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Bespoke science: the use of ad hoc scientific advisory committees in the Covid-19 pandemic
(Springer Science and Business Media LLC, 2025-06-19)
Roger Koppl
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Kira Pronin
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Nick Cowen
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Marta Podemska-Mikluch
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PANIAGUA PRIETO, PABLO IGNACIO
Many governments formed ad hoc scientific advisory committees in the Covid-19 pandemic because they offered the government greater control over policy advice than standing agencies. The difference between ad hoc and standing advisory bodies has been little noted in the literature. High-uncertainty crises demanding expertise and requiring action from the national government increase the value of policy discretion, raising the value of controlling the scientific narrative. An ad hoc body is generally easier to control than a standing body because policymakers have greater liberty to choose its members, specify its mandate, and disband and reconstitute it when needed. Control generally requires either a narrow membership or a narrow mandate. If members cannot be chosen to be reliably aligned with the government or its policy preferences, a narrow mandate will restrain the committee from offering undesired advice or analysis. Our argument builds on the public choice assumption of motivational symmetry: The choices of scientists and politicians are shaped by the same motives and desires that influence individuals in any other sphere of life. Our case studies of Italy, UK, US, Poland, Uganda, and Sweden support our theory.
Scopus© Citations 2 3
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Resilience of mobility network to dynamic population response across COVID-19 interventions: Evidences from Chile
(Public Library of Science (PLoS), 2025-02-20)
Pasquale Casaburi
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Lorenzo Dall’Amico
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Nicolò Gozzi
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Kyriaki Kalimeri
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Anna Sapienza
The COVID-19 pandemic highlighted the importance of non-traditional data sources, such as mobile phone data, to inform effective public health interventions and monitor adherence to such measures. Previous studies showed how socioeconomic characteristics shaped population response during restrictions and how repeated interventions eroded adherence over time. Less is known about how different population strata changed their response to repeated interventions and how this impacted the resulting mobility network. We study population response during the first and second infection waves of the COVID-19 pandemic in Chile and Spain. Via spatial lag and regression models, we investigate the adherence to mobility interventions at the municipality level in Chile, highlighting the significant role of wealth, labor structure, COVID-19 incidence, and network metrics characterizing business-as-usual municipality connectivity in shaping mobility changes during the two waves. We assess network structural similarities in the two periods by defining mobility hotspots and traveling probabilities in the two countries. As a proof of concept, we simulate and compare outcomes of an epidemic diffusion occurring in the two waves. While differences exist between factors associated with mobility reduction across waves in Chile, underscoring the dynamic nature of population response, our analysis reveals the resilience of the mobility network across the two waves. We test the robustness of our findings recovering similar results for Spain. Finally, epidemic modeling suggests that historical mobility data from past waves can be leveraged to inform future disease spatial invasion models in repeated interventions. This study highlights the value of historical mobile phone data for building pandemic preparedness and lessens the need for real-time data streams for risk assessment and outbreak response. Our work provides valuable insights into the complex interplay of factors driving mobility across repeated interventions, aiding in developing targeted mitigation strategies.
2
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Reducing global inequities in medical oxygen access: the Lancet Global Health Commission on medical oxygen security
(Elsevier BV, 2025-03)
Hamish R Graham
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Carina King
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Ahmed Ehsanur Rahman
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Freddy Eric Kitutu
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Leith Greenslade
Scopus© Citations 53 1
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Therapeutic trajectories of families with rare diseases in Chile from the perspectives of patients, carers, and healthcare workers: a qualitative study
(Springer Science and Business Media LLC, 2025-02-25)
CABIESES VALDES, BALTICA BEATRIZ
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OBACH KING, ALEXANDRA ALICE
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Antonia Roberts
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REPETTO LISBOA, MARIA GABRIELA
Background Rare diseases are conditions that have a low prevalence in the population and a high disease burden and are often chronic and progressive. International evidence concerning the experience of people and families living with rare diseases is scarce, leading to late and erroneous diagnoses, as well as non-specific treatments. This study explored the therapeutic trajectories of people and families living with rare diseases within Chile’s public and private healthcare systems from the perspective of patients, caregivers, and medical teams, including the initial symptoms, first consultation, testing, diagnosis, treatment, and follow-up. Methods A qualitative exploratory study was conducted through multiple case studies. Sixty participants were interviewed in person and/or virtually: patients (n = 16), caregivers (n = 22), healthcare workers (n = 20), and two patient organisation leaders. The material was analysed using thematic analysis. The project was approved by the Scientific Ethics Committee of Facultad de Medicina Clínica Alemana, Universidad del Desarrollo. Results After similar initial symptoms and first consultation, three main types of trajectories were identified: (i) the path taken by those who reach a diagnosis for a disease that has specific treatment available; (ii) the journey of those who reach a diagnosis for their health condition, but their disease does not have a specific treatment available; and (iii) the trajectory of those who have not reached a diagnosis and receive symptomatic treatments for symptoms. Conclusions The therapeutic trajectories of patients with rare symptoms are similar in terms of initial symptoms and first consultation. However, their paths diverge at the diagnostic stage, with diverse experiences related to these journeys, largely based on having a diagnosis and whether there is a specific treatment. Rare conditions in Chile requires further attention and urgent action that considers those who live with them and their families.
1
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Lack of treatment options for endemic helminth infections in Chile affects patient care and public health
(Elsevier BV, 2025-06)
WEITZEL, THOMAS
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María Elvira Balcells
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Claudia P. Cortes
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Alberto Fica
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Renzo Tassara
2
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Exploring the characteristics of cancer-centred civil society organisations in Chile: A qualitative study
(Public Library of Science (PLoS), 2025-05-16)
Antonia Roberts
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Francisca Vezzani
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CABIESES VALDES, BALTICA BEATRIZ
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OBACH KING, ALEXANDRA ALICE
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CAMPAÑA, CARLA
In Chile, civil society organisations in health have been historically active in population health and specifically in cancer; they have had an important role in addressing patients’ and families’ necessities. Although they occupy a central role, there is no clarity about who they are, how they are organised, the goals that guide their performance and how they materialize social participation in health. Based on that, this study aimed to explore the characteristics of civil society organisations that work in cancer in Chile and to identify the networks they build with other actors to achieve their goals. Materials and methods Qualitative case study using semi-structured online interviews with organisation representatives, politicians, decision-makers and academics related to cancer in Chile. Content analysis was performed, admitting emerging categories from the participants’ narratives.</jats:p> Results Three main profiles of organisations were identified: (i) Long-established organisations focused on influencing public policy and decision-making in cancer, (ii) Growing organisations focused on informing and supporting families and patients, (iii) Newly established organisations focused on patient well-being, such as sports activities. Relationships between groups and other actors involve perceived benefits like the growth of the organisations and funding for activities. However, perceived barriers and inequities are also identified, mainly lack of financial resources, competition between organisations and insufficient information. Discussion The objectives of civil society organisations in cancer are diverse and reflect multiple ways of practising social participation in health. Tensions generate unequal participation and missed opportunities to promote public health in cancer in Chile. The study highlights the importance of recognising cancer social organisations as essential actors in public health. It is crucial to involve them in formulating and implementing comprehensive responses to maximise the opportunities for progress in this field.
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Cáncer de vesícula: ¿Es momento de modificar el GES?
(SciELO Agencia Nacional de Investigacion y Desarrollo (ANID), 2024-10)
Camila P. Samaniego
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Xabier de Aretxabala
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Felipe Castillo
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Álvaro Paredes
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M. Trinidad González
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Cancer plans should consider local needs
(Elsevier BV, 2025-02)
Bettina Müller
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Raul Murillo
1Scopus© Citations 2
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“Hasta que me embaracé no conocí matrona”: salud sexual y reproductiva de jóvenes mujeres mapuche, Chile
(FapUNIFESP (SciELO), 2024)
CARREÑO CALDERON, ALEJANDRA ANGELICA
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OBACH KING, ALEXANDRA ALICE
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Correa-Matus, Eliana
<jats:p>Resumen Este estudio pretende explorar la prevención y promoción de salud sexual y reproductiva en jóvenes mapuche de entre 18 y 24 años, indagando en las relaciones que establecen con el sistema de salud biomédico y en los desafíos para la inclusión de la interculturalidad en las prestaciones dirigidas a esta población. Se trata de una investigación cualitativa de estudio de caso. Se aplicaron 32 entrevistas en profundidad a jóvenes mapuche de sectores rurales y urbanos de la región de la Araucanía, Chile. Se identifica la persistencia un abordaje sanitario que carece de herramientas interculturales y de enfoque de derechos sexuales y reproductivos. Las jóvenes reportan falta de acceso a educación sexual tanto por la distancia que establecen con los servicios biomédicos de atención primaria como por las dificultades de hablar de sexualidad con los adultos de sus comunidades. Se concluye que persisten inequidades en el derecho a la salud sexual y reproductiva de jóvenes indígenas, especialmente en mujeres. Es necesario incorporar el enfoque intercultural y de derechos en la formulación de políticas públicas para esta población. Tales intervenciones requieren ser diseñadas e implementadas involucrando tanto a la población joven como a los agentes de salud de sus comunidades de origen.</jats:p>
3
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The risk of high-biomass HABs: Triggers and dynamics of a non-toxic bloom of Prorocentrum micans in Chilean Patagonia
(Elsevier BV, 2025-01)
Patricio A. Díaz
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Leila Basti
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Iván Pérez-Santos
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Camila Schwerter
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Osvaldo Artal
7

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