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Author: search.filters.author.Sebastián González-Dambrauskas

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    Respiratory mechanics in infants with severe bronchiolitis on controlled mechanical ventilation
    (2017)
    Pablo Cruces
    ;
    Sebastián González-Dambrauskas
    ;
    Julio Quilodrán
    ;
    Jorge Valenzuela
    ;
    Javier Martínez
    Scopus© Citations 27  2
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    Characteristics of Medically Transported Critically Ill Children with Respiratory Failure in Latin America: Implications for Outcomes
    (2021)
    Jesus A. Serra
    ;
    Franco Díaz
    ;
    Pablo Cruces
    ;
    CARVAJAL BENAVIDES, CÉSAR CRISTÓBAL  
    ;
    Maria J. Nuñez
    <jats:title>Abstract</jats:title><jats:p>Several challenges exist for referral and transport of critically ill children in resource-limited regions such as Latin America; however, little is known about factors associated with clinical outcomes. Thus, we aimed to describe the characteristics of critically ill children in Latin America transferred to pediatric intensive care units for acute respiratory failure to identify risk factors for mortality. We analyzed data from 2,692 patients admitted to 28 centers in the Pediatric Collaborative Network of Latin America Acute Respiratory Failure Registry. Among patients referred from another facility (773, 28%), nonurban transports were independently associated with mortality (adjusted odds ratio = 9.4; 95% confidence interval: 2.4–36.3).</jats:p>
      4
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    Driving Pressure and Normalized Energy Transmission Calculations in Mechanically Ventilated Children Without Lung Disease and Pediatric Acute Respiratory Distress Syndrome*
    (2021)
    Franco Díaz
    ;
    Sebastián González-Dambrauskas
    ;
    Federico Cristiani
    ;
    Daniel R. Casanova
    ;
    Pablo Cruces
    Scopus© Citations 21  15
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    No one is better than all together: the role of networks in pediatric intensive care
    (2019)
    Sebastián González-Dambrauskas
    ;
    Juan Camilo Jaramillo-Bustamante
    ;
    Franco Díaz
      1Scopus© Citations 5
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    Therapeutic variability in infants admitted to Latin-American pediatric intensive units due to acute bronchiolitis
    (2020)
    Jesús Alberto Serra
    ;
    Sebastián González-Dambrauskas
    ;
    Pablo Vásquez Hoyos
    ;
    CARVAJAL BENAVIDES, CÉSAR CRISTÓBAL  
    ;
    Alejandro Donoso
    <jats:p>Objetivo: describir las terapias utilizadas en lactantes con bronquiolitis aguda admitidos en 20 Unidades de Cuidados Intensivos (UCI) pediátricos miembros de LARed en 5 países latinoamericanos.Pacientes y Método: Estudio observacional retrospectivo, multicéntrico, de datos del Registro Latinoamericano de Falla Respiratoria Aguda Pediátrica. Se incluyeron niños menores de 2 años ingresados a UCI pediátrica por bronquiolitis aguda comunitaria entre mayo-septiembre 2017. Se recolectaron datos demográficos, clínicos, soporte respiratorio, terapias utilizadas y resultados clínicos. Se realizó análisis de subgrupos según ubicación geográfica, tipo financiación y presencia de academia.Resultados: Ingresaron al registro 1.155 pacientes con falla respiratoria aguda. Seis casos fueron excluidos por no tener formulario completo. De los 1.147 pacientes, 908 eran menores de 2 años. De ellos, 467 tuvieron diagnóstico de bronquiolitis aguda, correspondiendo a la principal causa de ingreso a UCI pediátrica por falla respiratoria aguda (51,4%). Las características demográficas y de gravedad entre los centros fueron similares. El soporte máximo respiratorio más frecuente fue cánula nasal de alto flujo (47%), seguido por ventilación mecánica no invasiva (26%) y ventilación mecánica invasiva (17%), con un coeficiente de variación (CV) amplio entre los centros. Hubo una gran dispersión en uso de terapias, siendo frecuente el uso de broncodilatadores, antibióticos y corticoides, con CV hasta 400%. El análisis de subgrupos mostró diferencias significativas en soporte respiratorio y tratamientos utilizados. Un paciente falleció en esta cohorte.Conclusión: Detectamos gran variabilidad en el soporte respiratorio y tratamientos entre UCI pediátricas latinoamericanas. Esta variabilidad no es explicada por disparidades demográficas ni clínicas. Esta heterogeneidad de tratamientos debería promover iniciativas colaborativas para disminuir la brecha entre la evidencia científica y la práctica asistencial.</jats:p>
      3Scopus© Citations 11
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    Reduced PICU respiratory admissions during COVID-19
    (2020)
    Pablo Vásquez-Hoyos
    ;
    Franco Diaz-Rubio
    ;
    Nicolas Monteverde-Fernandez
    ;
    Juan Camilo Jaramillo-Bustamante
    ;
    CARVAJAL BENAVIDES, CÉSAR CRISTÓBAL  
    <jats:sec><jats:title>Background</jats:title><jats:p>The COVID-19 pandemic reached the Southern Hemisphere in the autumn of 2020, thus coinciding with its expected annual viral respiratory season. The potential impact of national strategies aimed at mitigating COVID-19 during the pandemic on the incidence of other critical viral lower respiratory tract infections (LRTIs) in children is unknown.</jats:p></jats:sec><jats:sec><jats:title>Methods</jats:title><jats:p>We analysed admission data for LRTIs from 22 paediatric intensive care units (PICUs) in four countries, part of a large international Latin American registry of children with acute respiratory failure (Red Colaborativa Pediátrica de Latinoamérica [LARed Network]).</jats:p></jats:sec><jats:sec><jats:title>Results</jats:title><jats:p>Between January and August, there were 83% fewer PICU admissions for LRTIs in 2020 compared to the 2018/2019 average over the same period. Similar decreases were noted for PICU admissions due to respiratory syncytial virus and influenza (92% and 78%, respectively).</jats:p></jats:sec><jats:sec><jats:title>Conclusion</jats:title><jats:p>We observed a striking reduction in PICU admissions due to viral LRTIs over winter, during the COVID-19 pandemic in South America.</jats:p></jats:sec>
    Scopus© Citations 59  1
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    Pediatric Critical Care and COVID-19
    (2020)
    Sebastián González-Dambrauskas
    ;
    Pablo Vásquez-Hoyos
    ;
    Anna Camporesi
    ;
    Franco Díaz-Rubio
    ;
    Byron Enrique Piñeres-Olave
    Scopus© Citations 80  1
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    Positive end-expiratory pressure improves elastic working pressure in anesthetized children
    (2018)
    Pablo Cruces
    ;
    Sebastián González-Dambrauskas
    ;
    Federico Cristiani
    ;
    Javier Martínez
    ;
    Ronnie Henderson
    Scopus© Citations 6  1