CASTRO MENDEZ, ALEX
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CASTRO MENDEZ, ALEX
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alexcastro@udd.cl
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Scopus Author ID
57207343550

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Signo de rueda de carreta en los nódulos tiroídeos: ¿Sinónimo de benignidad?

2011 , HORVATH POLOS, ELEONORA , Felipe González I , SILVA FUENTE ALBA, CLAUDIO SERGIO , CASTRO MENDEZ, ALEX , Sergio Majlis D , Juan P Niedmann E , Daniel Gaete D , WHITTLE PINTO, CAROLINA

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Dermatoscopy of an Angiomatoid Spitz Nevus

2011 , CABRERA MORAGA, RAUL ALEJANDRO , Francisca Daza , Denis Tom , Victor G Prieto , CASTRO MENDEZ, ALEX

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Acrodermatitis enteropática: caso clínico y revisión de la literatura

2013 , CASTRO MENDEZ, ALEX , Michelle Mauret , Roberto Valdés

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Polypoid melanoma: An aggressive variant of nodular melanoma

2018 , Pérez-Wilson, Jaime , Arellano, Javier , CASTRO MENDEZ, ALEX

Genetic evidence for a trimeric structure for purine nucleoside phosphorylase in the brook lamprey is presented. This enzyme is encoded by a single locus with two alleles segregating at frequencies of 0.98 and 0.02 in a Welsh population. It is suggested that this enzyme is likely to be a trimer in all classes of vertebrates.

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Extranodal Follicular Dendritic Cell Sarcoma Presenting on the Skin

2024 , Rosario Agüero , RECULE GONZALEZ, FRANCISCA , Jaime Pérez , CASTRO MENDEZ, ALEX

Abstract: Follicular dendritic cell sarcoma is a rare intermediate-grade malignancy characterized by a proliferation of ovoid to spindle-shaped cells with morphologic and immunophenotypic features similar to normal follicular dendritic cells. It may develop in lymph nodes or extranodal sites. Its presentation in extranodal tissues is a diagnostic challenge. It requires a high index of suspicion because follicular dendritic cell markers are not included in the routine immunohistochemical panels used for differential diagnosis. In an extensive review of the English literature, we found 3 cases of follicular dendritic cell sarcoma developing on the skin. We report a case of a primary cutaneous follicular dendritic cell sarcoma in a 28-year-old man, which presented as a 6-mm skin-colored nodule on the right forearm. We describe the morphologic and immunohistochemical features and a review of the literature.

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Cromhidrosis ecrina por hiperbilirrubinemia secundaria a terapia antirretroviral

2017 , Jaime Pérez W. , CABRERA MORAGA, RAUL ALEJANDRO , CASTRO MENDEZ, ALEX , Fernando Pérez , Agustina Romanello , Máximo Venegas , Viviana García

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Bullous Henoch-Schonlein purpura. Case report

2018 , MARIA TRINIDAD HASBUN ZEGPI , Ximena Chaparro , Viera Kaplan , Felipe Cavagnaro , CASTRO MENDEZ, ALEX

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Papular‐purpuric exanthem in a COVID‐19 patient: clinical and dermoscopic description

2020 , JORGE FELIPE LARRONDO GALVEZ , CABRERA MORAGA, RAUL ALEJANDRO , M. Gosch , F. Larrondo , AYLWIN RAMIREZ, MABEL CRISTINA , CASTRO MENDEZ, ALEX

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Demodicosis facial con respuesta exitosa a ivermectina tópica

2020 , Jaime Pérez , Consuelo Giordano , Viviana García , CASTRO MENDEZ, ALEX

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An Ultrasonogram Reporting System for Thyroid Nodules Stratifying Cancer Risk for Clinical Management

2009 , HORVATH POLOS, ELEONORA , Sergio Majlis , Ricardo Rossi , Carmen Franco , Juan P. Niedmann , CASTRO MENDEZ, ALEX , Miguel Dominguez

Abstract Context: There is a high prevalence of thyroid nodules on ultrasonographic (US) examination. However, most of them are benign. US criteria may help to decide cost-effective management. Objective: Our objective was to develop a standardized US characterization and reporting data system of thyroid lesions for clinical management: the Thyroid Imaging Reporting and Data System (TIRADS). Design: This was a prospective study using the TIRADS, which is based on the concepts of the Breast Imaging Reporting Data System of the American College of Radiology. Materials: A correlation of the US findings and fine needle aspiration biopsy (FNAB) results in 1959 lesions biopsied under US guidance and studied histologically during an 8-yr period was divided into three stages. In the first stage, 10 US patterns were defined. In the second stage, four TIRADS groups were defined according to risk. The percentages of malignancy defined in the Breast Imaging Reporting and Data System were followed: TIRADS 2 (0% malignancy), TIRADS 3 (<5% malignancy), TIRADS 4 (5–80% malignancy), and TIRADS 5 (>80% malignancy). Results: The TIRADS classification was evaluated at the third stage of the study in a sample of 1097 nodules (benign: 703; follicular lesions: 238; and carcinoma: 156). Sensitivity, specificity, positive predictive value, negative predictive value, and accuracy were 88, 49, 49, 88, and 94%, respectively. The ratio of benign to malignant or follicular FNAB results currently is 1.8. Conclusions: The TIRADS has allowed us to improve patient management and cost-effectiveness, avoiding unnecessary FNAB. In addition, we have established standard codes to be used both for radiologists and endocrinologists.

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