REYES ARAMBURU, EDISON PABLO
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REYES ARAMBURU, EDISON PABLO
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preyes@udd.cl
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35870354700

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LPS-Induced c-Fos Activation in NTS Neurons and Plasmatic Cortisol Increases in Septic Rats Are Suppressed by Bilateral Carotid Chemodenervation

2012 , REYES ARAMBURU, EDISON PABLO , Sebastián Abarzúa , Aldo Martin , Jorge Rodríguez , Paula P. Cortés , Ricardo Fernández

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Lipopolysaccharide-Induced Ionized Hypocalcemia and Acute Kidney Injury in Carotid Chemo/Baro-Denervated Rats

2015 , R. Fernández , P. Cortés , R. Del Rio , C. Acuña-Castillo , REYES ARAMBURU, EDISON PABLO

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Tau Platelets Correlate with Regional Brain Atrophy in Patients with Alzheimer's Disease

2017 , SLACHEVSKY CHONCHOL, ANDREA MARÍA , Leonardo Guzmán-Martínez , Carolina Delgado , Pablo Reyes , Gonzalo A. Farías , Carlos Muñoz-Neira , Eduardo Bravo , Mauricio Farías , Patricia Flores , Cristian Garrido , James T. Becker , Oscar L. López , Ricardo B. Maccioni , Paulo Caramelli

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Cxs and Panx- hemichannels in peripheral and central chemosensing in mammals

2014 , Edison Pablo Reyes , Verónica Cerpa , Liliana Corvalán , Mauricio Antonio Retamal

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Comparison of achievement in anamnesis skills in on-site and online formative Objective Structured Clinical Exam

2023 , Mariana Jadue , Pilar Munitiz , Luz-María Torres , Marcelo Blacutt , Soledad Armijo-Rivera , REYES ARAMBURU, EDISON PABLO

Introduction: anamnesis is an initial step of the clinical reasoning process, which is taught throughout interviews to real or simulated patients. Its evaluation through OSCEs is widely disseminated, and in the context of a pandemic, the OSCE was adapted to be administered online. Objective: to compare the levels of achievement in anamnesis skills of two cohorts of medical students in formative OSCEs of semiology in on-site and online modality. Methods: using a blueprint established in 2017 and implemented for three years, competencies were identified that could be trained and evaluated online in third-year medical students. Telesimulations were performed with role play for anamnesis ability. Guided by a tutor, each student participated in 10 telesimulated anamnesis with peer roleplay and one anamnesis with a simulated pacientent. All of it in groups of 6 students. A formative TeleOSCE was implemented, evaluating the same skills of the year 2019 in a face-to-face training instance. In 2019 and 2020, 92 and 91 students participated respectively. The students' performance was compared in three identical scenarios. Results: at the cough, acute diarrhea, and knee pain screening scenarios, students in the 2020 cohort performed better than those in the 2019 cohort (p<0,001). Conclusions: for the development of anamnesis skill in third-year medical students, telesimulation-based teaching allows students to demonstrate adequate performance on a practical assessment administered online via TeleOSCE.

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Shifting from Hypoxia to Hyperoxia to Assess the Peripheral Chemosensory Drive of Ventilation

0002 , Patricio Zapata , Carolina Larraín , Edison-Pablo Reyes , Ricardo Fernández

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Sepsis progression to multiple organ dysfunction in carotid chemo/baro-denervated rats treated with lipopolysaccharide

2015 , Gino Nardocci , Aldo Martin , Sebastián Abarzúa , Jorge Rodríguez , Felipe Simon , REYES ARAMBURU, EDISON PABLO , Claudio Acuña-Castillo , Cristina Navarro , Paula P. Cortes , Ricardo Fernández

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Evaluating the reliability of neurocognitive biomarkers of neurodegenerative diseases across countries: A machine learning approach

2020 , M. Belen Bachli , Lucas Sedeño , Jeremi K. Ochab , Olivier Piguet , Fiona Kumfor , Pablo Reyes , Teresa Torralva , María Roca , Juan Felipe Cardona , Cecilia Gonzalez Campo , Eduar Herrera , Andrea Slachevsky , Diana Matallana , Facundo Manes , Adolfo M. García , Agustín Ibáñez , Dante R. Chialvo

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Multivariate word properties in fluency tasks reveal markers of Alzheimer's dementia

2023 , Franco J. Ferrante , Joaquín Migeot , Agustina Birba , Lucía Amoruso , Gonzalo Pérez , Eugenia Hesse , Enzo Tagliazucchi , Claudio Estienne , Cecilia Serrano , SLACHEVSKY CHONCHOL, ANDREA MARÍA , Diana Matallana , Pablo Reyes , Agustín Ibáñez , Sol Fittipaldi , Cecilia Gonzalez Campo , Adolfo M. García

AbstractINTRODUCTIONVerbal fluency tasks are common in Alzheimer's disease (AD) assessments. Yet, standard valid response counts fail to reveal disease‐specific semantic memory patterns. Here, we leveraged automated word‐property analysis to capture neurocognitive markers of AD vis‐à‐vis behavioral variant frontotemporal dementia (bvFTD).METHODSPatients and healthy controls completed two fluency tasks. We counted valid responses and computed each word's frequency, granularity, neighborhood, length, familiarity, and imageability. These features were used for group‐level discrimination, patient‐level identification, and correlations with executive and neural (magnetic resonanance imaging [MRI], functional MRI [fMRI], electroencephalography [EEG]) patterns.RESULTSValid responses revealed deficits in both disorders. Conversely, frequency, granularity, and neighborhood yielded robust group‐ and subject‐level discrimination only in AD, also predicting executive outcomes. Disease‐specific cortical thickness patterns were predicted by frequency in both disorders. Default‐mode and salience network hypoconnectivity, and EEG beta hypoconnectivity, were predicted by frequency and granularity only in AD.DISCUSSIONWord‐property analysis of fluency can boost AD characterization and diagnosis.Highlights We report novel word‐property analyses of verbal fluency in AD and bvFTD. Standard valid response counts captured deficits and brain patterns in both groups. Specific word properties (e.g., frequency, granularity) were altered only in AD. Such properties predicted cognitive and neural (MRI, fMRI, EEG) patterns in AD. Word‐property analysis of fluency can boost AD characterization and diagnosis.

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Design of an eOSCE for the Chilean Healthcare Context

2022 , ZAMORANO URRUTIA, FRANCISCO JAVIER , Mauricio Reyes , Germán Espinoza , REYES ARAMBURU, EDISON PABLO

Objective Structured Clinical Examination (OSCE) is the standard to assess and train clinical skills in healthcare students. However, conducting an OSCE demands expensive resources such as time, qualified personnel, and adequate facilities. The aim to provide more cost-effective examinations has promoted the emergence of electronic versions of OSCEs (eOSCEs). However, existing eOSCEs available in the market do not adequately adapt to diverse local contexts. For a Spanish-speaking country such as Chile, implementing foreign eOSCEs requires to adjust the examination to unfamiliar terminology, archetypes, and procedures, thus hindering the quality of the assessment. This article reports on the design of Ch-eOSCE, an eOSCE tailored for the Chilean local context and culture. Ch-eOSCE is comprised of a mobile application and a back-end system. A prototype of the application was developed and tested with three healthcare experts to gather their perception of usability and coherence, yielding an overall evaluation of 4.5 in a scale range of 5. The preliminary results reveal that Ch-eOSCE has the potential to become a viable solution for a context-specific eOSCE for the Chilean healthcare context.

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