Research Output

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Now showing 1 - 10 of 29
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Tinea faciei por Trichophyton violaceum: primer caso alóctono reportado en Chile

2022 , CABRERA MORAGA, RAUL ALEJANDRO , Sofía Guelfand , Macarena Stevenson , Marie-Chantal Caussade , Daniel Velázquez , Eduardo Álvarez

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Dermatoscopy of an Angiomatoid Spitz Nevus

2011 , CABRERA MORAGA, RAUL ALEJANDRO , Francisca Daza , Denis Tom , Victor G Prieto , CASTRO MENDEZ, ALEX

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New Markers for Cardiovascular Disease in Psoriatic Patients: Preliminary Study on Monocyte Phenotype, ADAMTS7, and mTOR Activity

2023 , Khanty Loyola , Claudio Karsulovic , CABRERA MORAGA, RAUL ALEJANDRO , Claudio Perez , HOJMAN CANO, LIA PAULA

Psoriasis is a skin disease with occasional involvement of non-cutaneous territories. Beyond the usual, cardiovascular events are more frequent in these patients and correlate only partially with disease activity, suggesting the presence of other unknown factors. We selected ten psoriatic patients without treatment in the last year and matched them for age and gender with eleven healthy subjects. Ficoll-extracted mononuclear cells were analyzed with flow cytometry for monocyte surface phenotype markers, intracellular NFκB/inflammasome-dependent interleukins, and chemotaxis receptor CXCR3. Using ELISA, patient serum was evaluated for ADAMTS7 and CXCL10. Inflammatory M1 monocytes showed higher levels of IL-1β and IL-6 in psoriatic patients. M2 monocytes also showed higher levels of intracellular inflammatory cytokines. Nevertheless, IL-6 values were higher compared to other monocytes and IL-1β. The mTORC activation markers ADAMTS7 and S6Rp were higher in psoriatic patients than in healthy controls. In psoriatic patients, serum levels of ADAMTS7 were elevated, and M2 monocytes showed a distinct inflammatory response with higher relative levels of NFκB-dependent IL-6 and less activity of the CXCR3–CXCL10 chemotactic pathway. These data suggest pathways with potential markers for prediction and early detection of cardiovascular risk in psoriatic patients.

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Do not forget to check the scalp in systemic light-chain amyloidosis

2021 , LARRONDO, JORGE , Marianne Gosch , Camila Peña , CABRERA MORAGA, RAUL ALEJANDRO , Cecilia Jeraldo , CASTRO MENDEZ, ALEX , Amy J. McMichael

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Tungiasis: eggs seen with dermoscopy

2008 , CABRERA MORAGA, RAUL ALEJANDRO , Daza, Francisca

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Dermoscopy in the diagnosis of tungiasis

2009 , CABRERA MORAGA, RAUL ALEJANDRO , Daza, Francisca

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Predictive Model for Response Rate to Narrowband Ultraviolet B Phototherapy in Vitiligo: A Retrospective Cohort Study of 579 Patients

2018 , CABRERA MORAGA, RAUL ALEJANDRO , L Hojman , F Recule , R Sepulveda , I Delgado , DELGADO BECERRA, OROZIMBA IRIS

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Unusual Clinical Presentations of Malignant Melanoma: A Review of Clinical and Histologic Features with Special Emphasis on Dermatoscopic Findings

2018 , CABRERA MORAGA, RAUL ALEJANDRO , Francisca Recule

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Cromhidrosis ecrina por hiperbilirrubinemia secundaria a terapia antirretroviral

2017 , Jaime Pérez W. , CABRERA MORAGA, RAUL ALEJANDRO , CASTRO MENDEZ, ALEX , Fernando Pérez , Agustina Romanello , Máximo Venegas , Viviana García

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Dermatoscopy of a Primary Dermal Melanoma

2009 , CABRERA MORAGA, RAUL ALEJANDRO , Constanza Pulgar , Francisca Daza , CASTRO MENDEZ, ALEX , Víctor G Prieto , Juanita Benedetto , FAJRE WIPE, XIMENA ELIZABETH