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    Protocol for outpatient management in cleft lip and palate repair
    (2021)
    María Santos
    ;
    Jacqueline García
    ;
    Stephanie Graf
    ;
    Carlos Giugliano
      11Scopus© Citations 7
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    Return to sport soccer after anterior cruciate ligament reconstruction: ISAKOS consensus
    (2022) ;
    Guillermo Arce
    ;
    João Espregueira-Mendes
    ;
    Rodrigo Maestu
    ;
    Manuel Mosquera
      18Scopus© Citations 23
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    High-Grade Patellar Chondral Defects: Promising Results From Management With Osteochondral Autografts
    <jats:sec><jats:title>Background:</jats:title><jats:p>Patellar chondral defects represent up to 34.6% of defects found during routine arthroscopy. Surgical management has evolved during the past 20 years in an effort to develop techniques to replace hyaline cartilage. Currently, the only technique that achieves this is osteochondral autologous transfer (OAT). Although good and excellent results have often been reported at midterm and long-term follow-up for femoral lesions, little is known about isolated patellar defects.</jats:p></jats:sec><jats:sec><jats:title>Purpose:</jats:title><jats:p>To assess clinical and imaging results of patients treated with OAT for high-grade patellar defects.</jats:p></jats:sec><jats:sec><jats:title>Study Design:</jats:title><jats:p>Case series; Level of evidence, 4.</jats:p></jats:sec><jats:sec><jats:title>Methods:</jats:title><jats:p>This was a retrospective study on all patients who received OAT for high-grade symptomatic patellar chondral defects between 2010 and 2018 at our institution. The study included patients younger than 40 years of age with anterior knee pain and a grade 4 International Cartilage Repair Society patellar chondral defect between 1 and 2.5 cm<jats:sup>2</jats:sup>. Patients with surgery in other knee compartments, concomitant anterior cruciate ligament ruptures, infection, rheumatoid arthritis, and degenerative lesions were excluded. Six months postoperatively, all patients underwent magnetic resonance imaging (MRI) to allow assessment of graft integrity via the MOCART (Magnetic Resonance Observation of Cartilage Repair Tissue) score to evaluate morphologic features and integration. Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC) and Kujala scores were used to assess functional outcomes at final follow-up.</jats:p></jats:sec><jats:sec><jats:title>Results:</jats:title><jats:p>A total of 26 patients who received a patellar OAT were included. Most patients were male (88.4%), and the mean ± SD age was 28.5 ± 9.7 years. Patellar chondral defects had a median size of 180 mm<jats:sup>2</jats:sup>(range, 64-250 mm<jats:sup>2</jats:sup>), and patients received a median of 1 autograft (range, 1-3). Functional outcomes assessed at a minimum of 1 year after surgery showed a mean Kujala score of 90.42 ± 6.7 and a mean WOMAC score of 95 ± 3.6. MRI revealed a median MOCART score of 75 points (range, 20-90 points).</jats:p></jats:sec><jats:sec><jats:title>Conclusion:</jats:title><jats:p>To our knowledge, this is the largest series to date regarding isolated patellar OAT. At midterm follow-up, most patients reported good and excellent results regarding symptoms and activity levels. Most autografts showed good osseous integration and excellent filling of the chondral surface, as evidenced on MRI. OAT is a good alternative to treat high-grade patellar chondral defects, especially among young patients.</jats:p></jats:sec>
    Scopus© Citations 11  1
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    Pathological axis fracture secondary to a solitary bone plasmacytoma: Two cases and a literature review
    (2021) ;
    Alvaro Silva
    ;
    Matias Delgado
    ;
    Marilaura Nuñez
    ;
    Juan Lopez
    <jats:sec id="st1"> <jats:title>Background: </jats:title> <jats:p>Solitay bone plasmocytoma (SBP) account for just 5–10% of all plasma cell neoplasms. They are infrequent in the cervical spine, especially involving the C0–C2 segment. In this article we conducted a literature review and present the diagnosis, management and long term course of two patients with SBP of C2 causing cervical instability.</jats:p> </jats:sec> <jats:sec id="st2"> <jats:title>Methods: </jats:title> <jats:p>We assessed the clinical records of two patients with SBP in C2 and cervical instability attributed to SP-B involving C2. Both patients presented with progressive, severe cervicalgia, and the “sensation” of skull instability. Magnetic resonance imaging revealed an extensive, infiltrative lesion involving C2 vertebral body and lateral masses, consistent with a plasmacytoma.</jats:p> </jats:sec> <jats:sec id="st3"> <jats:title>Results: </jats:title> <jats:p>Both patients underwent emergency posterior surgical stabilization with craniocervical fixation; this was accompanied by a C2 transpedicular biopsy. Postoperatively, patients exhibited no focal neurological deficits and rapidly became pain free. They additional recieved 25 sessions of local conventional radiation therapy. Both patients are doing well as respective 2 and 7-year follow-up.</jats:p> </jats:sec> <jats:sec id="st4"> <jats:title>Conclusion: </jats:title> <jats:p>Although rare, unstable SBP may present atypical cervical location that readily responds to surgical descompression/fusion and radiotherapy.</jats:p> </jats:sec>
    Scopus© Citations 2  1
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    Spatiotemporal Differences in Gene Expression Between Motor and Sensory Autografts and Their Effect on Femoral Nerve Regeneration in the Rat
    (2019)
    David Hercher
    ;
    Markus Kerbl
    ;
    Christina M. A. P. Schuh
    ;
    Johannes Heinzel
    ;
    László Gal
      5Scopus© Citations 9
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    Presoaking of Hamstring Autografts in Vancomycin Decreases the Occurrence of Infection Following Primary Anterior Cruciate Ligament Reconstruction
    (2019)
    David Figueroa
    ;
    ; ;
    Mario Lopez
    ;
    Ignacio Goñi
    <jats:sec><jats:title>Background:</jats:title><jats:p> Postoperative septic arthritis is an uncommon but potentially devastating complication after anterior cruciate ligament (ACL) reconstruction. Our group started presoaking grafts with vancomycin to decrease this risk. </jats:p></jats:sec><jats:sec><jats:title>Purpose:</jats:title><jats:p> To compare the rate of septic arthritis in primary hamstring autograft ACL reconstruction with and without vancomycin-presoaked grafts. </jats:p></jats:sec><jats:sec><jats:title>Study Design:</jats:title><jats:p> Cohort study; Level of evidence, 3. </jats:p></jats:sec><jats:sec><jats:title>Methods:</jats:title><jats:p> Consecutive periods were studied, inclusive of April 2013 through October 2015 (pre-vancomycin protocol) and November 2015 through May 2018 (vancomycin protocol). A total of 490 patients were included in the study: 230 in the pre-vancomycin protocol and 260 in the vancomycin protocol. All patients who underwent a primary hamstring autograft ACL reconstruction by 2 senior surgeons during the periods studied were included. The final outcome studied was occurrence of highly probable postoperative septic arthritis in both groups. Diagnosis of probable septic arthritis was made by clinical diagnosis as well as cytological analysis of joint aspiration (cell count &gt;50,000/μL and &gt;90% neutrophils). Statistical analysis was performed with the Fisher exact test. Significance was set at P &lt; .05. </jats:p></jats:sec><jats:sec><jats:title>Results:</jats:title><jats:p> Four cases of probable postoperative septic arthritis were noted in the pre-vancomycin protocol (1.7%; 2 cases per surgeon), while no cases of septic arthritis were noted in the vancomycin protocol during the study period ( P &lt; .05). Diagnosis was made at a mean 21.7 days (range, 16-25 days). Staphylococcus epidermidis was isolated in 2 cases, and in the other 2 cases, no organism was isolated. </jats:p></jats:sec><jats:sec><jats:title>Conclusion:</jats:title><jats:p> Presoaking of hamstring autografts in vancomycin for primary ACL reconstruction prevented the occurrence of postoperative septic arthritis during the study period as compared with no soaking of the grafts. </jats:p></jats:sec>
      13Scopus© Citations 31
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    Biomechanical and geometric characterization of peroneus longus allografts with respect to age
    (2019)
    Andrew K. Wong
    ;
    ;
    Benjamin C. Schaffler
    ;
    Ryan A. Nixon
    ;
    Leanza C. Carrero
    Scopus© Citations 6  26