LEPPE ZAMORA, JAIME ESTEBAN
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LEPPE ZAMORA, JAIME ESTEBAN
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jleppe@udd.cl
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56875386300

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Uninterrupted Actigraphy Recording to Quantify Physical Activity and Sedentary Behaviors in Mechanically Ventilated Adults

2022 , Felipe González-Seguel , Agustín Camus-Molina , Macarena Leiva-Corvalán , Kirby P. Mayer , Jaime Leppe

Purpose: We evaluated the feasibility of quantification of physical activity (PA) and sedentary behaviors (SB) using actigraphy during an entire intensive care unit (ICU) length of stay. Methods: A prospective study was performed in a 12-bed ICU. Triaxial accelerometers were fitted on the right ankle of mechanically ventilated adults. Twenty accelerometers were available to guarantee uninterrupted actigraphy recording 24 hours/day. Data were analyzed: (1) between awakening and ICU discharge to quantify daytime PA/SB and (2) between admission and ICU discharge to quantify day/nighttime inactivity. Secondarily, we assessed the relationship between inactivity/SB and clinical variables. Results: Thirty patients were enrolled, obtaining 5477 recording hours. No patient reported discomfort or injury. The median (min-max) delay time between admission and accelerometer installation was 2.1 (0.0-11.9) hours. Actigraphy recording duration was 5.4 (2.2-34.4) days. The time spent in SB and PA (percentage of minutes per hour) was 94.7% and 5.3%, respectively. PA was stratified by light, moderate, and vigorous levels equating to 91.8%, 7.7%, and 0.5%, respectively. Inactivity time (r = 0.991, P ≤ .001) and SB (r = 0.859, P ≤ .001) were strongly correlated with ICU length of stay. Conclusions: Quantifying PA levels with continuous monitoring through actigraphy is feasible, demonstrating prolonged periods of inactivity/SB. This study highlights that uninterrupted actigraphy could contribute to pursuing the optimal dose and the intervention fidelity of the ICU mobilization in the subsequent clinical trials.

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Daily compliance of the ABCDEF liberation bundle for patients in the intensive care unit: A retrospective descriptive study

2024 , Felipe Muñoz-Muñoz , LEPPE ZAMORA, JAIME ESTEBAN , Felipe González-Seguel , CASTRO AVILA, ANA CRISTINA

Introduction Implementing the ABCDEF bundle has demonstrated improved outcomes in patients with critical illness. This study aims to describe the daily compliance of the ABCDEF bundle in a Chilean intensive care unit. Methods Retrospective observational study of electronic clinical records of nursing, physiotherapy, and medical professionals who cared for patients over 18 years of age, admitted to an intensive care unit for at least 24 hours, with or without mechanical ventilation. Daily bundle compliance was determined by considering the daily records for each element: Assess pain (element A), both spontaneous awakening trials (element B1) and spontaneous breathing trials (element B2), choice of sedation (element C), delirium assessment (element D), early mobilization (element E), and family engagement (element F). Results 4165 registered bundle elements were obtained from nursing (47%), physiotherapy (44%), and physicians (7%), including 1134 patient/days (from 133 patients). Elements E and C showed 67 and 40% compliance, while D, A, and B2 showed 24, 14 and 11%, respectively. For B1 and F, 0% compliance was achieved. Compliance was higher in patients without mechanical ventilation for A and E, while it was similar for D. Conclusions Early mobilization had the highest compliance, while spontaneous awakening trials and family engagement had absolute non-compliance. Future studies should explore the reasons for the different degrees of compliance per bundle element in clinical practice.

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Reporte de notas de actividad física en Chile: Contribuyendo en una iniciativa global por niños y adolescentes más activos

2016 , Nicolás Aguilar-Farías , Andrea Cortínez , Jaime Leppe-Zamora , Teresa Balboa , Carolina Cobos , Nicolás Lemus , Macarena Valladares , Kabir Sadarangani , Astrid Von Oetinger , Magdalena Walbaum , Carlos Cristi-Montero

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Inter-observer reliability of trained physiotherapists on the Functional Status Score for the Intensive Care Unit Chilean-Spanish version

2020 , GONZALEZ SEGUEL, FELIPE ANDRES , CAMUS MOLINA, AGUSTIN , Marcela Cárcamo , Stephanie Hiser , Dale M. Needham , LEPPE ZAMORA, JAIME ESTEBAN

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The boundaries of mild chronic obstructive pulmonary disease (COPD): Design of the searching clinical COPD onset (SOON) study

2017 , Gonzalo Labarca , Andrea Bustamante , Gonzalo Valdivia , Rodrigo Díaz , Álvaro Huete , Paul Mac Nab , Laura Mendoza , Jaime Leppe , Carmen Lisboa , Fernando Saldías , Orlando Díaz

IntroductionClinical onset of chronic obstructive pulmonary disease (COPD) is the point at which the disease is first identifiable by physicians. It is a poorly defined stage which seems to include both mild spirometric and non-spirometric disease, and could be described as early grade COPD, for practical purposes. While dyspnoea; chronic bronchitis and CT imaging evidence of emphysema and airway disease may be present very early, the lone significance of dyspnoea, the most relevant symptom in COPD in identifying these individuals, has been scarcely assessed.The Searching Clinical COPD Onset (SOON) Study was designed primarily to detect clinical, physiological and structural differences between dyspnoeic and non-dyspnoeic individuals with early grade COPD. It is hypothesised that presence of dyspnoea in early disease may identify a subtype of individuals with reduced exercise capacity, notwithstanding of their spirometry results. In addition, dyspnoeic individuals will share worse quality of life, lower physical activity, greater lung hyperinflation greater emphysema and airway thickness and reduced peripheral muscle mass than their non-dyspnoeic counterpart.Methods and analysisSOON is a monocentric study, with a cross sectional design aimed at obtaining representative samples of current or ex-smoker-adults aged ≥45 and ≤80 years. Two hundred and forty participants will be enrolled into four strata, according to normal spirometry or mild spirometric obstruction and presence or not of dyspnoea modified Medical Research Council score ≥1. The primary outcome will be the difference between dyspnoeic and non-dyspnoeic individuals on the 6-min walk test performance, regardless of their spirometry results. To account for the confounding effect of heart failure on dyspnoea, stress echocardiography will be also performed. Secondary outcomes will include clinical (quality of life, physical activity), physiological (exercise testing) and structural characteristics (emphysema, airway disease and peripheral muscle mass by CT imaging).Ethics and disseminationThe Institutional Ethics Committee from Pontificia Universidad Católica de Chile has approved the study protocol and signed informed consent will be obtained from all participants. The findings of the trial will be disseminated through relevant peer-reviewed journals and international conference presentations.Trial registration numberNCT03026439.

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The descriptive epidemiology of sitting in Chilean adults: Results from the National Health Survey 2009-2010

2019 , Nicolas Aguilar-Farias , Pia Martino-Fuentealba , Andrea Cortinez-O'Ryan , Damian Chandia-Poblete , Carlos A. Celis-Morales , Paz Bahamondes , LEPPE ZAMORA, JAIME ESTEBAN , Wendy J. Brown

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Recent Versus Old Previous Injury and Its Association with Running-Related Injuries During Competition by SeRUN® Running Profiles: a Cross-sectional Study

2018 , LEPPE ZAMORA, JAIME ESTEBAN , BESOMI MOLINA, MANUELA

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Self-perception of upper limbs swelling and four diagnostic criteria for lymphedema in women treated for breast cancer

2017 , LEPPE ZAMORA, JAIME ESTEBAN

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SeRUN (R) study: Development of running profiles using a mixed methods analysis

2018 , BESOMI MOLINA, MANUELA , Jaime Leppe , Maria Cristina Di Silvestre , Jenny Setchell , Yih-Kuen Jan

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Construct Validity of the Chilean-Spanish Version of the Functional Status Score for the Intensive Care Unit: A Prospective Observational Study Using Actigraphy in Mechanically Ventilated Patients

2020 , CAMUS MOLINA, AGUSTIN , Felipe González-Seguel , CASTRO AVILA, ANA CRISTINA , LEPPE ZAMORA, JAIME ESTEBAN

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