DIAZ TAPIA, VIOLETA DEL CARMEN
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DIAZ TAPIA, VIOLETA DEL CARMEN
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vdiaz@udd.cl

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Frequency and Determinants of Poststroke Cognitive Impairment at Three and Twelve Months in Chile

2010 , Carolina Delgado , Archibaldo Donoso , Patricia Orellana , Carolina Vásquez , DIAZ TAPIA, VIOLETA DEL CARMEN , BEHRENS PELLEGRINO, MARIA ISABEL

A higher risk of poststroke cognitive impairment (CI) has been reported in Hispanics in a US cohort but has not been systematically studied in Latin America. <i>Objectives:</i> Our purpose was to investigate the frequencies and determinants of poststroke CI in the hispano-mestizo population of Santiago, Chile. <i>Methods:</i> A prospective study of hospitalized patients aged >60 years admitted with an ischemic or hemorrhagic stroke was conducted. The cognitive status was determined at 3 and 12 months after the stroke by informant questionnaires, neuropsychological testing and clinical diagnosis. Cardiovascular risk factors, brain imaging and stroke features were analyzed using regression models to establish determinants for poststroke CI. <i>Results:</i> A total of 164 patients (mean age = 72 ± 7.5 years) were recruited. Out of 122 patients (74%) evaluated at 3 months, 81 (66%) had CI. Out of 101 patients (62%) evaluated at 12 months, 39 (39%) had CI no dementia, and 22 (22%) were demented. The new-onset dementia frequency at 1 year was 16%. Independent determinants for dementia were higher functional impairment at hospital egress (OR = 4.0), left-hemisphere large-vessel infarction (OR = 6.9) and a larger amount of white matter changes (OR = 1.3). <i>Conclusions:</i> In this first study on poststroke CI in Latin America, the frequencies and determinants of poststroke CI were similar to those in other cohorts of different ethnic origin.

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Validity of the NIHSS in predicting arterial occlusion in cerebral infarction is time-dependent

2010 , V. V. Olavarria , DELGADO BECERRA, OROZIMBA IRIS , HOPPE WIEGERING, ARNOLD JOHANNES GOTTLIEB , BRUNSER, ALEJANDRO , D. Carcamo , DIAZ TAPIA, VIOLETA DEL CARMEN , LAVADOS GERMAIN, PABLO MANUEL

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Cryptococcus bacillisporus (VGIII) Meningoencephalitis Acquired in Santa Cruz, Bolivia

2021 , THOMPSON MOYA, LUIS ADALBERTO , PORTE TORRE, LORENA ISABEL , DIAZ TAPIA, VIOLETA DEL CARMEN , María Cristina Díaz , Sebastián Solar , Pablo Valenzuela , Nicole Norley , Yumai Pires , Fernando Carreño , Sergio Valenzuela , Rukmane Shabani , Volker Rickerts , WEITZEL, THOMAS

We describe a case of chronic meningoencephalitis with hydrocephalus caused by Cryptococcus bacillisporus (VGIII) in an immunocompetent patient from Santa Cruz, Bolivia. This first report of a member of the Cryptococcus gattii species complex from Bolivia suggests that C. bacillisporus (VGIII) is present in this tropical region of the country and complements our epidemiological and clinical knowledge of this group of emerging fungal pathogens in South America.

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Incidence of multiple sclerosis in Chile. A hospital registry study

2011 , DIAZ TAPIA, VIOLETA DEL CARMEN , J. Barahona , J. Antinao , R. Quezada , DELGADO BECERRA, OROZIMBA IRIS , C. Silva , R. J. Guiloff

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Seasonal trend of cervical artery dissection in a Chilean cohort

2019 , RECULE GONZALEZ, FRANCISCA , MAZZON AGURTO, ENRICO , DIAZ TAPIA, VIOLETA DEL CARMEN , Rocha, Diego , BRUNSER RABOVICH, ALEJANDRO MICHEL , De La Barra, Camila , Zuniga, Paulo , Dominga Garcia, Maria , Gabriel Cavada , MUÑOZ VENTURELLI, PAULA ANDREA , Zeballos, Shirley , Charaf, Yusef

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Association between spontaneous internal carotid artery dissection and perivascular adipose tissue attenuation on computed tomography angiography

2023 , Kevin Cheng , Andrew Lin , STECHER GUZMAN, XIMENA PATRICIA , Tomas Bernstein , Paulo Zuñiga , Gonzalo Martinez , BRUNSER, ALEJANDRO , DIAZ TAPIA, VIOLETA DEL CARMEN , MAZZON AGURTO, ENRICO , William Cameron , Stephen J Nicholls , Sanjay Patel , Damini Dey , Dennis TL Wong , MUÑOZ VENTURELLI, PAULA ANDREA

Background: Spontaneous cervical artery dissection (sCAD) is a leading cause of ischemic stroke in young patients. Studies using high-resolution magnetic resonance imaging and positron emission tomography have suggested vessel wall inflammation to be a pathogenic factor in sCAD. Computed tomography (CT) attenuation of perivascular adipose tissue (PVAT) is an established non-invasive imaging biomarker of inflammation in coronary arteries, with higher attenuation values reflecting a greater degree of vascular inflammation. Objectives: We evaluate the CT attenuation of PVAT surrounding the internal carotid artery (PVATcarotid) with and without spontaneous dissection. Methods: Single-center prospective observational study of 56 consecutive patients with CT-verified spontaneous dissection of the internal carotid artery (ICA). Of these patients, six underwent follow-up computed tomography angiography (CTA). Twenty-two patients who underwent CTA for acute neurological symptoms but did not have dissection formed the control group. Using semi-automated research software, PVATcarotid was measured as the mean Hounsfield unit (HU) attenuation of adipose tissue within a defined volume of interest surrounding the ICA. Results: PVATcarotid was significantly higher around dissected ICA compared with non-dissected contralateral ICA in the same patients (−58.7 ± 10.2 vs −68.9 ± 8.1 HU, p < 0.0001) and ICA of patients without dissection (−58.7 ± 10.2 vs −69.3 ± 9.3 HU, p < 0.0001). After a median follow-up of 89 days, there was a significant reduction in PVATcarotid around dissected ICA (−57.5 ± 13.4 to −74.3 ± 10.5 HU, p < 0.05), while no change was observed around non-dissected contralateral ICA (−71.0 ± 4.4 to −74.1 ± 4.1 HU, p = 0.19). ICA dissection was an independent predictor of PVATcarotid following multivariable adjustment for age and the presence of ICA occlusion. Conclusion: PVATcarotid is elevated in the presence of sCAD and may decrease following the acute event.

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High-Dose Intravenous Methylprednisolone for Hantavirus Cardiopulmonary Syndrome in Chile: A Double-Blind, Randomized Controlled Clinical Trial

2013 , Pablo A. Vial , Francisca Valdivieso , Marcela Ferres , Raul Riquelme , M. Luisa Rioseco , Mario Calvo , Constanza Castillo , Ricardo Díaz , Luis Scholz , Analia Cuiza , Edith Belmar , Carla Hernandez , Jessica Martinez , Sang-Joon Lee , Gregory J. Mertz , Juan Abarca , Vinko Tomicic , M. Eugenia Aracena , Ana Maria Rehbein , Soledad Velásquez , Victoria Lavin , Felipe Garrido , Paula Godoy , Constanza Martinez , Juan Carlos Chamorro , Jorge Contreras , Jury Hernandez , Marcelo Pino , Paola Villegas , Viviana Zapata , Marisol León , Ivonne Vega , Irisol Otarola , Carlos Ortega , Elizabeth Daube , Doris Huecha , Alda Neira , Ines Ruiz , M. Antonieta Nuñez , Luz Monsalve , Henriette Chabouty , Lorena Riquelme , Samia Palma , Raul Bustos , Ruben Miranda , Jovita Mardones , Nora Hernandez , Yasna Betancur , Ligia Sanhueza , Jaime Inostroza , Solange Donoso , Maritza Navarrete , Lily Acuña , Paulina Manriquez , Fabiola Castillo , Paola Unzueta , Teresa Aguilera , Carola Osorio , Veronica Yobanolo , Jorge Mardones , Sandra Aranda , Soledad Carvajal , Moisés Sandoval , Soraya Daza , Felipe Vargas , Violeta Diaz , Mauricio Riquelme , Miriam Muñoz , Andrea Carriel , Paola Lanino , Susana Hernandez , Patricia Schumacher , Lia Yañez , Claudia Marco , Mildred Ehrenfeld , Iris Delgado , Susana Rios , Cecilia Vial , Edward Bedrick

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Cervical Artery Dissection in Postpartum Women after Cesarean and Vaginal Delivery

2022 , Francisca Urrutia , MAZZON AGURTO, ENRICO , BRUNSER, ALEJANDRO , DIAZ TAPIA, VIOLETA DEL CARMEN , CALDERON GIADROSIC, JUAN FRANCISCO , STECHER GUZMAN, XIMENA PATRICIA , Tomas Bernstein , Paulo Zuñiga , SCHILLING REDLICH, ANDREA INGRID , MUÑOZ VENTURELLI, PAULA

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Transcranial Doppler in a Hispanic–Mestizo population with neurological diseases: a study of sonographic window and its determinants

2012 , BRUNSER, ALEJANDRO , SILVA FUENTE ALBA, CLAUDIO SERGIO , Cárcamo, Daniel , MUÑOZ VENTURELLI, PAULA , OLAVARRIA IANISZEWSKY, VERONICA VIVIANA , Abarca, Juan , HOPPE WIEGERING, ARNOLD JOHANNES GOTTLIEB , DIAZ TAPIA, VIOLETA DEL CARMEN

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Transcranial Doppler as a Predictor of Ischemic Events in Vertebral Artery Dissection

2020 , BRUNSER, ALEJANDRO , LAVADOS GERMAIN, PABLO MANUEL , Gabriel Cavada , MUÑOZ VENTURELLI, PAULA ANDREA , OLAVARRIA IANISZEWSKY, VERONICA VIVIANA , NAVIA GONZALEZ, VICTOR HUGO , Eloy Mansilla , DIAZ TAPIA, VIOLETA DEL CARMEN

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