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    Evidence-based clinical standard for the diagnosis and treatment of invasive lung aspergillosis in the patient with oncohematologic disease
    (Elsevier BV, 2025-03)
    Jorge Alberto Cortés
    ;
    Diego Andrés Rodríguez-Lugo
    ;
    Martha Carolina Valderrama-Rios
    ;
    Ricardo Rabagliati
    ;
    Domenico Capone
      2
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    Latin America Cutaneous Oncology Management (LACOM) I: The Role of Skin Care in Oncology Patients and Survivors
    (SanovaWorks, 2025-02-01)
    Daniel Alcalá Pérez
    ;
    Ana Sofia Acosta Madiedo
    ;
    Sebastian Andreani
    ;
    Anneke Andriessen
    ;
    Hebert Cárdenas
      2
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      5
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    Individualized evaluation of the total dose received by radiotherapy patients: Integrating in-field, out-of-field, and imaging doses
    (Elsevier BV, 2025-01)
    Maite Romero-Expósito
    ;
    Beatriz Sánchez-Nieto
    ;
    Mercedes Riveira-Martin
    ;
    Mona Azizi
    ;
    Angeliki Gkavonatsiou
    Scopus© Citations 10  9
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    Spanish version of the ICIQ-Bowel questionnaire among colorectal cancer patients: construct and criterion validity
    (2023)
    SACOMORI, CINARA  
    ;
    Luz Alejandra Lorca
    ;
    Mónica Martinez-Mardones
    ;
    Marta Natalia Pizarro-Hinojosa
    ;
    Gonzalo Sebastián Rebolledo-Diaz
    <jats:title>Abstract</jats:title><jats:sec> <jats:title>Purpose</jats:title> <jats:p>Bowel complaints are very common among patients with colorectal cancer. However, the most used questionnaires for colorectal cancer survivors do not comprehensively comprise bowel symptoms. This study aimed to examine construct and criterion validity, as well as internal consistency, of the Chilean Version of the International Consultation on Incontinence Questionnaire Bowel Module (ICIQ-B) among people with colorectal cancer.</jats:p> </jats:sec><jats:sec> <jats:title>Methods</jats:title> <jats:p>Cross-sectional, validation study performed with 106 colorectal cancer patients from Hospital del Salvador, Chile. Bowel function was assessed with the ICIQ-B. Construct validity was assessed with confirmatory factor analysis and hypothesis testing. Specific items of a quality-of-life questionnaire (EORTC QLQ-CR29) were used to correlate with similar ICIQ-B items for criterion validity. For internal consistency, Cronbach’s alpha was computed.</jats:p> </jats:sec><jats:sec> <jats:title>Results</jats:title> <jats:p>For construct validity, the confirmatory factor analysis showed that the three factors model did not fit our data. Meanwhile, hypothesis testing favored the construct validity of the instrument, considering that rectal cancer patients showed worse bowel pattern (p = 0.001), bowel control (p = 0.001) and quality of life (p &lt; 0.001) scores compared to colon cancer patients. In addition, those patients assessed before surgery also presented worse scores bowel control (p = 0.023) and quality of life (p = 0.009) compared to post-surgical patients. Regarding criterion validity, the ICIQ-B items showed a significant correlation with similar QLQ-CR29 items. The internal reliability of the instrument was good (Cronbach’s α = 0.909).</jats:p> </jats:sec><jats:sec> <jats:title>Conclusion</jats:title> <jats:p>Considering that this questionnaire appraises bowel function in more depth, it is recommended for use in clinical practice and research with colorectal cancer patients.</jats:p> </jats:sec>
      2Scopus© Citations 4
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    International Expert Consensus on US Lexicon for Thyroid Nodules
    (2023)
    Cosimo Durante
    ;
    Laszlo Hegedüs
    ;
    Dong Gyu Na
    ;
    Enrico Papini
    ;
    Jennifer A. Sipos
      6Scopus© Citations 61
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    ASO Author Reflections: Precision in Gallbladder Cancer Care: Present Challenges and Future Directions
    (2023)
    Sebastian Mellado
    ;
    Ariana M. Chirban
    ;
    Belen Rivera
    ;
    Elena Panettieri
    ;
    Eduardo A. Vega
      1Scopus© Citations 1
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    Development and internal validation of a multifactorial risk prediction model for gallbladder cancer in a high‐incidence country
    (2023)
    Felix Boekstegers
    ;
    Dominique Scherer
    ;
    Carol Barahona Ponce
    ;
    Katherine Marcelain
    ;
    Valentina Gárate‐Calderón
    <jats:title>Abstract</jats:title><jats:p>Since 2006, Chile has been implementing a gallbladder cancer (GBC) prevention program based on prophylactic cholecystectomy for gallstone patients aged 35 to 49 years. The effectiveness of this prevention program has not yet been comprehensively evaluated. We conducted a retrospective study of 473 Chilean GBC patients and 2137 population‐based controls to develop and internally validate three GBC risk prediction models. The Baseline Model accounted for gallstones while adjusting for sex and birth year. Enhanced Model I also included the non‐genetic risk factors: body mass index, educational level, Mapuche surnames, number of children and family history of GBC. Enhanced Model II further included Mapuche ancestry and the genotype for rs17209837. Multiple Cox regression was applied to assess the predictive performance, quantified by the area under the precision‐recall curve (AUC‐PRC) and the number of cholecystectomies needed (NCN) to prevent one case of GBC at age 70 years. The AUC‐PRC for the Baseline Model (0.44%, 95%CI 0.42‐0.46) increased by 0.22 (95%CI 0.15‐0.29) when non‐genetic factors were included, and by 0.25 (95%CI 0.20‐0.30) when incorporating non‐genetic and genetic factors. The overall NCN for Chileans with gallstones (115, 95%CI 104‐131) decreased to 92 (95%CI 60‐128) for Chileans with a higher risk than the median according to Enhanced Model I, and to 80 (95%CI 59‐110) according to Enhanced Model II. In conclusion, age, sex and gallstones are strong risk factors for GBC, but consideration of other non‐genetic factors and individual genotype data improves risk prediction and may optimize allocation of financial resources and surgical capacity.</jats:p>
      5Scopus© Citations 16
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      7Scopus© Citations 8
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    Recurrence of hepatocellular carcinoma after liver transplantation: Prognostic and predictive factors of survival in a Latin American cohort
    (2020)
    Claudia Maccali
    ;
    Aline L. Chagas
    ;
    Ilka Boin
    ;
    Emilio Quiñonez
    ;
    Sebastián Marciano
      13Scopus© Citations 18