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    Risk factors and outcomes of pediatric non-invasive respiratory support failure in Latin America
    (2024)
    Diana Paola Escobar-Serna
    ;
    Juan Sebastian Barajas-Romero
    ;
    Juan Javier Peralta-Palmezano
    ;
    Juan Camilo Jaramillo-Bustamante
    ;
    Nicolas Monteverde-Fernandez
      2
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      12Scopus© Citations 13
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    Variability in care for children with severe acute asthma in Latin America
    (2020)
    Nicolas Monteverde‐Fernandez
    ;
    Franco Diaz‐Rubio
    ;
    Pablo Vásquez‐Hoyos
    ;
    Alexandre T. Rotta
    ;
    Sebastián González‐Dambrauskas
      12Scopus© Citations 5
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    Successful use of mild therapeutic hypothermia as compassionate treatment for severe refractory hypoxemia in COVID-19
    (2021)
    Pablo Cruces
    ;
    Camila Cores
    ;
    Daniel Casanova
    ;
    Federico Pizarro
    ;
    Franco Díaz
      2Scopus© Citations 13
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    No one is better than all together: the role of networks in pediatric intensive care
    (2019)
    Sebastián González-Dambrauskas
    ;
    Juan Camilo Jaramillo-Bustamante
    ;
    Franco Díaz
      1Scopus© Citations 5
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    Recomendaciones para el manejo inicial del síndrome inflamatorio multisistémico relacionado temporalmente con COVID-19, en niños y adolescentes
    (2020)
    Guillermo Kohn-Loncarica
    ;
    Ana Fustiñana
    ;
    Franco Díaz-Rubio
    ;
    Juan C. Jaramillo-Bustamante
    ;
    Sebastián González-Dambrauskas
    Scopus© Citations 12  1
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    Therapeutic variability in infants admitted to Latin-American pediatric intensive units due to acute bronchiolitis
    (2020)
    Jesús Alberto Serra
    ;
    Sebastián González-Dambrauskas
    ;
    Pablo Vásquez Hoyos
    ;
    CARVAJAL BENAVIDES, CÉSAR CRISTÓBAL  
    ;
    Alejandro Donoso
    <jats:p>Objetivo: describir las terapias utilizadas en lactantes con bronquiolitis aguda admitidos en 20 Unidades de Cuidados Intensivos (UCI) pediátricos miembros de LARed en 5 países latinoamericanos.Pacientes y Método: Estudio observacional retrospectivo, multicéntrico, de datos del Registro Latinoamericano de Falla Respiratoria Aguda Pediátrica. Se incluyeron niños menores de 2 años ingresados a UCI pediátrica por bronquiolitis aguda comunitaria entre mayo-septiembre 2017. Se recolectaron datos demográficos, clínicos, soporte respiratorio, terapias utilizadas y resultados clínicos. Se realizó análisis de subgrupos según ubicación geográfica, tipo financiación y presencia de academia.Resultados: Ingresaron al registro 1.155 pacientes con falla respiratoria aguda. Seis casos fueron excluidos por no tener formulario completo. De los 1.147 pacientes, 908 eran menores de 2 años. De ellos, 467 tuvieron diagnóstico de bronquiolitis aguda, correspondiendo a la principal causa de ingreso a UCI pediátrica por falla respiratoria aguda (51,4%). Las características demográficas y de gravedad entre los centros fueron similares. El soporte máximo respiratorio más frecuente fue cánula nasal de alto flujo (47%), seguido por ventilación mecánica no invasiva (26%) y ventilación mecánica invasiva (17%), con un coeficiente de variación (CV) amplio entre los centros. Hubo una gran dispersión en uso de terapias, siendo frecuente el uso de broncodilatadores, antibióticos y corticoides, con CV hasta 400%. El análisis de subgrupos mostró diferencias significativas en soporte respiratorio y tratamientos utilizados. Un paciente falleció en esta cohorte.Conclusión: Detectamos gran variabilidad en el soporte respiratorio y tratamientos entre UCI pediátricas latinoamericanas. Esta variabilidad no es explicada por disparidades demográficas ni clínicas. Esta heterogeneidad de tratamientos debería promover iniciativas colaborativas para disminuir la brecha entre la evidencia científica y la práctica asistencial.</jats:p>
      3Scopus© Citations 11
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    Successful extracorporeal membrane oxygenation therapy in a child with coronavirus 2019 disease-associated ARDS and chemotherapy for Ewing’s sarcoma
    (2022)
    Carmen Niño-Taravilla
    ;
    Yuri Zuleta-Morales
    ;
    Hugo Otaola-Arca  
    ;
    Benigno Montenegro
    ;
    Cristian Sotomayor F
    <jats:p> Most children and adolescents with SARS-CoV-2 infection show no or mild symptoms, but those with medical histories can be susceptible to more severe forms of disease. There are few reported cases of extracorporeal membrane oxygenation (ECMO) in pediatric patients with coronavirus disease 2019 (COVID-19). We present a previously healthy 13-year-old male diagnosed with metastatic Ewing’s sarcoma at the same time as catastrophic acute respiratory distress syndrome due to COVID-19, who was successfully supported by venovenous-ECMO while he received the corresponding chemotherapy protocol. </jats:p><jats:p> ECMO can be used as salvage therapy in oncology pediatric patients with respiratory failure secondary to COVID-19. In addition, successful chemotherapy can be administered while patients are supported on ECMO. </jats:p>
      3
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    Pediatric Inflammatory Multisystem Syndrome Associated With SARS-CoV-2
    (2020)
    Raúl Bustos B
    ;
    Juan Camilo Jaramillo-Bustamante
    ;
    Pablo Vasquez-Hoyos
    ;
    Pablo Cruces
    ;
    Franco Díaz
      13Scopus© Citations 24
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    Reduced PICU respiratory admissions during COVID-19
    (2020)
    Pablo Vásquez-Hoyos
    ;
    Franco Diaz-Rubio
    ;
    Nicolas Monteverde-Fernandez
    ;
    Juan Camilo Jaramillo-Bustamante
    ;
    CARVAJAL BENAVIDES, CÉSAR CRISTÓBAL  
    <jats:sec><jats:title>Background</jats:title><jats:p>The COVID-19 pandemic reached the Southern Hemisphere in the autumn of 2020, thus coinciding with its expected annual viral respiratory season. The potential impact of national strategies aimed at mitigating COVID-19 during the pandemic on the incidence of other critical viral lower respiratory tract infections (LRTIs) in children is unknown.</jats:p></jats:sec><jats:sec><jats:title>Methods</jats:title><jats:p>We analysed admission data for LRTIs from 22 paediatric intensive care units (PICUs) in four countries, part of a large international Latin American registry of children with acute respiratory failure (Red Colaborativa Pediátrica de Latinoamérica [LARed Network]).</jats:p></jats:sec><jats:sec><jats:title>Results</jats:title><jats:p>Between January and August, there were 83% fewer PICU admissions for LRTIs in 2020 compared to the 2018/2019 average over the same period. Similar decreases were noted for PICU admissions due to respiratory syncytial virus and influenza (92% and 78%, respectively).</jats:p></jats:sec><jats:sec><jats:title>Conclusion</jats:title><jats:p>We observed a striking reduction in PICU admissions due to viral LRTIs over winter, during the COVID-19 pandemic in South America.</jats:p></jats:sec>
    Scopus© Citations 59  1