Aguero Ureta , CASTRO MENDEZ, ALEX

El xantogranuloma juvenil (XGJ) gigante es una variante infrecuente de XGJ, se caracteriza por una lesión mayor a 2 cm de diámetro. Generalmente se presenta como placa y rara vez, como nódulo ulcerado. Objetivo: Reportar dos casos de XGJ de presentación atípica, destacando la importancia de considerarlos dentro del diagnóstico diferencial de tumores ulcerados de gran tamaño en lactantes. Casos Clínicos: Caso 1: Lactante masculino sano, consultó por nódulo inguinal eritematoso indurado de 2,6 cm con ulceración central, presente desde los 2 meses de edad, de crecimiento rápido y progresivo. Se realizó biopsia incisional cuya histología fue compatible con XGJ. Se descartó compromiso oftalmológico. Se realizó extirpación quirúrgica excisional por su impacto funcional y preocupación de los cuidadores. Evolucionó favorablemente sin recidiva local a 4 años de seguimiento. Caso 2: Lactante masculino sano consultó por nódulo escapular derecho de 2,4 cm, de consistencia firme, con costra central, presente desde el mes de vida, de crecimiento rápido y progresivo. El estudio histológico incisional fue compatible con XGJ. Se descartó compromiso oftalmológico y en 18 meses de seguimiento clínico seriado, presentó disminución progresiva del tamaño de la lesión. Conclusiones: Los casos presentados destacan la importancia de considerar el XGJ dentro del diagnóstico diferencial de tumores cutáneos ulcerados de gran tamaño en lactantes. Frente a presentaciones clínicas atípicas, el estudio histológico ayuda a confirmar el diagnóstico. Dado el pronóstico favorable, se aconseja el seguimiento clínico periódico y, en casos excepcionales, se puede optar por tratamientos quirúrgicos o ablativos. 

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Multifocal capillary malformation with segmental distribution and central atrophy: A case in a 12‐year‐old girl

2021 , ROLLAN MARZOLO, MARIA PAZ , FAJRE WIPE, XIMENA ELIZABETH , Consuelo Giordano , WHITTLE, CAROLINA , CASTRO MENDEZ, ALEX

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Herniated superficial lipomas in gluteal and thigh support areas: a special clinical ultrasound presentation

2022 , WHITTLE, CAROLINA , FAJRE WIPE, XIMENA ELIZABETH , Catalina Silva , CASTRO MENDEZ, ALEX

Background Lipomas are the most frequent benign tumor. They have been described as soft, well-defined, slow-growing palpable masses, and classified as deep or superficial. Purpose To present the clinical and ultrasound findings of herniated superficial subcutaneous lipoma (HSL), located in pressure/support areas, not previously described. Material and Methods A seven-year retrospective review was performed. Patients with a preoperative high-resolution ultrasound (HRUS) diagnosis of HSL archived in the computational system and histological study information were selected. Results A total of 37 patients (mean age = 46 years) were recruited. The clinical diagnoses were “lipoma” or “suspected lipoma” in just 46% of the cases. This was three times more frequent in women. Tumors were located mainly in the gluteal (38%) and proximal thigh areas (35%). Clinically, all patients showed small, soft, rounded skin nodules. On HRUS, they appear as lipomatous tumors that protruded, compressed, and thinned the covering dermal layer. The subcutaneous portion was bigger than the herniated part, with an iceberg image. Conclusion HSL in support areas have a special clinical ultrasound presentation, not previously described. It is important to recognize them for a proper diagnosis and treatment, especially because they clinically may present as small superficial lesions; however, they are associated with a larger subcutaneous portion (iceberg image). It is probable that an estrogen influence on the adipose tissue can be suspected because of the female predominance.

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Skin biopsy for the diagnosis of cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy: A report of two cases

2020 , MARIA JOSE PEREIRA ORELLANA , KHANTY ANTONIETA MARYLAS LOYOLA AVILA , FAJRE WIPE, XIMENA ELIZABETH , DIEGO ANDRES ROCHA JIMENEZ , PABLO JOSE BRINCK GIUGLIANO , MARCELA SCHULTZ HARAMOTO , GONZALO HEVIA VALDES

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Ultrasonographic Spectrum of Cutaneous Cysts with Stratified Squamous Epithelium in Pediatric Dermatology

2022 , WHITTLE, CAROLINA , Catalina Silva‐Hirschberg , Khanty Loyola , FAJRE WIPE, XIMENA ELIZABETH , Ana Andrews

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Dermatoscopy of a Primary Dermal Melanoma

2009 , CABRERA MORAGA, RAUL ALEJANDRO , Constanza Pulgar , Francisca Daza , CASTRO MENDEZ, ALEX , Víctor G Prieto , Juanita Benedetto , FAJRE WIPE, XIMENA ELIZABETH

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Laugier-Hunziker syndrome in a patient with Sjogren's syndrome. Report of one case

2016 , FAJRE WIPE, XIMENA ELIZABETH , María Aspillga , María McNab , Verónica Sanhueza , Juana Benedetto , Jorge Navarrete

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Subungual Exostosis: High-Resolution Ultrasound Findings

2019 , WHITTLE, CAROLINA , Javiera Aguirre , Veronica Catalán , Fabiola Vargas , FAJRE WIPE, XIMENA ELIZABETH

Subungual exostosis is a rare solitary benign osteocartilaginous tumor that arises from the tuft of the distal phalanx beneath the nail. Because of its multiple clinical presentations, it is commonly underdiagnosed, resulting in delayed diagnosis and inadequate treatment. This report provides results from a 6-year retrospective study. All patients with a sonographic diagnosis of subungual exostosis confirmed surgically were selected. The data came from a series of 19 patient cases. Only 15.7% were clinically suspected. The median age was 21 years, and 63% were females. The sonographic findings were nail dystrophy, distal onycholysis, abnormal nail incurvation, subungual space enlargement, and the presence of hyperechogenic subungual image with acoustic shadowing that continued until the phalanx surface. Sonography provides an excellent diagnostic method for subungual exostosis, with findings that are pathognomonic.

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Lamotrigine-induced Sweet syndrome: Possible new drug association

2020 , Gabriel Neely , FAJRE WIPE, XIMENA ELIZABETH , CABRERA MORAGA, RAUL ALEJANDRO , CASTRO MENDEZ, ALEX

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