DELGADO BECERRA, OROZIMBA IRIS
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DELGADO BECERRA, OROZIMBA IRIS
Main Affiliation
Email
idelgado@udd.cl
ORCID
Scopus Author ID
15051503300

Research Output

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Continuous EPO receptor activator therapy of anemia in children under peritoneal dialysis

2011 , Francisco Cano , Claudia Alarcon , Marta Azocar , Carolina Lizama , Ana Maria Lillo , Angela Delucchi , Mariluz Gonzalez , Patricia Arellano , DELGADO BECERRA, OROZIMBA IRIS , Maria Teresa Droguett

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FREE WATER TRANSPORT AND ITS ASSOCIATION WITH CARDIOVASCULAR STATUS IN CHILDREN ON PERITONEAL DIALYSIS

2019 , Lilian Bolte , Maria Jose Ibacache , Francisco Cano , DELGADO BECERRA, OROZIMBA IRIS

BackgroundVolume overload is one of the most important factors associated with left ventricular hypertrophy (LVH) and cardiovascular disease in chronic peritoneal dialysis (PD) patients. MiniPET is a reliable tool to evaluate free water transport (FWT). In a clinical setting, the significance of FWT has not been evaluated in terms of outcome in children on PD. The objective was to define a FWT value of clinical significance in children on PD, fixing its relationship to left ventricular mass index (LVMI) as a well-known outcome parameter.MethodsMiniPET was performed with 3.86% glucose, 1-h long, to measure FWT in PD patients > 6 years old. An echocardiogram (ECG) was performed within 2 months of the MiniPET. Left ventricular hypertrophy was defined as LVMI ≥ 38.6 g/height2.7(95th percentile). Receiver operating characteristic curve (ROC) analysis was used to determine the cut-off value of FWT searching the highest sensitivity and specificity to differentiate patients with normal/abnormal LVMI. A p < 0.05 was considered significant.ResultsForty-six studies were performed on 32 patients, 16 males; mean age 11.59 ± 3.07 years. Mean normalized FWT (nFWT) was 144.4 ± 84.8 mL/m2, corresponding to 46.7% of total ultrafiltration. Mean LVMI was 42 ± 11.3 g/m2.7with a negative correlation to nFWT ( p < 0.01). Eighteen out of 32 patients had LVH. The ROC analysis (nFWT vs LVMI) showed an area under the curve of 0.71 (95% confidence interval [CI], 0.53 – 0.89; p = 0.04), allowing a cut-off nFWT value of 110 mL/m2to be defined, dividing the population into 2 groups of patients according to the LVMI cut-off value of 38,6 g/m2.7.ConclusionsThe nFWT showed an inverse correlation to LVMI. A nFWT value < 110 mL/m2was significantly associated with LVH. The negative relationship observed between nFWT and LVMI, and the cut-off level for nFWT according to the 95th percentile of LVMI, suggest that the regular evaluation of nFWT could become a useful tool in assessing the capacity of PD treatment to keep patients’ volume status under control, avoiding cardiovascular impairment.

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Evolución de las licencias por enfermedad grave del niño(a) menor de un año 2004-2008: certezas e interrogantes

2012 , DELGADO BECERRA, OROZIMBA IRIS , Florencia Prieto U , HIRMAS ADAUY, MACARENA SOLEDAD

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Instrumentos para medir la capacidad funcional intrínseca y la fragilidad de personas mayores en la Atención Primaria en Chile

2022 , Marco Cornejo-Ovalle , DELGADO BECERRA, OROZIMBA IRIS , XAVIERA ANTONIA MOLINA AVENDAÑO , MASFERRER RIQUELME, DOMINIQUE ANDREA

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Los autores aludidos ofrecieron la siguiente réplica

2016 , REPETTO LISBOA, MARIA GABRIELA , BENAVIDES GONZALEZ, FELIPE ORLANDO , DELGADO BECERRA, OROZIMBA IRIS

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Predictive Models for Pulmonary Function Changes After Radiotherapy for Breast Cancer and Lymphoma

2012 , Beatriz Sánchez-Nieto , Karen C. Goset , CAVIEDES SOTO, IVAN RICARDO , DELGADO BECERRA, OROZIMBA IRIS , Andrés Córdova

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Experience with capsule endoscopy diagnostic tool for the small intestine

2010-03 , DELGADO BECERRA, OROZIMBA IRIS , Sanhueza, Edgar , Ibáñez, Patricio , Araya, Raúl , Quezada, Soledad , Jadue, Liliana , Navarrete, Claudio

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Compliance with the smoking ban in enclosed, semiopen and open areas of workplaces and public places in Chile

2020 , PERUGA URREA, ARMANDO , Xaviera Molina , DELGADO BECERRA, OROZIMBA IRIS , MATUTE WILLEMSEM, MARIA ISABEL , OLEA NORMANDIN, ANDREA MARIA , HIRMAS ADAUY, MACARENA SOLEDAD , GONZALEZ WIEDMAIER, CLAUDIA MARTA , AGUILERA SANHUEZA, XIMENA PAZ

ObjectiveTo assess the national level of compliance with the Chilean comprehensive smoke-free legislation by observing healthcare facilities, education centres, government offices, hospitality venues and private workplaces, by type of area within workplaces and public places: enclosed, semiopen and open.MethodologyIn this cross-sectional observational study, we studied a national representative sample of 3253 venues obtained through a two-stage cluster sampling design. First, 57 municipalities were randomly selected, proportionally to the total number of venues of interest. Second, within each selected municipality, a maximum of 12 venues of each sector was selected systematically from a list of existing sites. We determined the non-compliance level by estimating the percentage of the visited venues where smoking was observed or suspected in banned areas of the premises.ResultsSmoking or suspicion thereof was not observed in any enclosed area of any establishment. However, smoking violations were observed in semiopen areas ranging from less than 0.5% of schools and healthcare centres to around 10% of hospitality venues or 23.0% of higher education centres. Smoking violations were also observed in outdoor areas of 6.7% and 1.6% of the health centres and schools, respectively.DiscussionThe stark contrast in compliance with the smoking ban between the enclosed areas and the semiopen areas may be a consequence of the complex definition of semiopen areas in the regulations. The study also reflects the need to improve the overall enforcement of the smoke-free law, particularly in universities and hospitality venues.

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Monitoring and Evaluating Progress towards Universal Health Coverage in Chile

2014 , AGUILERA SANHUEZA, XIMENA PAZ , Carla Castillo-Laborde , Manuel Nájera-De Ferrari , Ciro Ibañez , DELGADO BECERRA, OROZIMBA IRIS

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Comparative evaluation of survival prognosis using MELD or Child-Pugh scores in patients with liver cirrhosis in Chile

2017 , Edgar Sanhueza , Jorge Contreras , Rodrigo Zapata , Matías Sanhueza , Fabián Elgueta , Constanza López , Sigrid Jerez , Verónica Jerez , DELGADO BECERRA, OROZIMBA IRIS

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