ALMEIDA TORO, JUAN MANUEL
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ALMEIDA TORO, JUAN MANUEL
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jalmeida@udd.cl

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Topic: AS15 COVID and Stroke IMPACTOF COVID-19 PANDEMIC ON STROKE SEVERITYAND MORTALITY IN THE SOUTH-EAST OF SANTIAGO, CHILE

2021 , ALMEIDA TORO, JUAN MANUEL , NAVIA GONZALEZ, VICTOR HUGO , GARCÍA PRADO, DIEGO RICARDO , Silva, A. , Vallejos, J. , Uribe, R. , Martoni, M. , Miranda, M. , Diaz, P.

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Stroke care and collaborative academic research in Latin America

2022 , MUÑOZ VENTURELLI, PAULA ANDREA , RECULE GONZALEZ, FRANCISCA , Francisca Urrutia , MAZZON AGURTO, ENRICO , NAVIA GONZALEZ, VICTOR HUGO , BRUNSER, ALEJANDRO , LAVADOS GERMAIN, PABLO MANUEL , OLAVARRIA IANISZEWSKY, VERONICA VIVIANA , ALMEIDA TORO, JUAN MANUEL , Rodrigo Guerrero , Alexis Rojo , Juan Pablo Gigoux , José Vallejos , Nathalie Conejan , Tomas Esparza , Arturo Escobar , Alvaro Soto , Octavio Pontes-Neto , Antonio Arauz , Carlos Abanto , Cheryl Carcel , Jessica Hanae Zafra-Tanaka , Hueiming Liu , Lili Song , J Jaime Miranda , Craig S Anderson

Objective. A narrative overview of regional academic research collaborations to address the increasing burden and gaps in care for patients at risk of, and who suffer from, stroke in Latin America (LA). Materials and methods. A summary of experiences and knowledge of the local situation is presented. No systematic literature review was performed. Results. The rapidly increasing burden of stroke poses immense challenges in LA, where prevention and manage­ment strategies are highly uneven and inadequate. Clinical research is increasing through various academic consortia and networks formed to overcome structural, funding and skill barriers. However, strengthening the ability to generate, analyze and interpret randomized evidence is central to further develop effective therapies and healthcare systems in LA. Conclusions. Regional networks foster the conduct of multicenter studies –particularly randomized controlled trials–, even in resource-poor regions. They also contribute to the external validity of international studies and strengthen systems of care, clinical skills, critical thinking, and international knowledge exchange.

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Impact of Evidence‐Based Stroke Care on Patient Outcomes: A Multilevel Analysis of an International Study

2019 , MUÑOZ VENTURELLI, PAULA ANDREA , Xian Li , Sandy Middleton , Caroline Watkins , LAVADOS GERMAIN, PABLO MANUEL , OLAVARRIA IANISZEWSKY, VERONICA VIVIANA , BRUNSER, ALEJANDRO , Octavio Pontes‐Neto , Taiza E. G. Santos , Hisatomi Arima , Laurent Billot , Maree L. Hackett , Lily Song , Thompson Robinson , Craig S. Anderson , Gillian Mead , H. Asita De Silva , Jeyaraj D. Pandian , Ruey‐Tay Lin , Tsong‐Hai Lee , Liying Cui , Bin Peng , Stephane Heritier , Richard Lindley , Stephen Jan , Elizabeth Boaden , Christopher P. L. H. Chen , Anne Forster , Laurent Billot , Mark Woodward , Kris Rogers , Anish Scaria , Joyce Y. Lim , Natalie Espinosa , Lucy McEvoy , Lee Blackburn , Sarah S. Richtering , Shoujiang You , Simon Ladwig , Gabrielle P. Merritt , Bryce Thomsen , Kerry Jenson , Penelope Gordon , Dennis Ryan Nguyen , Wei Wei Quan , Tessa Pei‐Yi Lo , Jonathan Lim , Selena Goh , Leibo Liu , Mirza Ahmad Baig , Ravider Singh , Paul Donnelly , Manuela Armenis , Marna Van Zyl , Helen Monaghan , Phillipa Smith , Parisa Glass , Fanli Zhou , Yun Shen , Li Lei , Di Li , Ting Zhang , Xiaoyan Zhang , Yun Peng , Lingling Feng , Zhiping Ye , Philip Gregory , Jeyaraj D. Pandain , Deepti Arora , Pablo M. Lavados , GONZALEZ, FRANCISCA , Bernardita Portales , Octavio Pontes‐Neto , Taiza Santos‐Pontelli , Brunna Rimoli , Monica Braga , Carolina Vidal , Dafna Benadof , Rodrigo J. Rivas , Laura Carvallo , Pamela Carvallo , Rubia Miranda , Brunna Pileggi , H. Asita de Silva , Shalomi Weerawardena , Thanushanthan Jeevarajah , Devaki Dharmawardena , Dumindi Ranasinghe , Matheesha Dharshana , Nilesh Nandadeva , Savithri Nawarathna , Ruey‐Tay Lin , Tsong‐Hai Lee , Jiu‐Haw Yin , Shoou‐Jeng Yeh , Ruei‐Jen Ma , Caroline L. Watkins , Gemma Whiteley , Denise Forshaw , Catherine Elizabeth Lightbody , Joanna Cox , Jane Fitzgerald , John F. Heney , Helen Byfield , Simone Finley , Hayley E. Tyrer , Carole Bruce , Alison Gibbon , Brett Jones , Emma Siracusa , Koushik Gowda , Shahla Cowans , Briana Forman , Sherin Jacob , Kristine Caprecho , Roshan Khatri , Po Yi Wan , Maria Lopez , Sifiso Vanika , Wilhelmina Bleeker , Marinka Ireland , Sheila Jala , Susan Day , Eric Ha , Martin Krause , Melissa Passer , Sarah Giaccari , Nadia Burkolter , Michael Braithwaite , Kylie Tastula , Darshan Ghia , Tapuwa Musuka , Anthony Alvaro , Gillian Edmonds , Nicole O'Loughin , Rebecca Phair , Joanne Kaoutal , David J. Blacker , Belinda L Saint , Kim Parrey , Michelle Coad , Matthew Kinchington , Nishantha Senanayake , Johanna Alaban , Irma Kuehne , Taiza Santos‐Pontelli , Monica Braga , Brunna Rimoli , Millene Camilo , Milena Libardi , Sheila Martins , Batista Carlos , Magda Martins , Leonardo Carbonera , Andrea Almeida , Martin Kelin , Carla Pauli , Mariana Lunardi , Luciane Silveira , Olga Chagas , Daily Souza , Gabriel Braga , Priscila Ribeiro , Gustavo Luvizutto , Marcia Polin , Fernanda Winckler , Jinfeng Liu , Zhenjiang Wang , Huibing Wang , Suying Lin , Jing Dong , Junshan Zhou , Suping Qin , Hui Zhan , Yongquan Xue , Dong Tian , Dan Yang , Yan Yin , He Li , Changming Geng , Jieyi Liu , Xiaolin Jiang , Yujun Wu , Wei Sun , Bingqi Yu , Yanmei Guan , Qin Wang , Bo Wei , Huirong Wang , Yan Wang , Liwen Tai , Wenchao Zhang , Weili Zhao , Xueying Wang , Guoli Li , Zhiming Ni , Fudong Guo , Lan Cen , Jun Lu , Zheng Chen , Guoming Yin , Yingchun Wang , Jiping Zheng , Zhimin Zhou , Hongquan Wang , Renlin Zou , Bin Xue , Airu Li , Jing Guo , Ying Guo , Xingguo Jiang , Xiuge Tan , Chunpeng Zhang , Bei Shao , Xiaoting Niu , Chunfeng Liu , Dongqin Chen , Ping Liang , Xia Zhang , Chunqing Zhang , Wenjie Gong , Zhichao Huang , Huihui Liu , Shoujiang You , Junying Huang , Rongfang Shi , Cuilan Wang , Ying Liu , Jinchao Wang , Guojun Wu , Zhihong Gao , Qunli Lin , Cong Xu , Huile Zheng , Xinghai Ye , Xiaoqiong Jin , Junyan Liu , Xiaoyun Cao , Yan Zhang , Jinyang Wang , Yuzhu Xu , Yan Li , Xin Ma , Qi Kong , Yanlei Hao , Baojun Qiao , Hui Yan , Zhiyong Huang , Baoqiang Chang , Jinjin Yan , Pinjun Liao , Wei Zhang , Ling Liu , Tingting Zhu , Xuehui Liu , Yongping Li , Ruifang Dong , Miao Chen , Xiaoli Ge , Hairong Wang , Lihua Dai , Jiafu Liu , Shixia Wang , Jihui Du , Aixiu Song , Yunhai Li , Jie Feng , Cheng Yu , Honglin Feng , Xiaojia Sun , Ruihong Sun , Weisong Liu , Jianfeng Liu , Xuesheng Lu , Enzhuo Chen , Wei Gao , Hui Liu , Heping Wang , Yanxia Wang , Juan Song , Dongqi Liu , Wenhui Du , Guixia Li , Cuiling Li , Yanling Liang , Xuekun Cai , Jinli Zhang , Xiaowei Tao , Pingshun An , Ranran Tang , Xu Qin , Yingling Wang , Wenjun Zhang , Rong Ma , Xiaoqiong Huang , Yonglin Liu , Yazhi Wang , Ping Fan , Hailan Yang , Lianyuan Feng , Jianxia Zhi , Jiewen Zhang , Yao Zhou , Danhong Wu , Haiyan He , Xiaohong Chen , Yongge Hou , Xiaohui Su , Liying Cui , Bin Peng , Siyuan Fan , Luis Suárez , Juan de Dios Polanco , Patricio Sotomayor , Ricardo Urzúa , Daniela Urrutia , Nathalie Conejan , Arturo Escobar , Monica Gonzalez , Danisa Vargas , Angel Constante , Erika Vásquez , Elizabeth Godoy , Christian Figueroa , Vanesa San Martin , Nataly Vidal , Madeleyn Muñoz , María Spencer , BRUNSER, ALEJANDRO , ALMEIDA TORO, JUAN MANUEL , Ignacio Acosta , Rodrigo Guerrero , Prudencio Lozano , Camila Aguayo , Jimena Pizarro , Alvaro Soto , Flor Bonilla , Pía García , Carolina Del Castillo , Marcela Grandjean , Alexis Von Johnn , Ignacio Gutierrez , Francisca Rivero , Ignacio López , Federico Silva , Marlen Pachón , José Mendoza , Alexander Pabón , Mahesh Kate , Naushad Akhtar , Gibbsdeep S. Narang , Ashish Deepak , Vikram Huded , Romnesh De Sowza , Alben Sigamani , Karthikeyan Rajendran , Anisha Vishwanath , Anusha K , Somasundaram Kumaravelu , Syed Rahamath , Sandeep Kannneganti , Dheeraj Khurana , Cheena Katoch , Taranpreet Kaur , Ummer Karadan , Anu Kuriakose , Jaison John , Mumthaz Basheer , Harsha Hemal Gunasekara , Gamlath Chandima Udeni De Silva , Peetagam Harshi Lakmali Ubeywickrama , Kavisha Chathumali Silva , Eshani Anuradha De Silva , Udaya Ranawaka , Chamila Mettananda , Yamuna Nanayakkara , Tharini Mendis , Gayathri Fernando , Ahamed Imthikab , Kandula Pieris , Saman B. Gunatilake , Pamuditha M. W. Madanayake , Shiran A. Paranavitane , Bimsara Senanayake , Vaidhehi Vishwanathan , Maathury Sivapalan , Ruwangi U. Murage , Uthpala Chandradeva , Ruey‐Tay Lin , Yao‐Hua Liu , Chih‐Lung Lin , Hsiu‐Fen Lin , Kuan‐Ting Liu , Chien‐Fu Chen , Meng‐Ni Wu , Su‐Hua Tsai , Chi‐Ching Chen , Lan‐Yi Chen , Tsong‐Hai Lee , Chien‐Hung Chang , Yeu‐Jhy Chang , Kuo‐Lun Huang , Ting‐Yu Chang , Chi‐Hung Liu , Chen‐June Seak , Yu‐Li Lin , Jia‐Yi Luo , Hsiao‐Ying Yang , Ching‐Yi Wang , Lung Chan , Chaur‐Jong Hu , Nai‐Fang Chi , Dean Wu , Yao‐Hsien Huang , Yi‐Chun Kuan , Chien‐Tai Hong , Yi‐Chun Chen , Yu Sun , Cheng‐Huai Lin , Chien‐Jung Lu , Hai‐Jui Chu , Yi‐Chia Lo , Wen‐Hui Chang , Wan‐Jung Lin , Hui‐Chen Su , Tien‐Yu Lin , Chi‐Hsuan Cho , Shu‐Lan Lu , Ya‐Fang Hsueh , Ching‐Yi Lai , David Jarrett , Claire James , Stacey Valentine , Clare Whistler , Rebecca Butler , Simone Browning , Caroline Watchurst , Renuka Erande , Emma Elliott , Krishna Patel , Maria Brezitski , Caroline Hogan , Asra Banaras , Lucinda Crook , Rashidat Ahmed , Lindsay Potter , Rosie Laird , Natasha Clarke , Alison Loosemore , J. Godber , Sara Gawned , K. A. Hamilton , Rachael Jones , Paul Guyler , Sharon Tysoe , Raji Prabakaran , Sweni Shah , Joanne Calver , Laszlo K. Sztriha , Maria Fitzpatrick , Stephanie Drysdale , John Aeron‐Thomas , Emma McKenzie , Belinda Chitando , Paul Willcoxson , Elizabeth Iveson , Peter Wanklyn , Natasha Dyer , Michael Keeling , Romina Rodriguez , Kerry Elliott , Mia Porteous , Mark O'Neill , Sheridan Orme , Carla Richardson , Janet Tomlinson , Suzanne Hawkins , Delia Bester , Carol Jeffs , Joanne Howard , Pauline Brown , Deborah Ward , Jennifer Turfrey , Leanne Raybould , Allison Bates , Sue O'Connell , Margaret O'Connor , Samantha Williams , Hedley C. A. Emsley , Alison McLoughlin , Sonia Raj , Bindu Gregary , Donna Doyle , G. M. Courtauld , C. Schofield , L. Lucas , A. Lydon , A. James , Kari Saastamoinen , Laura Howaniec , Premchand Daboo , Ali N. Ali , Emma Richards , Joanne Howe , Christine Kamara , Kathy Stocks , Ralf Lindert , Diana J. Day , Sarah Finlay , Joanne McGee , Jennifer Mitchell , Elaine Amis , Rosemary Macey , Suzanne Tauro , Lauren Henry , Sarah Cuddy , Andrew Steele , Kerry Mullen , Sarah Kirker , Murudappa Bhattad , Michael Carpenter , Prabal Datta , Ann Needle , Linda Jackson , Julie Ball , Rosie Beckitt , Nicola Chivers , Angela Bowring , Sara Eddy , Kevin Thorpe , Samantha Keenan , Alison Griffin , Stuart Maguire , Chris Patterson , Hawraman Ramadan , Ruth Bellfield , Michaela Hooley , Kelvin Stewart , Lucy Williams , Cara Gurney , Deborah Oliver , Maria Gardiner , Sarah Grayland , Mohit Bhandari , David M. Collas , Tolu Adesina , Saul Sundayi , Ruth Harvey , Emma Pope , Audrey Lam , Elaine Walker , Colin Merrill , Soma Banerjee , Kirsten Hannah Harvey , Sheila Mashate , Peter Wilding , Linda Johnson , Robert Namushi , Patricia Jacob , Sreeman Andole , Karen Dunne , Naveen Gadapa , Sam King , Sonata Siliuzaite , Sharon Dealing , Karen Attwood , Annette Woods , Banher Sandhu , Maam Mamun , Afzal Mahmood , June Jones , Abimbola Ojo , Denise Carter‐Evans , Royal Liverpool , Aravind Manoj , Glyn Fletcher , Paula Lopez , Jill Greig , Matthew Robinson , Sarah Jones , Lorinda Jones , Claire West , Helen Tench , Rachel Gascoyne , Amanda Whileman , Emily Hall , Stephanie Wright , Julie Toms , Janet Tomlinson , Duke Phiri , Sakthivel Sethuraman , Niaz Mohammed , Frances Justin , Margaret Louise Tate , Meena Chauhan , Syed I. Haider , Arumugam Nallasivan , Tim Webster , Sandra Leason , Samantha Seagrave , Peterborough City Hospital , Peter Owksu‐Agyei , Natalie Temple , Nicola Butterworth‐Cowin , Frederick Magezi , Leicester Royal Infirmary , Shagufta Khan , Claire Stephens , Amit Mistri , Aidan Murphy , Manda Lam , Paul Underwood , Catherine Thompson , Clare Buckley , Diane Wood , Sarah Board , Linda Howard , Ashraf Ahmed , Bethany Oates , Sara Leonard , Royal Bournemouth Hospital , Royal Bournemouth , Kamy Thavanesan , Michelle Dharmasiri , Sathyabama Logianathan , Catherine Ovington , Gail Hann , Chantel Cox , Craigavon Area Hospital , Southern Health , Social Care Trust , Catherine Douglas , Michael Goggin , Patricia Fearon , Sara Gilpin , Margaret O'Hagan , Pilgrim Hospital , Anne Hardwick , Kimberley Netherton , Judith Quinn , Tulu Bozkaplan , Josin Jose

Background The uptake of proven stroke treatments varies widely. We aimed to determine the association of evidence‐based processes of care for acute ischemic stroke ( AIS ) and clinical outcome of patients who participated in the HEADPOST (Head Positioning in Acute Stroke Trial), a multicenter cluster crossover trial of lying flat versus sitting up, head positioning in acute stroke. Methods and Results Use of 8 AIS processes of care were considered: reperfusion therapy in eligible patients; acute stroke unit care; antihypertensive, antiplatelet, statin, and anticoagulation for atrial fibrillation; dysphagia assessment; and physiotherapist review. Hierarchical, mixed, logistic regression models were performed to determine associations with good outcome (modified Rankin Scale scores 0–2) at 90 days, adjusted for patient and hospital variables. Among 9485 patients with AIS, implementation of all processes of care in eligible patients, or “defect‐free” care, was associated with improved outcome (odds ratio, 1.40; 95% CI, 1.18–1.65) and better survival (odds ratio, 2.23; 95% CI , 1.62–3.09). Defect‐free stroke care was also significantly associated with excellent outcome (modified Rankin Scale score 0–1) (odds ratio, 1.22; 95% CI , 1.04–1.43). No hospital characteristic was independently predictive of outcome. Only 1445 (15%) of eligible patients with AIS received all processes of care, with significant regional variations in overall and individual rates. Conclusions Use of evidence‐based care is associated with improved clinical outcome in AIS . Strategies are required to address regional variation in the use of proven AIS treatments. Clinical Trial Registration URL : https://www.clinicaltrials.gov . Unique Identifier: NCT 02162017.

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Yield of Echocardiography in the Evaluation of Cerebral Ischemic Events: A Single Center Cohort Study

2019 , BRUNSER, ALEJANDRO , Rodrigo Ibañez-Arenas , Martin Larico , Eloy Mansilla , ALMEIDA TORO, JUAN MANUEL , OLAVARRIA IANISZEWSKY, VERONICA VIVIANA , Alexis Rojo , MUÑOZ VENTURELLI, PAULA ANDREA , Gabriel Cavada , LAVADOS GERMAIN, PABLO MANUEL

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Global Impact of COVID-19 on Stroke Care and IV Thrombolysis

2021 , Raul G. Nogueira , Muhammad M. Qureshi , Mohamad Abdalkader , Sheila Ouriques Martins , Hiroshi Yamagami , Zhongming Qiu , Ossama Yassin Mansour , Anvitha Sathya , Anna Czlonkowska , Georgios Tsivgoulis , Diana Aguiar de Sousa , Jelle Demeestere , Robert Mikulik , Peter Vanacker , James E. Siegler , Janika Kõrv , Jose Biller , Conrad W. Liang , Navdeep S. Sangha , Alicia M. Zha , Alexandra L. Czap , Christine Anne Holmstedt , Tanya N. Turan , George Ntaios , Konark Malhotra , Ashis Tayal , Aaron Loochtan , Annamarei Ranta , Eva A. Mistry , Anne W. Alexandrov , David Y. Huang , Shadi Yaghi , Eytan Raz , Sunil A. Sheth , Mahmoud H. Mohammaden , Michael Frankel , Eric Guemekane Bila Lamou , Hany M. Aref , Ahmed Elbassiouny , Farouk Hassan , Tarek Menecie , Wessam Mustafa , Hossam M. Shokri , Tamer Roushdy , Fred S. Sarfo , Tolulope Oyetunde Alabi , Babawale Arabambi , Ernest O. Nwazor , Taofiki Ajao Sunmonu , Kolawole Wahab , Joseph Yaria , Haytham Hussein Mohammed , Philip B. Adebayo , Anis D. Riahi , Samia Ben Sassi , Lenon Gwaunza , Gift Wilson Ngwende , David Sahakyan , Aminur Rahman , Zhibing Ai , Fanghui Bai , Zhenhui Duan , Yonggang Hao , Wenguo Huang , Guangwen Li , Wei Li , Ganzhe Liu , Jun Luo , Xianjin Shang , Yi Sui , Ling Tian , Hongbin Wen , Bo Wu , Yuying Yan , Zhengzhou Yuan , Hao Zhang , Jun Zhang , Wenlong Zhao , Wenjie Zi , Thomas W. Leung , Chandril Chugh , Vikram Huded , Bindu Menon , Jeyaraj Durai Pandian , PN Sylaja , Fritz Sumantri Usman , Mehdi Farhoudi , Elyar Sadeghi Hokmabadi , Anat Horev , Anna Reznik , Rotem Sivan Hoffmann , Nobuyuki Ohara , Nobuyuki Sakai , Daisuke Watanabe , Ryoo Yamamoto , Ryosuke Doijiri , Naoki Tokuda , Takehiro Yamada , Tadashi Terasaki , Yukako Yazawa , Takeshi Uwatoko , Tomohisa Dembo , Hisao Shimizu , Yuri Sugiura , Fumio Miyashita , Hiroki Fukuda , Kosuke Miyake , Junsuke Shimbo , Yusuke Sugimura , Yoshiki Yagita , Yohei Takenobu , Yuji Matsumaru , Satoshi Yamada , Ryuhei Kono , Takuya Kanamaru , Hidekazu Yamazaki , Manabu Sakaguchi , Kenichi Todo , Nobuaki Yamamoto , Kazutaka Sonoda , Tomoko Yoshida , Hiroyuki Hashimoto , Ichiro Nakahara , Aida Kondybayeva , Kamila Faizullina , Saltanat Kamenova , Murat Zhanuzakov , Jang-Hyun Baek , Yangha Hwang , Jin Soo Lee , Si Baek Lee , Jusun Moon , Hyungjong Park , Jung Hwa Seo , Kwon-Duk Seo , Sung Il Sohn , Chang Jun Young , Rechdi Ahdab , Wan Asyraf Wan Zaidi , Zariah Abdul Aziz , Hamidon bin Basri , Law Wan Chung , Aznita Binti Ibrahim , Khairul Azmi Ibrahim , Irene Looi , Wee Yong Tan , Nafisah Wan Yahya , Stanislav Groppa , Pavel Leahu , Amal M. Al Hashmi , Yahia Zakaria Imam , Naveed Akhtar , Maria Carissa Pineda-Franks , Christian Oliver Co , Dmitriy Kandyba , Adel Alhazzani , Hosam Al-Jehani , Carol Huilian Tham , Marlie Jane Mamauag , Narayanaswamy Venketasubramanian , Chih-Hao Chen , Sung-Chun Tang , Anchalee Churojana , Esref Akil , özlem aykaç , Atilla Ozcan Ozdemir , Semih Giray , Syed Irteza Hussain , Seby John , Huynh Le Vu , Anh Duc Tran , Huy Hoang Nguyen , Thong Nhu Pham , Thang Huy Nguyen , Trung Quoc Nguyen , Thomas Gattringer , Christian Enzinger , Monika Killer-Oberpfalzer , Flavio Bellante , Sofie De Blauwe , Geert Vanhooren , Sylvie De Raedt , Anne Dusart , Robin Lemmens , Noemie Ligot , Matthieu Pierre Rutgers , Laetitia Yperzeele , Filip Alexiev , Teodora Sakelarova , Marina Roje Bedeković , Hrvoje Budincevic , Igor Cindric , Zlatko Hucika , David Ozretic , Majda Seferovic Saric , František Pfeifer , Igor Karpowic , David Cernik , Martin Sramek , Miroslav Skoda , Helena Hlavacova , Lukas Klecka , Martin Koutny , Daniel Vaclavik , Ondrej Skoda , Jan Fiksa , Katerina Hanelova , Miroslava Nevsimalova , Robert Rezek , Petr Prochazka , Gabriela Krejstova , Jiri Neumann , Marta Vachova , Henryk Brzezanski , David Hlinovsky , Dusan Tenora , Rene Jura , Lubomír Jurák , Jan Novak , Ales Novak , Zdenek Topinka , Petr Fibrich , Helena Sobolova , Ondrej Volny , Hanne Krarup Christensen , Nicolas Drenck , Helle Klingenberg Iversen , Claus Z. Simonsen , Thomas Clement Truelsen , Troels Wienecke , Riina Vibo , Katrin Gross-Paju , Toomas Toomsoo , Katrin Antsov , Francois Caparros , Charlotte Cordonnier , Maria Dan , Jean-Marc Faucheux , Laura Mechtouff , Omer Eker , Emilie Lesaine , Basile Ondze , Roxane Peres , Fernando Pico , Michel Piotin , Raoul Pop , Francois Rouanet , Tatuli Gubeladze , Mirza Khinikadze , Nino Lobjanidze , Alexander Tsiskaridze , Simon Nagel , Peter Arthur Ringleb , Michael Rosenkranz , Holger Schmidt , Annahita Sedghi , Timo Siepmann , Kristina Szabo , Götz Thomalla , Lina Palaiodimou , Dimitrios Sagris , Odysseas Kargiotis , Peter Klivenyi , Laszlo Szapary , Gabor Tarkanyi , Alessandro Adami , Fabio Bandini , Paolo Calabresi , Giovanni Frisullo , Leonardo Renieri , Davide Sangalli , Anne Pirson , Maarten Uyttenboogaart , Ido van den Wijngaard , Espen Saxhaug Kristoffersen , Waldemar Brola , Małgorzata Fudala , Ewa Horoch-Lyszczarek , Michal Karlinski , Radoslaw Kazmierski , Pawel Kram , Marcin Rogoziewicz , Rafal Kaczorowski , Piotr Luchowski , Halina Sienkiewicz-Jarosz , Piotr Sobolewski , Waldemar Fryze , Anna Wisniewska , Malgorzata Wiszniewska , Patricia Ferreira , Paulo Ferreira , Luisa Fonseca , João Pedro Marto , Teresa Pinho e Melo , Ana Paiva Nunes , Miguel Rodrigues , Vítor Tedim Cruz , Cristian Falup-Pecurariu , Georgi Krastev , Miroslav Mako , María Alonso de Leciñana , Juan F. Arenillas , Oscar Ayo-Martin , Antonio Cruz Culebras , Exuperio Diez Tejedor , Joan Montaner , Soledad Pérez-Sánchez , Miguel Angel Tola Arribas , Alejandro Rodriguez Vasquez , Michael Mayza , Gianmarco Bernava , Alex Brehm , Paolo Machi , Urs Fischer , Jan Gralla , Patrik L. Michel , Marios-Nikos Psychogios , Davide Strambo , Soma Banerjee , Kailash Krishnan , Joseph Kwan , Asif Butt , Luciana Catanese , Andrew M. Demchuk , Thalia Field , Jennifer Haynes , Michael D. Hill , Houman Khosravani , Ariane Mackey , Aleksandra Pikula , Gustavo Saposnik , Courtney Anne Scott , Ashkan Shoamanesh , Ashfaq Shuaib , Samuel Yip , Miguel A. Barboza , Jose Domingo Barrientos , Ligia Ibeth Portillo Rivera , Fernando Gongora-Rivera , Nelson Novarro-Escudero , Anmylene Blanco , Michael Abraham , Diana Alsbrook , Dorothea Altschul , Anthony J. Alvarado-Ortiz , Ivo Bach , Aamir Badruddin , Nobl Barazangi , Charmaine Brereton , Alicia Castonguay , Seemant Chaturvedi , Saqib A. Chaudry , Hana Choe , Jae H. Choi , Sushrut Dharmadhikari , Kinjal Desai , Thomas G. Devlin , Vinodh T. Doss , Randall Edgell , Mark Etherton , Mudassir Farooqui , Don Frei , Dheeraj Gandhi , Mikayel Grigoryan , Rishi Gupta , Ameer E. Hassan , Johanna Helenius , Artem Kaliaev , Ritesh Kaushal , Priyank Khandelwal , Ayaz M. Khawaja , Naim N. Khoury , Benny S. Kim , Dawn O. Kleindorfer , Feliks Koyfman , Vivien H. Lee , Lester Y. Leung , Guillermo Linares , Italo Linfante , Helmi L. Lutsep , Lisa Macdougall , Shailesh Male , Amer M. Malik , Hesham Masoud , Molly McDermott , Brijesh P. Mehta , Jiangyong Min , Manoj Mittal , Jane G. Morris , Sumeet S. Multani , Fadi Nahab , Krishna Nalleballe , Claude B. Nguyen , Roberta Novakovic-White , Santiago Ortega-Gutierrez , Rahul H. Rahangdale , Pankajavalli Ramakrishnan , Jose Rafael Romero , Natalia Rost , Aaron Rothstein , Sean Ruland , Ruchir Shah , Malveeka Sharma , Brian Silver , Marc Simmons , Abhishek Singh , Amy K. Starosciak , Sheryl L. Strasser , Viktor Szeder , Mohamed Teleb , Jenny P. Tsai , Barbara Voetsch , Oscar Balaguera , Virginia A. Pujol Lereis , Adriana Luraschi , Marcele Schettini Almeida , Fabricio Buchdid Cardoso , Adriana Conforto , Leonardo De Deus Silva , Luidia Varrone Giacomini , Fabricio Oliveira Lima , Alexandre L. Longo , Pedro S.C. Magalhães , Rodrigo Targa Martins , Francisco Mont'alverne , Daissy Liliana Mora Cuervo , Leticia Costa Rebello , Lenise Valler , Viviane Flumignan Zetola , LAVADOS GERMAIN, PABLO MANUEL , Victor Navia , OLAVARRIA IANISZEWSKY, VERONICA VIVIANA , Juan Manuel Almeida Toro , Pablo Felipe Ricardo Amaya , Hernan Bayona , Angel Corredor , Carlos Eduardo Rivera Ordonez , Diana Katherine Mantilla Barbosa , Osvaldo Lara , Mauricio R. Patiño , Luis Fernando Diaz Escobar , Donoband Edson Dejesus Melgarejo Fariña , Analia Cardozo Villamayor , Adolfo Javier Zelaya Zarza , Danny Moises Barrientos Iman , Liliana Rodriguez Kadota , Bruce Campbell , Graeme J. Hankey , Casey Hair , Timothy Kleinig , Alice Ma , Rodrigo Tomazini Martins , Ramesh Sahathevan , Vincent Thijs , Daniel Salazar , Teddy Yuan-Hao Wu , Diogo C. Haussen , David Liebeskind , Dileep R. Yavagal , Tudor G. Jovin , Osama O. Zaidat , Thanh N. Nguyen

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Diffusion-weighted imaging determinants for acute ischemic stroke diagnosis in the emergency room

2018 , BRUNSER, ALEJANDRO , Gabriel Cavada , MUÑOZ VENTURELLI, PAULA ANDREA , OLAVARRIA IANISZEWSKY, VERONICA VIVIANA , Alexis Rojo , ALMEIDA TORO, JUAN MANUEL , DIAZ TAPIA, VIOLETA DEL CARMEN , HOPPE WIEGERING, ARNOLD JOHANNES GOTTLIEB , LAVADOS GERMAIN, PABLO MANUEL

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INCIDENCE OF STROKE IN A HIGH CARDIOVASCULAR RISK POPULATION IN CHILE: THE NUBLE REGION, CEREBROVASCULAR ATTACK INCIDENCE AND DEATH COMMUNITY SURVEILLANCE AND INTERVENTION STUDY (NANDU)

2018 , LAVADOS GERMAIN, PABLO MANUEL , MUÑOZ VENTURELLI, PAULA ANDREA , OLAVARRIA IANISZEWSKY, VERONICA VIVIANA , PORTALES, MARÍA BERNARDITA , ALMEIDA TORO, JUAN MANUEL , Hoffmeister, L. , Moraga, A. M. , Vejar, A. , Gajardo, C. , San Martin, D.

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Impact of COVID-19 Pandemic on Stroke Severity and Mortality in the South-East of Santiago, Chile

2021 , Andres Silva-Pozo , Jose Vallejos , ALMEIDA TORO, JUAN MANUEL , Mariano Martoni , Reinaldo Uribe-San Martin , María Miranda , Pablo Diaz , Dominga García , NAVIA GONZALEZ, VICTOR HUGO

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Low dosis of alteplase, for ischemic stroke after Enchanted and its determinants, a single center experience

2020 , BRUNSER, ALEJANDRO , MAZZON AGURTO, ENRICO , Gabriel Cavada , Eloy Mansilla , Alexis Rojo , ALMEIDA TORO, JUAN MANUEL , OLAVARRIA IANISZEWSKY, VERONICA VIVIANA , MUÑOZ VENTURELLI, PAULA ANDREA , LAVADOS GERMAIN, PABLO MANUEL

Abstract Background: Low-dose alteplase (LrtPA) has been shown not to be inferior to the standard-dose (SrtPA) with respect to death/disability. Objective: We aim to evaluate the percentage of patients treated with LrtPA at our center after the ENCHANTED trial and the factors associated with the use of this dosage. Methods: Prospective study in consecutive patients with an acute stroke admitted between June 2016 and November 2018. Results: 160 patients were treated with intravenous thrombolysis, 50% female; mean age 65.4±18.5 years. Of these, 48 patients (30%) received LrtPA. In univariate analysis, LrtPA was associated with patient's age (p=0.000), previous modified Rankin scale scores (mRS) (p<0.000), hypertension (p=0.076), diabetes mellitus (p=0.021), hypercholesterolemia (p=0.19), smoking (p=0.06), atrial fibrillation (p=0.10), history of coronary artery disease (p=0.06), previous treatment with antiplatelet agents (p<0.000), admission International Normalized Ratio-INR (p=0.18), platelet count (p=0.045), leukoaraiosis on neuroimaging (p<0.003), contraindications for thrombolytic treatment (p=0.000) and endovascular treatment (p=0.027). Previous relevant bleedings were determinants for treatment with LrtPA. Final diagnosis on discharge of stroke mimic was significant (p=0.02) for treatment with SrtPA. In multivariate analysis, mRS (OR: 2.21; 95%CI 1.37‒14.19), previous antiplatelet therapy (OR: 11.41; 95%CI 3.98‒32.70), contraindications for thrombolysis (OR: 56.10; 95%CI 8.81‒357.80), leukoaraiosis (OR: 4.41; 95%CI 1.37‒14.10) and diagnosis of SM (OR: 0.22; 95%CI 0.10‒0.40) remained independently associated. Conclusions: Following the ENCHANTED trial, LrtPA was restricted to 30% of our patients. The criteria that clinicians apply are based mostly on clinical variables that may increase the risk of brain or systemic hemorrhage or exclude the patient from treatment with lytic drugs.

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Publication

Stroke awareness and response in Chile: a transversal study using a telephone survey

2021 , Mazzon, E , Navia, V. , Hoffmeister, L. , OLAVARRIA IANISZEWSKY, VERONICA VIVIANA , ALMEIDA TORO, JUAN MANUEL , BRUNSER RABOVICH, ALEJANDRO MICHEL , MUÑOZ VENTURELLI, PAULA ANDREA , LAVADOS GERMAIN, PABLO MANUEL

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